Gene Information

Name : leuS (CFSAN002069_05600)
Accession : YP_008249960.1
Strain : Salmonella enterica CFSAN002069
Genome accession: NC_021812
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.4
Position : 1133343 - 1135925 bp
Length : 2583 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCCAAAGTACAGCTTCACTGGGATGAGAAGCGCACATTTGAAGTGAC
CGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCCTATCCTTCTGGCCGACTACACATGGGCCACGTAC
GTAACTACACCATCGGCGACGTGGTTGCCCGCTACCAGCGTATGCTGGGCAAAAACGTGCTACAGCCAATCGGCTGGGAC
GCCTTCGGCCTGCCGGCGGAAGGCGCGGCGGTGAAGAACAACACCGCGCCGGCGCCGTGGACGTACGACAACATCGCGTA
CATGAAAAACCAGCTCAAAACGCTGGGTTTTGGCTATGACTGGAGCCGTGAAATCGCGACCTGCACCCCGGAATACTACC
GTTGGGAACAGAAATTCTTCACCGAGCTGTATAAAAAAGGCCTGGTGTACAAGAAGACTTCTGCCGTTAACTGGTGCCCG
AACGATCAGACCGTTCTCGCCAACGAACAGGTGATCGACGGCTGCTGCTGGCGTTGCGACACCAAAGTTGAGCGTAAAGA
GATCCCACAGTGGTTTATCAAAATCACCGCTTACGCAGACGAGCTGTTGCGCGATCTGGATAAGCTGGACCACTGGCCTG
ATACCGTAAAAACGATGCAGCGCAACTGGATTGGCCGCTCTGAAGGCGTGGAAATCACCTTCGATGTGAAGGGTTACGAT
AACACCCTGACCGTCTATACCACCCGTCCGGATACCTTTATGGGCGCCACTTACCTGGCGGTGGCCGCCGGTCATCCGCT
GGCGCAAAAAGCGGCGGCGAACAACGCCGAGCTGGCGGCGTTCATCGACGAATGCCGTAACACCAAAGTGGCCGAAGCCG
AAATGGCGACCATGGAGAAAAAAGGCGTCGACACCGGCTATAAAGCGATTCATCCGTTAACTGGCGAAGAGATCCCGGTC
TGGGCGGCAAACTTTGTCCTGATGGAGTACGGCACTGGCGCGGTGATGGCCGTTCCGGGTCACGATCAGCGCGACTACGA
ATTTGCCTCCAAATATGGTTTGACCATCAAGCCGGTGATTCTGGCCGCTGACGGTTCCGAGCCGGATCTTTCCGAACAGG
CGCTGACCGAAAAAGGCGTGCTGTTTAACTCCGGCGAGTTCGACGGTCTGGCCTTTGAAGCGGCGTTTAACGCCATTGCC
GATAAACTGGCGGAAAAAGGCGTCGGCGAACGTAAAGTGAACTATCGTCTGCGTGACTGGGGCGTTTCCCGTCAGCGTTA
CTGGGGCGCGCCGATCCCGATGGTCACCCTGGAAGATGGCACCGTGCTGCCGACGCCGGAAGATCAACTGCCGGTTATTT
TGCCGGAAGATGTCGTCATGGACGGCATCACCAGCCCGATCAAGGCCGATCCTGAGTGGGCGAAAACTACCGTTAACGGT
ATGCCGGCGCTGCGTGAAACCGACACCTTCGACACCTTTATGGAATCGTCATGGTACTACGCGCGTTACACCTGCCCGCA
GTATCAGGAAGGAATGCTGGATTCGAAAGCGGCAAACTACTGGCTGCCAGTCGACATCTACATCGGCGGTATTGAACATG
CCATCATGCACCTGCTCTACTTCCGCTTCTTCCATAAGCTGATGCGCGATGCGGGCATGGTCACCTCTGACGAGCCGGCT
AAACAGTTGCTGTGCCAGGGCATGGTACTGGCGGATGCGTTCTATTATGTCGGCGAGAACGGCGAACGTAACTGGGTTTC
GCCAGTTGACGCTATCGTCGAGCGCGATGAAAAAGGCCGCATCGTCAAAGCAAAAGACGCAGCGGGTCATGAGCTGGTCT
ACACTGGCATGAGTAAAATGTCCAAGTCGAAAAATAACGGTATCGACCCGCAGGTAATGGTTGAACGTTATGGCGCGGAC
ACGGTACGCCTGTTTATGATGTTCGCTTCTCCGGCGGATATGACTCTGGAATGGCAGGAGTCCGGCGTAGAAGGCGCAAA
CCGCTTTATTAAACGCGTCTGGAAGCTGGTTTACGAACACACCGCTAAAGGTCCTGTCGCGGCGCTGAACGTCGATGCGC
TGAGCGAAGATCAAAAAGCGCTGCGTCGCGATGTGCATAAAACCATTGCCAAAGTGACCGATGATATCGGCCGCCGTCAG
ACGTTCAACACCGCCATTGCGGCGATCATGGAGTTGATGAACAAACTGGCGAAAGCCCCGCAGGAAGGCGAACAAGACCG
CGCACTGCTTCAGGAAGCGCTGCAGGCCGTCGTGCGTATGCTTAACCCGTTCACCCCGCACGTCTGCTTTACCTTGTGGC
AGGAACTGGGCGGCGAAGGTGATATCGACAACGCGCCGTGGCCGGTTGCCGACGAGCAGGCAATGGTGGAAAACACCACG
CTGGTTGTCGTGCAGGTTAACGGTAAAGTTCGCGGTAAGATCACCGTTGCGGTGGATGCCACCGAAGAACAGGTGCGTGA
ACGTGCAGGCCAGGAACATCTGGTGGCAAAATATCTTGATGGCGTTACCGTGCGTAAAGTGATTTACGTTCCGGGTAAAC
TCCTCAATCTGGTTGTTGGCTAA

Protein sequence :
MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVVARYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKTLGFGYDWSREIATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDKLDHWPDTVKTMQRNWIGRSEGVEITFDVKGYD
NTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNAELAAFIDECRNTKVAEAEMATMEKKGVDTGYKAIHPLTGEEIPV
WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFDGLAFEAAFNAIA
DKLAEKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
MPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVTSDEPA
KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD
TVRLFMMFASPADMTLEWQESGVEGANRFIKRVWKLVYEHTAKGPVAALNVDALSEDQKALRRDVHKTIAKVTDDIGRRQ
TFNTAIAAIMELMNKLAKAPQEGEQDRALLQEALQAVVRMLNPFTPHVCFTLWQELGGEGDIDNAPWPVADEQAMVENTT
LVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-151 42