Gene Information

Name : M943_10270 (M943_10270)
Accession : YP_008226078.1
Strain : Mycobacterium tuberculosis EAI5
Genome accession: NC_021740
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 1.17.4.1
Position : 2218802 - 2219770 bp
Length : 969 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; Derived by automated computational analysis using gene prediction me

DNA sequence :
ATGACCGGCAAGCTCGTTGAGCGGGTGCACGCAATCAATTGGAACCGGTTGCTCGATGCTAAAGATTTGCAGGTCTGGGA
ACGTTTGACCGGTAACTTTTGGTTGCCGGAAAAGATTCCGCTCTCCAACGACCTGGCATCTTGGCAAACGTTGAGTTCCA
CCGAGCAGCAGACGACGATCCGGGTGTTCACCGGCTTGACCCTGCTCGACACCGCGCAGGCGACGGTGGGAGCAGTGGCC
ATGATCGACGACGCGGTCACCCCCCACGAAGAGGCGGTCCTGACCAACATGGCGTTCATGGAGTCAGTGCACGCCAAGAG
CTACAGCTCGATCTTCTCGACCCTGTGCTCGACCAAGCAGATCGACGATGCCTTCGACTGGTCGGAACAGAACCCTTACC
TGCAGCGAAAAGCGCAGATCATCGTCGACTACTACCGCGGTGACGACGCGCTCAAGCGCAAAGCATCGTCGGTAATGCTG
GAGTCCTTCCTGTTCTACTCCGGCTTCTACCTGCCCATGTACTGGTCGTCGCGGGGTAAGCTCACCAACACCGCCGATCT
GATCCGGCTGATCATCCGAGATGAAGCCGTCCACGGCTACTACATCGGCTACAAATGTCAACGAGGTTTGGCCGACCTGA
CCGACGCCGAGCGGGCCGACCACCGCGAATACACCTGCGAGCTGCTGCACACGCTCTACGCGAACGAGATCGACTATGCG
CACGACTTGTACGACGAGTTGGGCTGGACCGACGACGTTTTGCCCTACATGCGTTACAACGCCAACAAGGCGCTAGCCAA
CCTGGGATACCAGCCTGCATTCGATCGTGACACCTGCCAGGTGAACCCGGCCGTGCGCGCAGCTCTCGACCCCGGTGCAG
GGGAGAACCACGACTTTTTCTCCGGCTCCGGAAGCTCATACGTAATGGGCACCCACCAACCCACCACCGACACCGACTGG
GACTTCTAA

Protein sequence :
MTGKLVERVHAINWNRLLDAKDLQVWERLTGNFWLPEKIPLSNDLASWQTLSSTEQQTTIRVFTGLTLLDTAQATVGAVA
MIDDAVTPHEEAVLTNMAFMESVHAKSYSSIFSTLCSTKQIDDAFDWSEQNPYLQRKAQIIVDYYRGDDALKRKASSVML
ESFLFYSGFYLPMYWSSRGKLTNTADLIRLIIRDEAVHGYYIGYKCQRGLADLTDAERADHREYTCELLHTLYANEIDYA
HDLYDELGWTDDVLPYMRYNANKALANLGYQPAFDRDTCQVNPAVRAALDPGAGENHDFFSGSGSSYVMGTHQPTTDTDW
DF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 5e-102 63