Gene Information

Name : guaA (M495_18520)
Accession : YP_008231626.1
Strain : Serratia liquefaciens ATCC 27592
Genome accession: NC_021741
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 3875033 - 3876610 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGACAAAAAATATCCATAAGCATCGCATTCTGATTCTGGACTTTGGTTCGCAATACACCCAACTGGTCGCCCGCCGCGT
GCGCGAAATCGGCGTTTACTGCGAGCTGTGGGCCTGGGACGTTAGCGAAGAGCAAATCCGCGAATTCAATCCGAGCGGCA
TCATCCTGTCCGGCGGCCCGGAAAGCACCACCGAAACCAACAGCCCGCGTGCGCCAGAATACGTGTTCACCGCCGGTGTA
CCTGTGCTGGGCGTATGCTACGGCATGCAGACCATGGCAATGCAGCTGGGCGGCCATGTGCAAGGTTCCAACGAGCGTGA
ATTCGGTTACGCGCAGGTGGAAATTACCACCGACAGCGCACTGGTTCGCGGCATCGAAGACGCGCTGAGCCCAACCGGTA
AACCGCTGCTCGACGTGTGGATGAGCCACGGCGACAAAGTGACCGCTATCCCGTCCGACTTCGTGACCGTTGCCAGCACC
GATACCTGCCCGTTTGCCATTATGGCCAACGAAGAAAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CCGTCAGGGCCAGCGCATGCTGGAGCGTTTCGTGCTGGATATCTGCCAGTGTGAAGCCCTGTGGACCCCGGCGACCATCA
TCGAAGATGCGGTAGAGCGCATTCGTGAGCAGGTGGGCGAAGATCACGTGATCCTCGGCCTGTCCGGCGGCGTCGACTCT
TCCGTGACCGCAATGCTGCTGCATCGCGCCATCGGTAAACGCCTGACCTGCGTGTTCGTCGATAACGGCCTGCTGCGTCT
GAATGAAGCAGACCAGGTGCTGGAAATGTTTGGCGACCACTTCGGCCTGAACATCGTTCACGTGGCGGCGGAAGATCGCT
TCCTGAGCGCGTTAGCCGGCGTTGACGAACCGGAAGCCAAGCGCAAGATCATCGGCCGCGTGTTCGTTGAACTGTTCGAC
GAAGAAGCCTGCAAGCAGACTGAAGTGAAATGGCTGGCGCAGGGCACCATCTACCCGGACGTGATCGAATCCGCCGCCTC
CGCCACCGGCAAAGCGCACGTGATCAAATCGCACCACAACGTGGGTGGCCTGCCGAAAGAGATGAAGCTGGGCCTGGTCG
AGCCGCTGAAAGAGCTGTTCAAAGACGAAGTGCGCAAAATCGGTCTGGAACTGGGCCTGCCGTACGACATGCTTTACCGT
CACCCGTTCCCGGGCCCAGGTTTGGGCGTGCGCGTACTGGGCGAAGTGAAGAAAGAGTACTGCGATCTGCTGCGCCGTGC
CGATGCGATCTTCATCGAAGAGCTGCACAAAGCCGATCTGTACAACAAAGTCAGCCAGGCATTCACCGTGTTCCTGCCGG
TGCGTTCGGTTGGCGTGATGGGCGATGGCCGTAAATACGACTGGGTTGTTTCACTGCGCGCAGTGGAAACCATCGACTTT
ATGACCGCACATTGGGCGCACCTGCCGTACGATTTCCTCGGTCGCGTCTCCAACCGCATCATCAACGAAGTCAACGGCAT
TTCCCGTGTGGTTTATGACATCAGCGGTAAGCCACCGGCTACCATTGAGTGGGAATGA

Protein sequence :
MTKNIHKHRILILDFGSQYTQLVARRVREIGVYCELWAWDVSEEQIREFNPSGIILSGGPESTTETNSPRAPEYVFTAGV
PVLGVCYGMQTMAMQLGGHVQGSNEREFGYAQVEITTDSALVRGIEDALSPTGKPLLDVWMSHGDKVTAIPSDFVTVAST
DTCPFAIMANEEKRFYGVQFHPEVTHTRQGQRMLERFVLDICQCEALWTPATIIEDAVERIREQVGEDHVILGLSGGVDS
SVTAMLLHRAIGKRLTCVFVDNGLLRLNEADQVLEMFGDHFGLNIVHVAAEDRFLSALAGVDEPEAKRKIIGRVFVELFD
EEACKQTEVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-127 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-127 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-127 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 9e-112 48