Gene Information

Name : CFSAN002069_17845 (CFSAN002069_17845)
Accession : YP_008252329.1
Strain : Salmonella enterica CFSAN002069
Genome accession: NC_021812
Putative virulence/resistance : Virulence
Product : pathogenicity island 1 effector protein SipB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3716279 - 3718060 bp
Length : 1782 bp
Strand : +
Note : cell invasion protein B; required for entry of the bacteria into the host cell; induces apoptosis in macrophages; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGGTAAATGACGCAAGTAGCATTAGCCGTAGCGGATATACCCAAAATCCGCGCCTCGCTGAGGCGGCTTTTGAAGGCGT
TCGTAAGAACACGGACTTTTTAAAAGCGGCGGATAAAGCTTTTAAAGATGTGGTGGCAACGAAAGCGGGCGACCTTAAAG
CCGGAACAAAGTCCGGCGAGAGCGCTATTAATACGGTGGGTCTAAAGCCGCCTACGGACGCCGCCCGGGAAAAACTCTCC
AGCGAAGGGCAATTGACATTACTGCTTGGCAAGTTAATGACCCTACTGGGCGATGTTTCGCTGTCTCAACTGGAGTCTCG
TCTGGCGGTATGGCAGGCGATGATTGAGTCACAAAAAGAGATGGGGATTCAGGTATCGAAAGAATTCCAGACGGCTCTGG
GAGAGGCTCAGGAGGCGACGGATCTCTATGAAGCCAGTATCAAAAAGACGGATACCGCCAAGAGTGTTTATGACGCTGCG
ACCAAAAAACTGACGCAGGCGCAAAATAAATTGCAATCGCTGGACCCGGCTGACCCCGGCTATGCACAAGCTGAAGCCGC
GGTAGAACAGGCCGGAAAAGAAGCGACAGAGGCGAAAGAGGCCTTAGATAAGGCCACGGATGCGACGGTTAAAGCAGGCA
CAGACGCCAAAGCGAAAGCCGAGAAAGCGGATAACATTCTGACCAAATTCCAGGGAACGGCTAATGCCGCCTCTCAGAAT
CAGGTTTCCCAGGGTGAGCAGGATAATCTGTCTAATGTCGCCCGCCTCACTATGCTCATGGCCATGTTTATTGAGATTGT
GGGCAAAAATACGGAAGAAAGCCTGCAAAACGATCTTGCGCTTTTCAACGCCTTGCAGGAAGGGCGTCAGGCGGAGATGG
AAAAGAAATCGGCTGAATTCCAGGAAGAGACGCGCAAAGCCGAGGAAACGAACCGCATTATGGGATGTATCGGGAAAGTC
CTCGGCGCGCTGCTAACCATTGTCAGCGTTGTGGCAGCTGTTTTTACCGGTGGGGCGAGTCTGGCGCTGGCTGCGGTGGG
ACTTGCGGTAATGGTGGCCGATGAAATTGTGAAGGCGGCGACGGGGGTGTCGTTTATTCAGCAGGCGCTAAACCCGATTA
TGGAGCATGTGCTGAAGCCATTAATGGAGCTGATTGGCAAGGCGATTACCAAAGCGCTGGAAGGATTAGGCGTCGATAAG
AAAACGGCAGAGATGGCAGGCAGCATTGTTGGTGCGATTGTTGCCGCTATTGCGATGGTAGCGGTCATTGTGGTGGTCGC
AGTTGTCGGGAAAGGCGCGGCGGCGAAACTGGGTAACGCGCTGAGCAAAATGATGGGCGAAACGATTAAGAAGTTGGTGC
CTAACGTGCTGAAACAGTTGGCGCAAAACGGCAGCAAACTCTTTACCCAGGGGATGCAACGTATTACTAGCGGCCTGGGT
AATGTGGGTAGCAAGATGGGCCTGCAAACGAATGCCTTAAGTAAAGAGCTGGTAGGTAATACCCTAAATAAAGTGGCGTT
GGGCATGGAAGTCACGAATACCGCAGCCCAGTCAGCCGGTGGTGTTGCCGAGGGCGTATTTATTAAAAATGCCAGCGAGG
CGCTTGCTGATTTTATGCTCGCCCGTTTTGCCATGGATCAGATTCAGCAGTGGCTTAAACAATCCGTAGAAATATTTGGT
GAAAACCAGAAGGTAACGGCGGAACTGCAAAAAGCCATGTCTTCTGCGGTACAGCAAAATGCGGATGCTTCGCGTTTTAT
TCTGCGCCAGAGTCGCGCATAA

Protein sequence :
MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGESAINTVGLKPPTDAAREKLS
SEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIESQKEMGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAA
TKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQN
QVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRKAEETNRIMGCIGKV
LGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAATGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDK
KTAEMAGSIVGAIVAAIAMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLG
NVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFG
ENQKVTAELQKAMSSAVQQNADASRFILRQSRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sipB NP_461806.1 translocation machinery component Virulence SPI-1 Protein 0.0 100
sipB NP_457279.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 99
sipB NP_806488.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 0.0 99
sipB YP_217804.1 cell invasion protein Virulence SPI-1 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
CFSAN002069_17845 YP_008252329.1 pathogenicity island 1 effector protein SipB VFG0546 Protein 0.0 100
CFSAN002069_17845 YP_008252329.1 pathogenicity island 1 effector protein SipB VFG0987 Protein 6e-70 43