Gene Information

Name : F382_04550 (F382_04550)
Accession : YP_008233780.1
Strain : Mannheimia haemolytica D153
Genome accession: NC_021743
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 880954 - 881709 bp
Length : 756 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; Derived by automated computational analysis using gene prediction method:

DNA sequence :
ATGAAATTCACTGTAATTATTCCTGCTCGTTACGCTTCCAGCCGTTTGCCTCGTAAGCCGTTGTTGGATATTGCAGGCAA
ACCGATGATTCAACACGTTTGGGAAAAAGCTCAGCTTGCCGGTGCAAGCCGTGTGATTATTGCCACCGATCACCCTGAAA
TTGAAGCCCTCGCTCAATCTTTTGGGGCGGAAGTCTGTATGACTTCGGAAAAACACAATTCCGGCACTGAGCGTTTGGCG
GAAGTGATCGAAAAAATGCAGATTGCCGACAGCGAAATTATTGTGAATATTCAGGGTGATGAACCGCTGATTCCACCGGT
AATTGTTACTCAGGTAGCTCAAAATTTAGATGCTTATCAAGTCAATATGGCAACACTCGGTGTGAAATTAGCGACCCGAG
AAGAGCTATTTAACCCAAATGCGGTGAAAGTGGTGGCAGACAAAAACGGAATGGCACTTTATTTTTCCCGAGCCAGCATT
CCGTTTGCCAGAGACAGTTTTCCGGATTGTGATGACAGTTTTGTTGCCGCTCAAGGTTATTTACGCCATATCGGCATTTA
CGCTTACCGAGCCGGTTTTGTGAAACAATATGTGGCGTGGCAGCCGACACAATTAGAACAGCTTGAGTCCCTTGAGCAAC
TAAGAGCCTTATGGCACGGTGAAAAAATTCATATCGAACCGGCGAAAGAAGCCCCGCAAGTGGGGGTGGATACGCCGGAA
GATTTGGAAAGAGTGCGAGCCATTTTAGCTCGTTAA

Protein sequence :
MKFTVIIPARYASSRLPRKPLLDIAGKPMIQHVWEKAQLAGASRVIIATDHPEIEALAQSFGAEVCMTSEKHNSGTERLA
EVIEKMQIADSEIIVNIQGDEPLIPPVIVTQVAQNLDAYQVNMATLGVKLATREELFNPNAVKVVADKNGMALYFSRASI
PFARDSFPDCDDSFVAAQGYLRHIGIYAYRAGFVKQYVAWQPTQLEQLESLEQLRALWHGEKIHIEPAKEAPQVGVDTPE
DLERVRAILAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-37 46
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-36 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-36 46