Gene Information

Name : CFSAN001921_12265 (CFSAN001921_12265)
Accession : YP_008255820.1
Strain : Salmonella enterica CFSAN001921
Genome accession: NC_021814
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 2486813 - 2487559 bp
Length : 747 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; Derived by automated computational analysis using gene prediction method:

DNA sequence :
ATGAGTTTCGTCGTCATCATTCCGGCCCGTTTTTCATCTACCCGACTGCCAGGCAAACCATTAGTGGATATTAATGGTAA
GCCCATGATTGTTCATGTCCTGGAGCGGGCGCGCGAATCTGGCGCGGAACGCATTATTGTCGCGACCGATCATGAAGACG
TGGCTCGTGCGGTAGAAGCGGCTGGCGGCGAAGTGTGCATGACGCGCGCCGATCACCAGTCCGGCACCGAACGGTTGGCG
GAAGTGGTAGAGAAGTGCGGATTCAGCGACGATACCGTTATTGTGAACGTTCAGGGCGATGAGCCGATGATCCCGGCGGT
TATTATTCGCCAGGTCGCGGAAAATCTGGCGCAGCGCCAGGTTGGCATGGCGACGCTGGCGGTGCCGATTCACAGCGCCG
AAGAAGCGTTTAACCCGAATGCGGTAAAAGTCGTGCTGGATGCTGAAGGCTATGCGCTTTACTTTTCCCGGGCGACGATT
CCCTGGGATCGCGATCGCTTTGCAAAAAGTCTGGAAACGGTAGGGGATACTTGCCTTCGTCACCTGGGCATTTATGGCTA
TCGCGCGGGGTTTATCCGCCGTTACGTGAGCTGGCAACCCAGCCCGCTGGAACATATTGAAATGCTGGAGCAACTCCGTG
TGCTGTGGTACGGCGAAAAAATTCATGTCGCCGTCGCCAAAGCGGTGCCCGGCACGGGCGTAGACACCGCCGACGACCTG
GAGCGCGTGCGCGCTGAAATGCGTTAA

Protein sequence :
MSFVVIIPARFSSTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAVPIHSAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKSLETVGDTCLRHLGIYGYRAGFIRRYVSWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKAVPGTGVDTADDL
ERVRAEMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 7e-33 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-32 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 5e-33 45