Gene Information

Name : M495_08115 (M495_08115)
Accession : YP_008229578.1
Strain : Serratia liquefaciens ATCC 27592
Genome accession: NC_021741
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 1736512 - 1737261 bp
Length : 750 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; Derived by automated computational analysis using gene prediction method:

DNA sequence :
ATGAGTTTCATCGCTATTATTCCAGCTCGTTATGCTTCAACCCGTTTGCCTGGGAAACCACTGGCCGATATTCACGGTAA
GCCGATGGTGGTGCACGTCATGGAACGTGCGCGCGAGTCCGGTGCCAGCCGCGTCATTGTGGCGACCGACCACCCAGCCG
TCGCCGAAGCGGTGAAAGCGGCCGGTGGTGAAGTTTGCATGACCCGGGCCGATCACAATTCGGGCACCGAACGTTTGGCT
GAAGTGATCGAGCATTATGGCTTTAATGATGACGAAATCATCGTTAACGTTCAGGGTGACGAACCTCTTATCCCTCCGGT
CATAGTACGGCAGGTGGCTGAAAACCTGGCGGGCAGCCAGGCTGGTATGGCTACCTTGGCAGTGCCGATCGACAGTGCGG
AAGAAGCCTTCAACCCCAATGCAGTTAAGGTGGTTATGGATGCGCAGGGCTATGCGCTCTACTTTTCGCGCGCCACCATT
CCGTGGGATCGTGAACGTTTCGCCCAATCCAAAGAGAGCATCGGCGACAGCCTGTTGCGGCATATCGGCATTTACGCCTA
TCGCGCCGGCTTTGTACGCCGTTATGTCACCTGGGCGCCAAGCCAACTGGAACAAATTGAGTTGCTGGAGCAGTTGCGGG
TGCTGTGGTACGGCGAAAAAATCCACGTGGCGGTTGCCAAGGCAATGCCGAGCGTGGGTGTTGATACGCCGGAAGACTTG
CAGCGTGTCCGTGACAGCATGAAAAGCTGA

Protein sequence :
MSFIAIIPARYASTRLPGKPLADIHGKPMVVHVMERARESGASRVIVATDHPAVAEAVKAAGGEVCMTRADHNSGTERLA
EVIEHYGFNDDEIIVNVQGDEPLIPPVIVRQVAENLAGSQAGMATLAVPIDSAEEAFNPNAVKVVMDAQGYALYFSRATI
PWDRERFAQSKESIGDSLLRHIGIYAYRAGFVRRYVTWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAMPSVGVDTPEDL
QRVRDSMKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-28 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-28 46
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 3e-29 46