Gene Information

Name : LOCK919_2738 (LOCK919_2738)
Accession : YP_008201233.1
Strain : Lactobacillus casei LOCK919
Genome accession: NC_021721
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence ClcC/MecB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2683246 - 2685753 bp
Length : 2508 bp
Strand : -
Note : -

DNA sequence :
ATGGACAACTTATTTACCCCTAGTGCTAAAAATGTATTGCTTTTAGCCCAGGAACAAGCGAAGTACTTCCATCATCATGC
TGTTGGGACAGAACATTTGCTCATGGCACTGGTCATGGAAAAAGATGGTATCGCTGGTAAGACGCTGCGTCAGTTAGGGG
TCACTGAAAATGATGTCCATGACGAGATCGAGCGCTTCACAGGGTATGGGACTGTTGATGCCGCTGGTCAAGCTAGTGAT
AGTTATTTGCCTTACTCACCAAAAGGTAAAGAAATTTTGGCGTTTGCGGGTGACGAAGCAAAACGGTTAGGTGCTTTAAA
GATCGGTACCGAGCACGTTTTGCTTGGCTTGCTACGTGAAGATGACATCTTGGCAGCACGGATTTTGCAAAACCTTGGTC
TCAGTCTTTCGAAGACGCGTCAAATGGTCTTCAAGAAGATGGGGATTGCGGACACTGCAGCAAAGCGTCGTCCAATGGCA
CGTGGCGGTGCTCGTCAAGATGGACAAGGTACGCCAACGCTAGATGGTTTGGCGCGGGATTTGACCCAAATGGCGCGCGA
GAATCGGATGGATCCGGTTGTTGGGCGTGACAAAGAAGTACGCCGGCTGATCCAGATTCTGGCACGGCGGACAAAGAACA
ACCCTGTACTGATTGGCGAACCTGGTGTTGGTAAAACTGCAATTGCAGAAGGCTTTGCTGAAAAAATTGTGTCTGGTAAA
GTGCCGGATGACATGGTCAACAAGCGTTTGATGATGCTTGATATGGGCTCACTTGTCGCTGGCACCAAGTATCGTGGTGA
GTTTGAAGATCGGCTGAAGAAGATCATTGATGAAATTTATAAAGATGGCAATGTCATTTTGTTCATTGATGAATTGCATA
CTTTGATCGGTGCTGGCGGTGCAGAAGGCGCTATTGATGCTTCCAATATTTTGAAACCGGCATTAGCTCGTGGTGAATTA
CAATTGATCGGTGCCACGACCTTAGATGAATATCAAAAGTATATTGAAAAAGATGCTGCTTTGGAGCGGCGGTTTGCGAC
GATTCAAGTCGACGAACCAACTGAAGAAGAAGCTGAACAAATTTTGAAGGGCTTGCGTCCTCGTTATGAGGCGCATCACG
GTGTCACGATTACTGACGAAGCGCTGCATCAGGCGGTGGCTTTGTCATCACGGTACATCACGACTCGGTTCTTGCCTGAC
AAGGCAATTGATCTAGTTGACGAAAGTGCGGCGAAGGTTCGCTTGGACAAGGCCAATGTTGAGACGAAGGCCGACAAGCT
TCAGGATGAACTGGCCAAGCTGGTAGCTGATAAAGAAGACGCTATTGACCATCAAGATTTCGAAACGGCTGCGAACATCC
GGACTCAGGAAGCTGATTTAAAAACGAAGTTGGCCGACACGCCTGAACCAGTTAATGAAAGTGGCGTTCGAACTGACATT
AAAGTGACGGGCGACGATGTGGCAGAAGTGGTTTCTCAATGGACCGGTGTGCCAGTCACCCAGTTGCAGAAAAAAGAATC
CGATCGGTTGGTTAACTTGGAGAAGATCCTGCATGAGCGGGTTGTTGGCCAAGATGAAGCAGTTTCCGCCGTCGCGCGTG
CTATCCGGCGTGCTCGTTCTGGTTTGAAAGATCCGACGCGGCCAATTGGGTCCTTCATGTTTCTCGGGCCGACAGGTGTT
GGGAAAACGGAGCTGGCTAAGGCGTTAGCCGAGGCAATGTTTGGTTCTGAAGATGCCATGATCCGGGTTGATATGTCTGA
GTACATGGAGAAATTTAGTACCAGTCGGTTGATCGGCGCGGCCCCTGGTTACGTTGGTTACGACGAAGGCGGTCAACTAA
CCGAAAAAGTCCGCAATAAGCCTTACTCGGTTGTGTTGTTGGACGAAGTTGAAAAGGCGCATCCAGATGTCTTTAACATT
TTGCTGCAGGTGCTGGATGATGGCTATTTAACCGATTCGAAGGGTCGGCGGGTTGATTTCCGTAACACGATTTTGATCAT
GACCAGTAACATCGGCGCAACCGCTATTCGTGACGATAAGACTGTTGGCTTTGGTGCCAAGGATCCACAAGCTGACTTTA
ACGCCATGAAGAGCCGGATGCTGGACGAACTTAAAAAAGCGTTCCGACCAGAATTCCTTAACCGAATTGATGAAACCGTG
GTCTTCCACAGTCTCAACAAGGCTGAGCTGCATGAAATCGTTAAGATCATGACGAAGACAGTGCTTAGTCGCATTAAGGA
TCAAGGGATTGACGTTAAAATTACCCCAGCCGGTATTGACGCTGTCGCCGCTGCCGGCTTCGATCCAGAGTACGGTGCAC
GTCCAATTCGGCGGGCACTGCAAACCGGTGTCGAAGACCAGTTAAGTGAACTTTTACTGACAGGCCAAGCTAAAACCGGT
GATTTGATCCAAATTGGGGCTAAAAAAGGCAAGCTGACATTTACTGTTAAAGAGAACAAAGGCAAGCAAAAAGAAAACGG
TGCTTCAAAAGAACCCGTTAAAGCCTAG

