Gene Information

Name : smpB (F382_12990)
Accession : YP_008235400.1
Strain : Mannheimia haemolytica D153
Genome accession: NC_021743
Putative virulence/resistance : Unknown
Product : single-stranded DNA-binding protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2549553 - 2550032 bp
Length : 480 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCAAAAAAACCTAAAGTTGCATCAAATACGATTGCGTTAAATAAACGTGCCAGACACGAATATTTCATTGAAGATGA
AATTGAAGCCGGCTTAGAGCTACAGGGCTGGGAAGTCAAAGCATTGCGTGCCGGAAAAGGCAATATCAGCGATAGCTATG
TCATCTTTCGCCACGGCGAAGCCTTCTTATTCGGGGCAATGATTACGCCTTTGAATATGGCATCAACCCATATTGTCAGC
GACCCGACCCGCACCCGCAAACTTCTACTGAATAAACGTGAGTTAGACTCACTGTTCGGTAAAGTTAATCGTGAAGGTTA
TACCATTGTTGCCACCTCAATGTATTGGAAAAATGCGTGGGTGAAAGTAAAAATCGGCTTAGCCAAAGGGAAAAAACTGC
ACGATAAACGTGAAGATATTAAAGACCGTGAATGGCAAGTGGCTAAACAGCGTATTATGAAAAACGCCAATCGTGGCTAA

Protein sequence :
MAKKPKVASNTIALNKRARHEYFIEDEIEAGLELQGWEVKALRAGKGNISDSYVIFRHGEAFLFGAMITPLNMASTHIVS
DPTRTRKLLLNKRELDSLFGKVNREGYTIVATSMYWKNAWVKVKIGLAKGKKLHDKREDIKDREWQVAKQRIMKNANRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-50 68
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-22 43
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 4e-19 42