Gene Information

Name : CFSAN001921_02640 (CFSAN001921_02640)
Accession : YP_008253936.1
Strain : Salmonella enterica CFSAN001921
Genome accession: NC_021814
Putative virulence/resistance : Virulence
Product : type III secretion system protein SpaS
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 536572 - 537642 bp
Length : 1071 bp
Strand : +
Note : Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGTCCTCGAATAAAACAGAAAAACCGACTAAAAAACGGCTGGAAGACTCCGCTAAAAAAGGCCAGTCATTTAAAAGTAA
AGATCTCATTATCGCCTGCCTGACGCTGGGAGGAATTGCCTATCTGGTGTCGTATGGCTCATTTAATGAGTTTATGGGGA
TAATTAAGATCATTATTGCGGATAATTTTGATCAGAGCATGGCTGACTACAGTTTGGCCGTTTTTGGGATAGGGTTAAAA
TATCTGATTCCATTTATGCTGCTCTGCTTAGTGTGTTCCGCATTACCGGCGTTATTACAGGCCGGTTTTGTGCTGGCGAC
AGAAGCATTAAAGCCTAATTTATCGGCGTTAAACCCGGTAGAAGGGGCAAAAAAACTTTTTAGTATGCGCACGGTTAAAG
ATACGGTCAAAACCCTACTGTATCTCTCATCCTTTGTGGTGGCCGCCATCATTTGCTGGAAGAAATATAAGGTTGAAATC
TTTTCTCAGCTAAATGGCAATATTGTAGGTATTGCCGTCATTTGGCGTGAACTTCTCCTCGCATTGGTATTAACTTGCCT
TGCTTGCGCATTGATTGTCTTATTATTGGATGCTATTGCGGAATATTTCCTGACCATGAAAGATATGAAAATGGATAAGG
AAGAAGTGAAGCGTGAAATGAAGGAGCAGGAAGGGAACCCAGAGGTTAAATCTAAAAGACGTGAAGTTCATATGGAAATT
CTGTCTGAACAGGTGAAATCTGATATTGAAAACTCACGCCTGATTGTTGCCAACCCCACGCATATTACGATCGGGATTTA
TTTTAAACCCGAATTGATGCCGATTCCGATGATCTCGGTGTATGAAACGAATCAGCGCGCACTGGCCGTCCGCGCCTATG
CGGAGAAGGTTGGCGTACCTGTGATCGTCGATATCAAACTGGCGCGCAGTCTTTTCAAAACCCATCGCCGTTATGATCTG
GTGAGTCTGGAAGAAATTGATGAAGTTTTACGTCTTCTGGTTTGGCTGGAAGAGGTAGAAAACGCGGGCAAAGACGTTAT
TCAGCCACAAGAAAACGAGGTACGGCATTGA

Protein sequence :
MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVSYGSFNEFMGIIKIIIADNFDQSMADYSLAVFGIGLK
YLIPFMLLCLVCSALPALLQAGFVLATEALKPNLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEI
FSQLNGNIVGIAVIWRELLLALVLTCLACALIVLLLDAIAEYFLTMKDMKMDKEEVKREMKEQEGNPEVKSKRREVHMEI
LSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIPMISVYETNQRALAVRAYAEKVGVPVIVDIKLARSLFKTHRRYDL
VSLEEIDEVLRLLVWLEEVENAGKDVIQPQENEVRH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
spaS NP_461808.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 2e-133 100
spaS YP_217806.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 4e-132 99
spaS NP_457281.1 secretory protein (associated with virulence) Virulence SPI-1 Protein 5e-133 99
spaS NP_806490.1 surface presentation of antigens protein SpaS Virulence SPI-1 Protein 5e-133 99
spaS AAS66868.1 SpaS Not tested SSR-2 Protein 5e-67 55
ECs3721 NP_311748.1 surface presentation of antigens protein SpaS Not tested LIM Protein 3e-59 54
ysaU AAS66849.1 YsaU Not tested SSR-1 Protein 4e-43 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN001921_02640 YP_008253936.1 type III secretion system protein SpaS VFG0548 Protein 7e-134 100
CFSAN001921_02640 YP_008253936.1 type III secretion system protein SpaS VFG1015 Protein 7e-52 49
CFSAN001921_02640 YP_008253936.1 type III secretion system protein SpaS VFG2452 Protein 4e-48 45