Gene Information

Name : leuS (M495_05390)
Accession : YP_008229044.1
Strain : Serratia liquefaciens ATCC 27592
Genome accession: NC_021741
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.4
Position : 1156403 - 1158985 bp
Length : 2583 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATACCGTCCAGAAGACATAGAATCGAACGTACAGCTTCACTGGGAAGAGAAGCAAACTTTCAAAGTTAC
CGAAGATGCGAGCAAGGAAAAGTATTACTGCCTATCCATGCTGCCGTACCCATCAGGCCGTCTGCACATGGGGCACGTTC
GTAACTACACTATCGGCGACGTGATCTCGCGCTACCAGCGCATGTTAGGTAAAAACGTGCTACAGCCCATCGGCTGGGAT
GCGTTCGGCCTGCCGGCGGAAGGCGCTGCGGTTAAAAACAACACCGCACCGGCTCCGTGGACCTACGACAATATCGAATA
CATGAAGAACCAGCTGAAACTGCTGGGTTTCGGCTATGACTGGGATCGCGAGATCGCCACCTGCGATCCGGACTACTACC
GTTGGGAACAGTGGTTCTTCACCAAGCTGTACGAAAAAGGCCTGGTCTACAAGAAGACTTCCGCGGTGAACTGGTGCCCA
CACGATCTGACCGTGCTGGCCAACGAACAGGTGATCGACGGCTGCTGCTGGCGCTGCGACACCAAGGTTGAGCGTAAAGA
GATCCCTCAGTGGTTTATCAAAATCACCGACTACGCCGATCAGCTGCTCAACGATCTGGACACGCTGGAAAGCTGGCCAG
AACAGGTGAAAACCATGCAGCGCAACTGGATTGGCCGTTCCGAAGGGGTGGATATCACCTTTGACGTAGCGGGCAGCGAC
GAAAAGCTGACGGTTTACACCACCCGTCCTGACACCTTTATGGGCGCGACCTACGTGGCCGTAGCCGCAGGTCACCCATT
GGCGCAGCAAGGCGCGGTGAACAACCCGGCGCTGGCTGAATTTATCGAAGAGTGCCGCAACACCAAAGTGGCCGAAGCCG
AAATGGCGACGATGGAGAAAAAGGGCATGCCGACCGGCCTGTTCGCCATCCATCCGCTGTCCGGCGAGCAAGTGCCAATT
TGGGTCGCCAACTTTGTGCTGATGGAATACGGCACCGGCGCGGTGATGGCGGTTCCGGCTCACGATCAGCGCGACTGGGA
ATTCGCCACCAAATACGGCCTGCCAATCAAACCGGTCGTTCTGGCCCTCGACGGCAGCCAACCGGATGTACAAGCCGAAG
CGATGACCGAGAAAGGCACGCTGTTCAACTCCGGCGAGTTTGACAGTCTGGATCACCAAGACGGTTTCAACGCCATTGCC
GACAAACTGGTCGCCAAAGGCGTTGGTCAGCGCAAGGTTAACTACCGTCTGCGCGACTGGGGCGTTTCCCGCCAACGTTA
TTGGGGCGCACCAATCCCGATGGTCACGCTGGAAGACGGTACCGTGATGCCAACTCCAGAAGACCAGCTGCCGGTGATCC
TGCCGGAAGACGTGGTGATGGATGGCATTACCAGCCCGATCAAAGCCGATCCTGAGTGGGCGAAAACCACCGTTAACGGC
CAACCGGCGCTGCGCGAAACCGACACCTTCGACACCTTTATGGAGTCGTCCTGGTACTACGCGCGCTATACCTGCCCGCA
GTACGACCAGGGGATGCTGGATCCAGCCGCTGCCAACTACTGGCTGCCGGTCGATCAGTATGTCGGCGGCATCGAACACG
CCATCATGCACCTGATGTATTTCCGCTTCTTCCACAAGCTGCTGCGTGACGCTGGCCTGGTCGACTCCGACGAGCCGGCA
AAACGCCTGCTGTGCCAGGGCATGGTGCTGGCAGACGCCTTCTATTACACCGGCAACAGCGGCGAACGCGTCTGGGTTTC
CCCGGTCGACGCCAACGTTGAACGTGATGACAAAGGCCGCATTATCAAAGCCACCGATCCACAAGGTCGTGAACTGGTCT
ATGCTGGCATGAGCAAAATGTCGAAGTCGAAAAACAACGGCATCGACCCGCAGGTGATGGTTGAGAAATACGGCGCAGAT
ACCGTCCGTCTGTTCATGATGTTTGCTTCACCGGCAGAAATGACGCTGGAATGGCAGGAATCCGGCGTAGAAGGGGCAAA
CCGCTTCCTGAAACGCGTGTGGAAACTGGCCTACGAACACCTGGAAAAAGGCGCCGTTCAGCCGCTGAACGTGGCAACGC
TGAGCGAAGATCAGAAAGCGCTGCGCCGCGATCTGCACAAAACCATTGCCAAAGTGACCGACGATATCGGCCGCCGTCAG
ACCTTCAACACCGCGATTGCCGCCGTGATGGAACTGATGAACAAGCTGGCCCGTGCACCGCAAGAGAGCGAGCAAGATCG
CGCCCTGCTGCAGGAAGCGCTGTTGGCAGTCGTTCGCATGCTGTATCCGTTCACTCCGCACGTGTGCTTCTCACTGTGGC
AGGCGCTGGGCGGTGAAGGCGATGTGGATACCGCAGCCTGGCCGCAAGCCGACGAGCAGGCTATGGTCGAAGACTCCAAG
CTGGTGGTGGTGCAGGTCAACGGTAAGGTTCGCGCTAAAATCACCGTGGCTGCCGATGCAACCGAAGAGCAGGTACGTGC
GCGTGCCGCTGAGGAGCATCTGGTCGCTAAATATCTGGACGGGGTCACGGTTCGTAAAGTGATCTATGTTCCGGGCAAAT
TGCTTAACCTGGTTGTGGGTTAA

Protein sequence :
MQEQYRPEDIESNVQLHWEEKQTFKVTEDASKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIEYMKNQLKLLGFGYDWDREIATCDPDYYRWEQWFFTKLYEKGLVYKKTSAVNWCP
HDLTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITDYADQLLNDLDTLESWPEQVKTMQRNWIGRSEGVDITFDVAGSD
EKLTVYTTRPDTFMGATYVAVAAGHPLAQQGAVNNPALAEFIEECRNTKVAEAEMATMEKKGMPTGLFAIHPLSGEQVPI
WVANFVLMEYGTGAVMAVPAHDQRDWEFATKYGLPIKPVVLALDGSQPDVQAEAMTEKGTLFNSGEFDSLDHQDGFNAIA
DKLVAKGVGQRKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
QPALRETDTFDTFMESSWYYARYTCPQYDQGMLDPAAANYWLPVDQYVGGIEHAIMHLMYFRFFHKLLRDAGLVDSDEPA
KRLLCQGMVLADAFYYTGNSGERVWVSPVDANVERDDKGRIIKATDPQGRELVYAGMSKMSKSKNNGIDPQVMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGANRFLKRVWKLAYEHLEKGAVQPLNVATLSEDQKALRRDLHKTIAKVTDDIGRRQ
TFNTAIAAVMELMNKLARAPQESEQDRALLQEALLAVVRMLYPFTPHVCFSLWQALGGEGDVDTAAWPQADEQAMVEDSK
LVVVQVNGKVRAKITVAADATEEQVRARAAEEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-158 43