Gene Information

Name : leuS (J450_11580)
Accession : YP_008221301.1
Strain : Mannheimia haemolytica D171
Genome accession: NC_021738
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.4
Position : 2391663 - 2394248 bp
Length : 2586 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAACAGCAGTATAACCCAAGTGAGATTGAACCTAAGGTTCAGCGTTATTGGGCAGAAAATAAAGTTTTTAAAGCAGT
TAAAGACGTTACCAAAGAGAAATACTATTGCCTTTCAATGTTGCCTTATCCGTCAGGTAAGCTACATATGGGGCACGTTC
GTAACTACACCATTGGTGATGTAGTGTCTCGTTATCAGCGTATGATCGGTAAAAATGTATTACAGCCGATGGGTTGGGAC
GCTTTCGGTTTACCGGCGGAAGGTGCTGCGGTGAAAAATAATACCGCACCGGCAAAATGGACTTACGAAAACATCGAATA
TATGAAAGGTCAGCTTAAAATGTTGGGCTTCTCTTATGACTGGGATCGTGAAGTCACCACTTGCCGTCCGGAATACTACA
AATGGGAGCAATGGTTCTTCACAGAACTTTATAAAAAAGGCTTAGTGTATAAAAAAACCTCAACCGTAAACTGGTGTCCG
AATGATGAAACTGTGCTTGCCAACGAGCAAGTTCACGAAGGTTGTTGCTGGCGTTGTGACACCCCAGTGGAACAGCGTGA
AATTCCACAATGGTTTATCAAAATCACTGACTATGCTGAAGAATTACTCAATCAGTTAGATAATCTCCCACAGTGGCCGG
ATCAAGTAAAAACCATGCAACGCAACTGGATCGGTCGTTCCGAAGGGGTAGAAATCACCTTTAAAATTGCCGGTTCAAAC
GTAGAATTACCGGTTTACACTACCCGTCCGGATACCTTCTTCGGCGTAAGCTATGTGGCGATTGCTGCGGCTCACCCATT
AGCAGAATTAGCTGCACAAAATAACCCGGCATTGGCTGAATTTATCCGTGAAGCGAAAAACACCAAAGTGGCAGAAGCAG
AATTAGCCACCATGGAGAAAAAAGGAATGGCAACCGGCTTGTTCGCCATTCACCCGTTAACAGGAAAAGAAGTACCGGTT
TGGGTTGCTAACTTTGTGTTAATGCACTACGGTACAGGTGCGGTAATGGCGGTTCCGGCTCACGATGAGCGTGACTTTGA
ATTTGCACAAAAATACGATTTGCAAATTAATCAGGTAATTCAACCGCTTGATGGCTCAGAGTGGGATTTCAGCAAAGCCG
CTTACACCGAACACGGTAAATTAATCAACTCTGCCGAGTTTGACGGCTTGGAATTTGATGTGGCTTTCACTGCGATTGCC
GATAAATTAGAGGCAATGGGCGTAGGTAAACGCCAAGTGAATTTCCGTCTGCGTGACTGGGGTGTTTCTCGTCAACGTTA
TTGGGGTGCACCAATCCCAATGATGACCACAGAAGAGGGCGAAGTGGTTACCGTTCCATTACAAGATTTACCGGTGATTC
TCCCTGAAGATGTGGTAATGAACGGCGTGCAAAGCCCAATCAAAGCCGACCCAGAGTGGGCGAAAACCACTTACAACGGC
AAACCGGCATTGCGTGAAACCGATACTTTCGATACCTTTATGGAGTCCTCTTGGTATTATGCACGTTATACTTGCCCACA
ATATCACGAAGGAATGTTAGATTCAGACGAGGCAAACTACTGGCTACCGGTCGATCAATATATCGGCGGTATTGAACACG
CCACAATGCACTTGCTCTACTTCCGTTTCTTCCATAAATTGTTGCGTGATGCGGGTATTTTAAATTCGGACGAACCGGCG
ACTAAACTGTTATGCCAAGGTATGGTGCTTGCCGATGCGTTCTACTACACCAGCCCAACTAACGAGCGTATTTGGGTCAG
CCCGACACAAGTCACCTTAGAACGTGATGAGAAAGGTCGTATCATCAAAGCAACCGATCCACAAAGGCGTGAGCTGGTTC
ACAGCGGTATGACTAAAATGTCGAAATCAAAGAACAACGGTATCGATCCGCAAGAAATGGTGGAAAAATATGGTGCTGAC
ACAGTTCGCTTGTTTATGATGTTTGCCTCCCCTGCGGAAATGACATTAGAATGGCAAGAATCCGGCGTTGAAGGGGCAAA
ACGTTTCTTAGGTCGTGTTTGGAATTTAGTTTATAGCTATGCCCAAAATCCGGCAACGACTGCATTAGATGTGAATGCCT
TAGACAAGGATCAAAAAGAACTTCGCCGTGATGTACACAAAACGATTGCTAAGGTGAGTGATGATATTGGTCGTCGTCAA
ACCTTCAATACAGCGATTGCTGCGGTGATGGAATTGATGAACAAGCTCACCAAAGCCCCACTTGAAACCGAACAAGATAA
AGCCGTAATGGCAGAAGCTTTAAGTGCGGTGGTGCGTATGCTTTACCCAATCACGCCACATATCTGCTTTGAGTTATGGC
AAGTGTTAGGTAATGAACAAACCATCGATTTTGCCCCTTGGGTACAAGCCGATGAATCCGCAATGGTGGAAGATGAAAAA
TTAGTGGTAGTACAGGTCAACGGAAAAGTGCGTGGCAAAATCACTGTTTCAGCTACTGCTACGGAAGATGAAGTTAAAGC
TATCGCTAAAGCCGATCCAAACGTTGCTAAATTCTTAGATGGTCAGCAGATTGTAAAAGAAATCTACGTTCCATTTAAAA
TGTTGAGCTTTGCGGTTAAGGCGTAA

Protein sequence :
MQQQYNPSEIEPKVQRYWAENKVFKAVKDVTKEKYYCLSMLPYPSGKLHMGHVRNYTIGDVVSRYQRMIGKNVLQPMGWD
AFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDREVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP
NDETVLANEQVHEGCCWRCDTPVEQREIPQWFIKITDYAEELLNQLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSN
VELPVYTTRPDTFFGVSYVAIAAAHPLAELAAQNNPALAEFIREAKNTKVAEAELATMEKKGMATGLFAIHPLTGKEVPV
WVANFVLMHYGTGAVMAVPAHDERDFEFAQKYDLQINQVIQPLDGSEWDFSKAAYTEHGKLINSAEFDGLEFDVAFTAIA
DKLEAMGVGKRQVNFRLRDWGVSRQRYWGAPIPMMTTEEGEVVTVPLQDLPVILPEDVVMNGVQSPIKADPEWAKTTYNG
KPALRETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGILNSDEPA
TKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLERDEKGRIIKATDPQRRELVHSGMTKMSKSKNNGIDPQEMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYSYAQNPATTALDVNALDKDQKELRRDVHKTIAKVSDDIGRRQ
TFNTAIAAVMELMNKLTKAPLETEQDKAVMAEALSAVVRMLYPITPHICFELWQVLGNEQTIDFAPWVQADESAMVEDEK
LVVVQVNGKVRGKITVSATATEDEVKAIAKADPNVAKFLDGQQIVKEIYVPFKMLSFAVKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-156 42