Gene Information

Name : CFSAN001921_02665 (CFSAN001921_02665)
Accession : YP_008253941.1
Strain : Salmonella enterica CFSAN001921
Genome accession: NC_021814
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein SipA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 542439 - 544496 bp
Length : 2058 bp
Strand : +
Note : cell invasion protein A; actin-binding; required for entry of the Salmonella into the host cell; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGGTTACAAGTGTAAGGACTCAGCCCCCCGTCATAATGCCAGGTATGCAGACCGAGATCAAAACGCAGGCCACGAATCT
TGCGGCGAATCTTTCCGCAGTCAGAGAAAGTGCCACAGCGACGCTGTCAGGGGAAATTAAAGGCCCGCAACTGGAAGATT
TTCCCGCGCTGATCAAACAGGCGAGTCTGGATGCATTGTTTAAATGCGGGAAAGACGCTGAGGCGTTAAAAGAAGTTTTT
ACCAATTCAAATAATGTCGCCGGTAAGAAAGCGATAATGGAGTTTGCCGGGCTCTTTCGTTCAGCGCTCAACGCCACCAG
TGATTCTCCTGAGGCGAAGACGCTACTGATGAAGGTGGGGGCAGAGTATACCGCGCAAATCATAAAAGATGGCCTGAAAG
AAAAGTCAGCTTTTGGGCCATGGCTGCCAGAAACAAAGAAAGCGGAAGCGAAGCTGGAAAACCTGGAAAAGCAGCTGTTA
GATATTATCAAAAATAACACTGGCGGTGAATTAAGTAAATTATCGACGAATCTTGTTATGCAGGAGGTGATGCCCTATAT
TGCCAGCTGCATTGAACATAACTTTGGCTGTACGTTAGATCCGTTAACCCGCAGCAATCTTACGCACCTTGTTGACAAAG
CGGCGGCGAAGGCTGTTGAGGCGCTTGATATGTGCCACCAAAAATTAACGCAAGAGCAGGGTACCAGCGTAGGACGGGAA
GCCCGGCACCTTGAAATGCAAACGTTGATACCCCTGCTGCTACGTAATGTTTTTGCACAAATTCCTGCAGATAAACTGCC
TGACCCTAAAATTCCGGAGCCTGCGGCTGGACCAGTACCTGATGGTGGGAAAAAAGCAGAACCTACGGGTATTAATATCA
ATATTAATATTGATAGCAGTAACCATAGCGTGGATAACAGTAAGCATATTAACAATAGCCGAAGCCATGTCGATAATAGC
CAGCGCCATATCGATAATAGCAACCATGATAATAGCCGGAAGACGATTGATAATAGCCGAACATTTATTGATAACAGCCA
ACGCAATGGCGAGTCACACCATTCGACTAACAGCAGCAACGTAAGTCATAGTCATTCGCGTGTGGATTCGACTACGCATC
AAACGGAGACGGCACACAGCGCCAGCACAGGGGCAATTGACCATGGCATCGCGGGTAAAATTGACGTCACGGCTCATGCG
ACGGCAGAGGCTGTGACCAACGCTTCATCCGAAAGTAAAGATGGAAAGGTGGTCACGTCAGAAAAGGGCACTACGGGTGA
AACAACCTCTTTTGATGAAGTCGATGGCGTAACCAGCAAGAGCATTATCGGCAAGCCGGTACAGGCCACGGTGCACGGCG
TTGATGATAATAAACAGCAAAGCCAGACGGCAGAGATTGTGAATGTGAAGCCGCTTGCCAGTCAACTGGCTGGCGTCGAG
AATGTTAAAACCGATACCTTACAATCAGACACGACGGTAATTACAGGTAATAAAGCCGGTACGACCGATAATGATAATAG
TCAGACAGATAAGACTGGCCCATTTTCTGGTTTGAAGTTTAAGCAAAATAGTTTCCTCTCAACAGTACCGAGCGTTACGA
ATATGCATTCAATGCATTTCGACGCCCGTGAGACGTTTTTGGGTGTGATACGTAAAGCCCTGGAGCCAGATACCTCCACA
CCGTTCCCTGTACGCAGAGCGTTTGACGGCTTGCGTGCGGAAATATTACCCAATGACACGATAAAGAGTGCAGCGTTGAA
AGCGCAATGTAGCGATATTGACAAGCACCCAGAATTGAAAGCGAAAATGGAGACTCTCAAAGAGGTCATTACTCATCATC
CACAAAAAGAAAAACTGGCTGAGATTGCACTGCAGTTTGCCAGAGAGGCGGGGCTGACCAGGCTAAAAGGGGAAACTGAC
TATGTGTTAAGTAATGTGCTGGACGGCCTTATCGGAGACGGTAGCTGGCGAGCTGGCCCGGCTTACGAGTCATACCTGAA
TAAACCTGGCGTGGATCGGGTTATTACTACCGTTGATGGCTTGCACATGCAGCGTTAA

Protein sequence :
MVTSVRTQPPVIMPGMQTEIKTQATNLAANLSAVRESATATLSGEIKGPQLEDFPALIKQASLDALFKCGKDAEALKEVF
TNSNNVAGKKAIMEFAGLFRSALNATSDSPEAKTLLMKVGAEYTAQIIKDGLKEKSAFGPWLPETKKAEAKLENLEKQLL
DIIKNNTGGELSKLSTNLVMQEVMPYIASCIEHNFGCTLDPLTRSNLTHLVDKAAAKAVEALDMCHQKLTQEQGTSVGRE
ARHLEMQTLIPLLLRNVFAQIPADKLPDPKIPEPAAGPVPDGGKKAEPTGINININIDSSNHSVDNSKHINNSRSHVDNS
QRHIDNSNHDNSRKTIDNSRTFIDNSQRNGESHHSTNSSNVSHSHSRVDSTTHQTETAHSASTGAIDHGIAGKIDVTAHA
TAEAVTNASSESKDGKVVTSEKGTTGETTSFDEVDGVTSKSIIGKPVQATVHGVDDNKQQSQTAEIVNVKPLASQLAGVE
NVKTDTLQSDTTVITGNKAGTTDNDNSQTDKTGPFSGLKFKQNSFLSTVPSVTNMHSMHFDARETFLGVIRKALEPDTST
PFPVRRAFDGLRAEILPNDTIKSAALKAQCSDIDKHPELKAKMETLKEVITHHPQKEKLAEIALQFAREAGLTRLKGETD
YVLSNVLDGLIGDGSWRAGPAYESYLNKPGVDRVITTVDGLHMQR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipA NP_461803.1 secreted effector protein Virulence SPI-1 Protein 0.0 100
sipA YP_217801.1 cell invasion protein Virulence SPI-1 Protein 0.0 99
sipA NP_457276.1 pathogenicity island 1 effector protein (function unknown) Virulence SPI-1 Protein 0.0 98
sipA NP_806485.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN001921_02665 YP_008253941.1 pathogenicity island 1 effector protein SipA VFG0543 Protein 0.0 100