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Name : guaA (J451_01515) Accession : YP_008221706.1 Strain : Mannheimia haemolytica D174 Genome accession: NC_021739 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : - COG ID : - EC number : 6.3.5.2 Position : 266673 - 268244 bp Length : 1572 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+. DNA sequence : ATGACAAACATCCACCACCACAAAATTTTAATTTTAGACTTCGGTTCACAATATACTCAGCTTATCGCACGCCGTGTGCG GGAGATTGGGGTTTACTGCGAGCTTTGGGCTTGGGACGTAACGGAAGAGCAGATCCGTGAATTTAACCCAACGGGGATTA TTCTTTCAGGAGGTCCTGAAAGCACCACTGAGGAAAACAGCCCACGAGCGCCGGAGTATGTGTTTAACGCTGGTCTGCCA GTGCTGGGCATTTGCTACGGAATGCAGACAATGGCGATGCAGTTGGGCGGTTTAACCGAAACGTCCGACCACCGTGAATT TGGCTATGCCTCGGTGGCTCTCAAATCTGCCGATCAACTTTTTGCAAATTTAAACGATGATTTGACCGCTTGCGAGCCAA AATTGGACGTGTGGATGAGTCACGGCGACAAAGTCACCAAATTACCACCGCACTTTACCATCACAGGCGTTACCCCAACC TGCCCGATTGCCGCGATGTCGGACGAAAGCCGCCGTTTCTATGGCGTGCAGTTCCACCCCGAAGTGACCCACACCAAACA AGGCTTGGCGTTGCTGAAAAACTTCGTGGTCGGCATTTGCGGCTGTGAAACGAACTGGACGGCAGAAAACATCATTGAAG ATGCGGTGAAACGCATTCGTGAGCAAGTGGGCGATGACGAGGTGATTTTAGGTTTGTCGGGCGGGGTGGATTCCTCCGTC ACCGCCTTGCTATTACATCGTGCTATCGGTAAAAACCTGCACTGCGTATTTGTGGATAACGGCTTGCTCCGCTTGAACGA AGGCGATCAAGTCATGGAAATGTTCGGCAACAAATTCGGTTTGAACATTGTGCGAGTGAATGCCGAAGACCGTTTCTTAG AAGCGTTAAAAGGCTTAGACGAACCGGAAGCTAAACGCAAAACCATTGGTAAAGTGTTTGTGGACGTGTTTGATGACGAA AGCAAAAAACTTAGCTCGGTCAAATGGCTTGCACAAGGCACGATCTACCCTGATGTGATTGAATCCGCCGCCAGCAAAAC CGGCAAAGCCCACGTGATTAAATCACACCATAACGTTGGCGGCTTGCCGGATTATATGAAGCTCGGCTTAGTCGAACCGT TGCGTGAATTGTTTAAAGACGAAGTGCGCAAAATCGGCTTGGCACTCGGCTTACCGGCTGAAATGCTCAACCGCCACCCG TTCCCCGGCCCGGGCTTAGGCGTGCGTGTGCTGGGCGAAATCAAAAAAGAGTACTGCGATTTACTGCGTAAAGCCGATGC GATCTTCATCGAAGAACTGCACAAAGCCGGCTGGTACTACAAAGTCAGCCAAGCTTTCACGGTATTCTTGCCGGTGAAAT CGGTGGGCGTAATGGGCGATGGACGCAAATATGACTGGGTCGTCAGCCTGCGTGCGGTGGAAACCATCGACTTTATGACC GCTCACTGGGCGCACTTGCCGTATGATCTATTAGGCAAAATCTCCAACCGCATTATTAACGAAGTGAACGGTATTTCCCG TGTGGTGTATGACGTGAGCGGAAAACCACCGGCAACCATTGAGTGGGAATAA Protein sequence : MTNIHHHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPTGIILSGGPESTTEENSPRAPEYVFNAGLP VLGICYGMQTMAMQLGGLTETSDHREFGYASVALKSADQLFANLNDDLTACEPKLDVWMSHGDKVTKLPPHFTITGVTPT CPIAAMSDESRRFYGVQFHPEVTHTKQGLALLKNFVVGICGCETNWTAENIIEDAVKRIREQVGDDEVILGLSGGVDSSV TALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGNKFGLNIVRVNAEDRFLEALKGLDEPEAKRKTIGKVFVDVFDDE SKKLSSVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHP FPGPGLGVRVLGEIKKEYCDLLRKADAIFIEELHKAGWYYKVSQAFTVFLPVKSVGVMGDGRKYDWVVSLRAVETIDFMT AHWAHLPYDLLGKISNRIINEVNGISRVVYDVSGKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-130 | 54 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-130 | 54 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 1e-130 | 54 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 3e-110 | 48 |
