Gene Information

Name : M495_25095 (M495_25095)
Accession : YP_008232870.1
Strain :
Genome accession: NC_021742
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 11518 - 13461 bp
Length : 1944 bp
Strand : +
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGTCTAACGTTAAAAAACCCCGTGCCCGTAAAGAGCAACGCGAAGAAGCCCAGCAGTTTATCGATACCCTTCAGGGCGT
GTCCTTTCCCAATTCACGCCGGATTTATCTGCAGGGCTCACGCAACGATCTGCAGGTGCCGATGCGTGAAATCCAGCTTA
GCCCGACGCTGCTTGGCGGCGACAAAGACAACCCACAGTACCAGCCCAACGAAGCCATTCCGGTATACGACACTGCCGGT
CCTTATGGCGATCCGCAATCTGAACTTAATGTGCATACCGGCCTGGTAAAACTGCGTGCAGGCTGGATAGCTGAACGCGG
TGATACCGAACTGCTCAATGGCGTCAGTTCCGGCTTTACCCAGCAGCGCCTGGCGGATGAAGGTCTGGATCACCTGCGTT
TTGAACATCTGCCGCGGCCGCGCAAGGCGCAACCCGGCAAATGCGTCACCCAGTTGCACTACGCCCGCGCTGGCGTAATC
ACCCCTGAGATGGAGTTTATCGCCATCCGCGAAAACATGGGCCGCGAGCGTATCCGTGGCGATGTCCTGCGCCAGCAGCA
TCCAGGGCAAAGTTGGGGCGCCAATCTGCCGGAGAACATCACGCCGGAATTCGTTCGCCAGGAAGTGGCCGCTGGACGCG
CCATCATCCCCGCTAATATCAACCATCCCGAATCCGAGCCGATGATCATCGGTCGCAATTTTCTGGTGAAAGTTAACGCC
AACATCGGCAACTCGGCGGTGACCTCATCCATCGAAGAGGAGGTCGAAAAACTGGTCTGGTCCACCCGCTGGGGCGCGGA
TACGGTGATGGACCTGTCCACCGGCCGCTATATCCACGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTACCGATCG
GCACGGTGCCTATCTATCAGGCGCTGGAAAAAGTGAACGGCGTGGCGGAAAACCTGACCTGGGAAATGTTCCGCGATACG
TTACTTGAGCAGGCAGAGCAAGGCGTTGACTACTTCACCATCCACGCCGGCGTACTGTTGCGCTATGTACCGATGACCGC
CAAGCGCCTGACCGGCATCGTCTCGCGCGGCGGTTCGATCATGGCTAAATGGTGTCTGTCACACCATCAGGAAAACTTCC
TGTACCAGCACTTCCGCGAAATCTGCGAAATTTGCGCCGCCTATGACGTCTCACTGTCCCTGGGAGATGGCCTGCGCCCC
GGCTCAATTCAGGACGCCAATGATGAAGCGCAGTTCGCCGAACTGCACACGCTGGGCGAACTGACCAAAATTGCCTGGGA
ATATGACGTGCAGGTGATGATCGAAGGCCCGGGTCATGTACCGATGCAAATGATCCGTCGCAACATGACCGAAGAGTTGG
AGCATTGCCACGAAGCGCCGTTCTACACCCTTGGCCCGCTAACCACCGATATCGCCCCGGGCTATGACCACTTCACCTCC
GGCATCGGCGCCGCGATGATCGGTTGGTTCGGCTGCGCCATGCTGTGTTACGTCACGCCGAAGGAGCACCTCGGGCTGCC
GAACAAAGAAGACGTCAAACAGGGGCTGATCACCTACAAAATTGCCGCCCACGCCGCCGATTTGGCCAAAGGCCACCCGG
GTGCCCAGATCCGCGATAACGCCATGTCCAAGGCGCGTTTCGAATTCCGCTGGGAAGATCAGTTCAACCTGGCGCTCGAC
CCGGCTACCGCCCGCGCTTATCACGACGAAACCCTGCCGCAAGAGTCCGGCAAAATCGCCCACTTCTGTTCCATGTGCGG
CCCCAAATTCTGCTCGATGAAAATTTCGCAGGAAGTACGCGACTATGCCGCTGCGCAGGAAGCCGCCAAACCGATAGAAG
TACAACTCACCGGCATGGAAAAAATGTCGGCCGAGTTCCGTTCACGCGGCAGCGAGCTCTACCACAGCGCCGGCAACCTG
CAAGAGGAACTGAGCAATGACTGA

Protein sequence :
MSNVKKPRARKEQREEAQQFIDTLQGVSFPNSRRIYLQGSRNDLQVPMREIQLSPTLLGGDKDNPQYQPNEAIPVYDTAG
PYGDPQSELNVHTGLVKLRAGWIAERGDTELLNGVSSGFTQQRLADEGLDHLRFEHLPRPRKAQPGKCVTQLHYARAGVI
TPEMEFIAIRENMGRERIRGDVLRQQHPGQSWGANLPENITPEFVRQEVAAGRAIIPANINHPESEPMIIGRNFLVKVNA
NIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGVAENLTWEMFRDT
LLEQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRP
GSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTS
GIGAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALD
PATARAYHDETLPQESGKIAHFCSMCGPKFCSMKISQEVRDYAAAQEAAKPIEVQLTGMEKMSAEFRSRGSELYHSAGNL
QEELSND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68