Gene Information

Name : M943_09580 (M943_09580)
Accession : YP_008225945.1
Strain : Mycobacterium tuberculosis EAI5
Genome accession: NC_021740
Putative virulence/resistance : Unknown
Product : inosine 5'-monophosphate dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.1.1.205
Position : 2086840 - 2088279 bp
Length : 1440 bp
Strand : -
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
GTGATGAGATTTCTAGACGGGCACCCACCCGGGTACGACCTGACATACAACGACGTGTTCATCGTTCCGAACCGATCCGA
GGTCGCGTCGCGCTTCGACGTCGATTTGTCCACCGCCGACGGCTCGGGCACCACCATTCCGGTAGTGGTCGCCAATATGA
CCGCGGTAGCCGGGCGGCGGATGGCCGAGACGGTCGCCCGCCGCGGTGGCATCGTAATCCTGCCGCAGGATCTGCCGATC
CCGGCGGTAAAGCAGACGGTGGCGTTCGTCAAAAGCCGGGACCTGGTGCTCGACACCCCAGTGACGCTGGCACCCGACGA
TTCGGTGTCCGACGCCATGGCGCTCATCCACAAGCGCGCACATGGCGTCGCGGTGGTCATCCTCGAGGGTCGCCCGATCG
GATTGGTGCGCGAATCGTCCTGCCTGGGCGTGGATCGCTTCACCCGGGTGCGCGATATCGCCGTGACGGACTATGTGACC
GCTCCAGCGGGAACCGAGCCACGCAAGATCTTCGACCTGCTGGAGCACGCCCCGGTCGACGTTGCGGTGCTGACCGACGC
CGACGGCACGTTGGCGGGAGTGCTAAGCCGCACCGGGGCTATCCGCGCCGGTATCTACACCCCGGCCACCGATAGCGCGG
GCCGGCTGCGGATCGGCGCGGCCGTCGGCATCAACGGCGACGTGGGCGCTAAGGCCCGAGCGCTCGCCGAAGCCGGCGTC
GACGTGCTAGTCATCGACACCGCACACGGACACCAGGTCAAGACCTTGGACGCGATCAAGGCGGTCTCGGCACTGGACTT
GGGTTTGCCGCTGGCGGCGGGAAACGTGGTGTCGGCGGAGGGCACCCGGGATCTGCTGAAAGCCGGGGCGAACGTCGTCA
AGGTCGGTGTCGGCCCCGGCGCCATGTGCACCACCCGAATGATGACCGGTGTCGGCCGCCCGCAGTTCTCCGCTGTGCTC
GAATGCGCTTCTGCGGCAAGGCAGCTCGGTGGTCATATCTGGGCCGACGGCGGGATCCGGCATCCACGCGACGTGGCTCT
GGCGCTGGCCGCCGGCGCCTCGAACGTGATGATCGGATCGTGGTTCGCCGGCACCTACGAATCCCCCGGAGACCTGATGC
GTGACCGCGACGATCAGCCGTACAAGGAGAGCTACGGCATGGCATCCAAGCGGGCGGTGGTGGCCCGGACCGGCGCGGAC
AACCCGTTCGACCGAGCTCGTAAGGCGTTGTTCGAGGAAGGCATCTCGACGTCGCGGATGGGCCTTGACCCCGACCGCGG
AGGTGTGGAGGACCTAATTGACCACATAACTTCTGGCGTGCGCAGCACCTGCACCTATGTGGGTGCCTCGAACCTGGCGG
AGCTGCATGAGCGGGCCGTGGTGGGCGTGCAGTCGGGAGCGGGCTTTGCCGAGGGCCATCCGCTGCCCGCCGGCTGGTGA

Protein sequence :
MMRFLDGHPPGYDLTYNDVFIVPNRSEVASRFDVDLSTADGSGTTIPVVVANMTAVAGRRMAETVARRGGIVILPQDLPI
PAVKQTVAFVKSRDLVLDTPVTLAPDDSVSDAMALIHKRAHGVAVVILEGRPIGLVRESSCLGVDRFTRVRDIAVTDYVT
APAGTEPRKIFDLLEHAPVDVAVLTDADGTLAGVLSRTGAIRAGIYTPATDSAGRLRIGAAVGINGDVGAKARALAEAGV
DVLVIDTAHGHQVKTLDAIKAVSALDLGLPLAAGNVVSAEGTRDLLKAGANVVKVGVGPGAMCTTRMMTGVGRPQFSAVL
ECASAARQLGGHIWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDRDDQPYKESYGMASKRAVVARTGAD
NPFDRARKALFEEGISTSRMGLDPDRGGVEDLIDHITSGVRSTCTYVGASNLAELHERAVVGVQSGAGFAEGHPLPAGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 4e-132 58
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 4e-132 58
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 3e-132 58
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-132 58