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Name : lysS (L897_02675) Accession : YP_008242819.1 Strain : Streptococcus pyogenes HSC5 Genome accession: NC_021807 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : - COG ID : - EC number : 6.1.1.6 Position : 489267 - 490772 bp Length : 1506 bp Strand : - Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : TTGGAGGAAAATATGTCTAATCAACACATCGAAGAATTAAATGACCAACAGATTGTCCGTCGTGAAAAGATGATGGCTCT GGCTGAACAAGGAATTGATCCTTTCGGTAAACGCTTTGACCGCACAGCCAATTCTGCTGAATTAAAAGAAAAGTATGCTG ATAAAACAAAAGAAGAATTACATGAGTTAAACGAAACAGCTATTGTTGCTGGCCGCTTGATGACAAAACGTGGCAAAGGT AAGGTTGGTTTTGCTCATCTTCAAGACCGTGAAGGCCAAATCCAACTTTATGTTCGCAAGGACTCTGTTGGCGAAGACAA CTATGAAATCTTCAAAAAAGCCGATTTAGGCGACTTTATCGGCGTTGAAGGCGAAGTCATGCGTACAGACATGGGCGAGT TGTCAATCAAGGCAACCAAGTTGACTCACCTTTCTAAATCACTTCGTCCTCTTCCTGAAAAATTCCACGGATTAACTGAT ATTGAAACCATTTACCGTAAGCGTCACCTTGATTTAATTTCAAATCGTGAAAGCTTTGACCGCTTCGTGACCCGTTCCAA AATGATTTCAGAAATCCGTCGTTATTTAGACGGTCTTGATTTCCTAGAAGTAGAAACGCCTGTGCTTCATAACGAGGCTG GTGGTGCTGCTGCTCGTCCTTTCGTTACTCACCATAATGCTCAAAACATTGATATGGTGCTTCGTATCGCAACAGAACTT CATTTGAAACGTTTGATTGTTGGTGGTATGGAACGTGTCTATGAAATTGGTCGTATCTTCCGTAACGAGGGAATGGATGC TACTCATAATCCTGAGTTCACTTCTATTGAGGTCTACCAAGCCTATGCAGACTATCTTGATATCATGAACCTGACAGAAG GCATTATCCAACATGCTGCTAAAGCTGTTAAAGGTGATGGCCCTATTGATTATCAAGGAACTGAAATCCTTATCAATGAA CCTTTCAAACGTGTCCACATGGTAGATGCTATCAAGGAAGTGACAGGTGTTGATTTCTGGCCTGAAATGACTGTCGAAGA AGCTATTGCACTTGCCAAAGAAAAACAGGTCCCACTCGAAAAACACTTCACAAGTGTCGGACATATCATCAATGCTTTCT TCGAAGAATTCGTTGAAGAAACCTTGGTTCAACCAACCTTTGTCTTTGGTCATCCTGTTGAAGTATCACCTTTGGCTAAG AAGAATCCAGAAGATACCCGCTTCACCGACCGCTTCGAACTTTTCATCATGACCAAAGAATACGCCAATGCTTTCACAGA GTTGAATGATCCCATTGACCAATTATCTCGTTTTGAAGCACAAGCACAAGCTAAAGAACTTGGTGATGACGAAGCAACTG GCATTGACTACGACTTCGTTGAAGCTCTTGAATATGGTATGCCGCCAACCGGTGGACTCGGAATCGGGATTGATCGTCTT TGCATGTTATTAACAAACACAACAACAATCAGAGATGTGCTTTTATTCCCAACGATGAAACCTTAA Protein sequence : MEENMSNQHIEELNDQQIVRREKMMALAEQGIDPFGKRFDRTANSAELKEKYADKTKEELHELNETAIVAGRLMTKRGKG KVGFAHLQDREGQIQLYVRKDSVGEDNYEIFKKADLGDFIGVEGEVMRTDMGELSIKATKLTHLSKSLRPLPEKFHGLTD IETIYRKRHLDLISNRESFDRFVTRSKMISEIRRYLDGLDFLEVETPVLHNEAGGAAARPFVTHHNAQNIDMVLRIATEL HLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADYLDIMNLTEGIIQHAAKAVKGDGPIDYQGTEILINE PFKRVHMVDAIKEVTGVDFWPEMTVEEAIALAKEKQVPLEKHFTSVGHIINAFFEEFVEETLVQPTFVFGHPVEVSPLAK KNPEDTRFTDRFELFIMTKEYANAFTELNDPIDQLSRFEAQAQAKELGDDEATGIDYDFVEALEYGMPPTGGLGIGIDRL CMLLTNTTTIRDVLLFPTMKP |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 2e-105 | 47 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_008242819.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 1e-105 | 47 |
