Gene Information

Name : tpx (M495_13055)
Accession : YP_008230553.1
Strain : Serratia liquefaciens ATCC 27592
Genome accession: NC_021741
Putative virulence/resistance : Virulence
Product : lipid hydroperoxide peroxidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2752663 - 2753166 bp
Length : 504 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGACTCAGACAGTACATTTTCAAGGCAACCCGGTTAGCGTTGCAGGCCATCTGCCACAGTCCGGCGAACAAGCCAAAGC
CTTCTCTCTGGTTGCCAAAGACCTGTCAGATGTGGCGCTGAGCAGCTTCGCGGGTCAACGCAAAGTTCTGAACATTTTCC
CAAGCATCGATACCGGCGTTTGTGCGACTTCAGTGCGTAAATTCAACCAGTTGGCCAGCGGCCTGGATAACACCGTAGTG
TTGTGCATTTCATCCGACCTGCCGTTTGCACAGTCACGTTTCTGTGGCGCGGAAGGCCTGAGCAACGTGGTGACCCTGTC
CACTCTGCGCGGTGCAGAATTCAAACAAGCCTACGGCGTTGAAATCGCCGAGGGCCCACTGGCCGGTCTGACTGCACGTG
CGGTCGTGGTGCTGGATGGCCAGGATAACGTGTTGTACAGCGAGCTGGTGAATGAAATCACCAACGAACCAGACTATGAC
GCGGCGCTGGCTGCATTGAAGTAA

Protein sequence :
MTQTVHFQGNPVSVAGHLPQSGEQAKAFSLVAKDLSDVALSSFAGQRKVLNIFPSIDTGVCATSVRKFNQLASGLDNTVV
LCISSDLPFAQSRFCGAEGLSNVVTLSTLRGAEFKQAYGVEIAEGPLAGLTARAVVVLDGQDNVLYSELVNEITNEPDYD
AALAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 1e-34 48
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 2e-34 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 1e-34 48
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 3e-34 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_008230553.1 lipid hydroperoxide peroxidase VFG0087 Protein 4e-35 48