Protein sequence :
MDNLFTPSAKNVLLLAQEQAKYFHHHAVGTEHLLMALVMEKDGIAGKTLRQLGVTENDVHDEIERFTGYGTVDAAGQASD
SYLPYSPKGKEILAFAGDEAKRLGALKIGTEHVLLGLLREDDILAARILQNLGLSLSKTRQMVFKKMGIADTAAKRRPMA
RGGARQDGQGTPTLDGLARDLTQMARENRMDPVVGRDKEVRRLIQILARRTKNNPVLIGEPGVGKTAIAEGFAEKIVSGK
VPDDMVNKRLMMLDMGSLVAGTKYRGEFEDRLKKIIDEIYKDGNVILFIDELHTLIGAGGAEGAIDASNILKPALARGEL
QLIGATTLDEYQKYIEKDAALERRFATIQVDEPTEEEAEQILKGLRPRYEAHHGVTITDEALHQAVALSSRYITTRFLPD
KAIDLVDESAAKVRLDKANVETKADKLQDELAKLVADKEDAIDHQDFETAANIRTQEADLKTKLADTPEPVNESGVRTDI
KVTGDDVAEVVSQWTGVPVTQLQKKESDRLVNLEKILHERVVGQDEAVSAVARAIRRARSGLKDPTRPIGSFMFLGPTGV
GKTELAKALAEAMFGSEDAMIRVDMSEYMEKFSTSRLIGAAPGYVGYDEGGQLTEKVRNKPYSVVLLDEVEKAHPDVFNI
LLQVLDDGYLTDSKGRRVDFRNTILIMTSNIGATAIRDDKTVGFGAKDPQADFNAMKSRMLDELKKAFRPEFLNRIDETV
VFHSLNKAELHEIVKIMTKTVLSRIKDQGIDVKITPAGIDAVAAAGFDPEYGARPIRRALQTGVEDQLSELLLTGQAKTG
DLIQIGAKKGKLTFTVKENKGKQKENGASKEPVKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LOCK919_2738 YP_008201233.1 ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence ClcC/MecB VFG0079 Protein 0.0 61
LOCK919_2738 YP_008201233.1 ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence ClcC/MecB VFG0080 Protein 1e-146 48