Gene Information

Name : M943_15745 (M943_15745)
Accession : YP_008227147.1
Strain : Mycobacterium tuberculosis EAI5
Genome accession: NC_021740
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : -
COG ID : -
EC number : 1.17.4.1
Position : 3398512 - 3400689 bp
Length : 2178 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
GTGCCACCAACCGTCATTGCAGAGCCTGTAGCCTCCGGCGCGCACGCCTCTTACTCTGGGGGGCCGGGCGAAACGGACTA
TCACGCGCTGAACGCGATGCTGAACCTGTACGACGCGGACGGCAAGATCCAGTTCGACAAGGATCGGGAAGCAGCCCACC
AGTACTTTTTGCAGCATGTCAATCAGAACACGGTCTTCTTCCATAATCAGGACGAGAAGCTCGACTACCTGATCCGCGAG
AATTACTACGAGCGTGAGGTTCTCGACCAGTACTCGCGCAACTTCGTCAAGACGCTGCTAGACCGCGCCTACGCCAAAAA
GTTCCGGTTTCCGACGTTTTTGGGTGCGTTCAAGTACTACACCTCCTACACGCTGAAAACCTTTGACGGGAAGCGCTATC
TGGAGCGCTTCGAGGACCGCGTGGTCATGGTGGCGCTAACGTTGGCCGCCGGCGATACCGCACTTGCCGAGCTGCTGGTC
GACGAGATCATCGACGGCCGCTTCCAGCCCGCCACACCGACGTTTTTGAATTCTGGCAAGAAGCAGCGCGGGGAGCCCGT
GAGCTGTTTTTTGCTTCGCGTCGAAGACAACATGGAGTCGATCGGACGGTCGATCAACTCCGCGCTGCAGCTATCCAAGC
GTGGCGGGGGAGTGGCGTTGCTGCTGACCAACATTCGCGAGCACGGCGCGCCGATCAAGAACATCGAGAACCAGTCCTCG
GGCGTCATCCCCATCATGAAGTTGCTGGAGGATGCGTTCTCCTACGCCAACCAGCTGGGCGCTCGTCAAGGTGCCGGCGC
GGTGTACCTGCACGCCCATCACCCCGACATCTACCGATTCCTGGACACCAAGCGTGAGAACGCCGACGAGAAGATCCGGA
TCAAGACGCTGAGTCTGGGGGTGGTGATCCCCGACATCACCTTCGAGTTGGCCAAGCGCAACGATGACATGTACCTGTTC
TCGCCCTACGATGTCGAGCGGGTCTACGGTGTGCCGTTCGCTGACATCTCGGTCACCGAGAAGTACTACGAAATGGTCGA
TGACGCGCGCATCCGCAAGACCAAGATCAAGGCACGGGAGTTCTTCCAGACGCTGGCCGAGCTGCAGTTCGAGTCCGGCT
ACCCCTATATCATGTTCGAAGACACCGTCAATCGCGCTAATCCAATTGATGGCAAGATCACGCACAGCAACCTGTGCTCG
GAGATCCTGCAAGTGTCTACGCCGTCATTGTTCAACGAGGACTTGTCGTATGCCAAAGTGGGCAAAGACATTTCGTGCAA
CCTGGGGTCGCTGAACATCGCCAAGACGATGGACTCGCCGGACTTCGCGCAGACGATCGAGGTGGCGATCCGCGCGTTGA
CCGCGGTGAGCGACCAAACCCATATCAAGTCGGTGCCCTCAATCGAGCAGGGCAACAACGACTCCCACGCGATCGGGCTA
GGACAGATGAACCTGCACGGCTACCTGGCCCGGGAACGCATCTTCTACGGATCCGACGAAGGCATCGACTTCACCAACAT
CTACTTCTATACGGTGCTGTATCACGCGTTGCGGGCATCCAACCGCATCGCGATCGAACGCGGCACGCACTTCAAGGGTT
TCGAGCGGTCCAAGTACGCGTCCGGGGAATTCTTCGACAAGTACACCGACCAGATTTGGGAGCCGAAGACCCAGAAGGTA
CGCCAGCTGTTCGCCGACGCCGGCATCCGCATCCCAACGCAGGACGACTGGCGTCGGCTCAAGGAGTCGGTGCAAGCGCA
CGGCATCTACAACCAGAACCTGCAGGCGGTGCCGCCGACCGGGTCGATTTCCTACATCAACCATTCGACGTCGTCGATTC
ACCCGATCGTGTCGAAGGTCGAGATCCGCAAGGAAGGCAAGATCGGGCGGGTCTACTACCCGGCGCCGTATATGACCAAC
GACAACCTGGAGTACTACGAAGACGCCTACGAGATCGGTTACGAGAAGATCATCGACACCTACGCGGCGGCCACCCAGCA
TGTGGATCAAGGGCTTTCGCTGACGTTGTTCTTCAAAGACACCGCCACCACCCGCGACGTGAACAAGGCGCAGATTTACG
CCTGGCGCAAGGGGATCAAGACGCTGTACTACATCCGGCTGCGGCAGATGGCGTTGGAGGGCACCGAGGTCGAGGGTTGC
GTGTCCTGCATGCTGTAG

Protein sequence :
MPPTVIAEPVASGAHASYSGGPGETDYHALNAMLNLYDADGKIQFDKDREAAHQYFLQHVNQNTVFFHNQDEKLDYLIRE
NYYEREVLDQYSRNFVKTLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTALAELLV
DEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRVEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSS
GVIPIMKLLEDAFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKRNDDMYLF
SPYDVERVYGVPFADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGKITHSNLCS
EILQVSTPSLFNEDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRALTAVSDQTHIKSVPSIEQGNNDSHAIGL
GQMNLHGYLARERIFYGSDEGIDFTNIYFYTVLYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTDQIWEPKTQKV
RQLFADAGIRIPTQDDWRRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMTN
DNLEYYEDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGC
VSCML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 79