Gene Information

Name : fliI (I607_05070)
Accession : YP_008171076.1
Strain : Alteromonas macleodii Ionian Sea U4
Genome accession: NC_021710
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1122917 - 1124251 bp
Length : 1335 bp
Strand : +
Note : COG1157 Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
ATGACTAGCCCATGGCATGGTCACTTTGAATCACTGACTAAACAGGTCACAACGCCACCTGTAGTCGCAGCAGGGAAACT
CGTTCGCGGTATCGGCCTTACCCTTGAAGCCGTAGGTTGCCAGCTGCCGGTGGGTAGTCAATGTTTAGTGCAGACTGTGG
AAGGCGAGATAGAAGCAGAAGTGGTTGGCTTCGGTGATGATATAACCTATTTGATGCCGACAGAAGCGGTGCGAGGGATA
GTGCCCGGTAGTCGCGTTATGCCATTAAACCGTCAAAGTGGTTTGCCCGTTGGAATGGGGCTTTTAGGCCGCGTGGTAGA
CGGAAACGGACAGCCACTCGATGGACTTGGTGAAATTGATGCTGAAGCGAGAGCTCCCACCACGCGTCCTCCTATGAACC
CGCTTATTCGTCGTCCTATCAATGCGCCAATGGATGTGGGCGTGCGCGCTATTAACGCACTCAATACGGTAGGCGTAGGC
CAGCGTATGGGGCTGTTTGCCGGTAGTGGTGTGGGTAAAAGCGTACTGCTTGGCATGATGACCCGCGGTTGCGAAGCCGA
TGTGGTGGTGGTCGGGCTCGTCGGTGAACGTGGCCGGGAAGTGAAAGAATTTATACACGACATACTCACCGAAGAAGAGC
GTCAGCGCGCCGTTGTTGTCGCTGCCCCTGCAGACACCTCCCCGTTGATGCGCCTTAAAGGCTGCGAAACAGCGGTTACC
ATTGCTGAATATTTTCGTGACAAAGGGATGAAAGTTCTTCTTCTGATAGATTCCCTTACGCGCTACGCCATGGCGCAGCG
TGAAATTGCCCTTGCCGTTGGCGAGCCGCCTGCTACTAAAGGCTACCCACCGTCGGTGTTTGCTCGCCTACCTGCATTAG
TAGAGCGTGCCGGTAACGGCAGCGAGCGACAGGGTTCGATAACGGCTTTTTATACCGTATTAACCGAAGGTGATGATTTG
CAAGACCCCATTGCTGATGCGGCGCGCGCCATTTTGGATGGCCACGTTGTACTATCGCGCACTTTAGCCGATAGCGGTCA
TTACCCGGCTATAGATATCGAAGCGTCAATAAGTCGCGTTATGCCAATGGTGGTGAGTGAAGAGCACCAGCTTATGGCAC
GTCGCATTCGCCAGGTTTACTCAAATTACAAACAAAACCAAGACCTCATTTCTATTGGTGCTTATGCCAAGGGCTCAGAC
CCACGTATAGACTTAGCGATTCGTGCAGAGCCAGCGATTAATGCATTATTGCAACAAGGTATGAAGCAAGTCATTCCTTA
TGACGAAAGCTTAGAAGGCATGGCAGCCCTGGCTAAAGGGCTAGGGCAGGGGTGA

Protein sequence :
MTSPWHGHFESLTKQVTTPPVVAAGKLVRGIGLTLEAVGCQLPVGSQCLVQTVEGEIEAEVVGFGDDITYLMPTEAVRGI
VPGSRVMPLNRQSGLPVGMGLLGRVVDGNGQPLDGLGEIDAEARAPTTRPPMNPLIRRPINAPMDVGVRAINALNTVGVG
QRMGLFAGSGVGKSVLLGMMTRGCEADVVVVGLVGERGREVKEFIHDILTEEERQRAVVVAAPADTSPLMRLKGCETAVT
IAEYFRDKGMKVLLLIDSLTRYAMAQREIALAVGEPPATKGYPPSVFARLPALVERAGNGSERQGSITAFYTVLTEGDDL
QDPIADAARAILDGHVVLSRTLADSGHYPAIDIEASISRVMPMVVSEEHQLMARRIRQVYSNYKQNQDLISIGAYAKGSD
PRIDLAIRAEPAINALLQQGMKQVIPYDESLEGMAALAKGLGQG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-77 52
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-73 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-73 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-73 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-73 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-73 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 6e-84 48
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 6e-84 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-83 48
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-84 48
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-83 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-79 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-79 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-83 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-83 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-64 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 7e-70 47
escN CAI43874.1 EscN protein Virulence LEE Protein 5e-70 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 7e-70 47
escN AAC31513.1 L0034 Virulence LEE Protein 4e-70 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 5e-70 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-70 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 5e-70 47
escN AAK26715.1 EscN Virulence LEE Protein 9e-70 47
escN AAL57542.1 EscN Virulence LEE Protein 9e-70 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-70 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-69 47
escN AAC38383.1 EscN Virulence LEE Protein 5e-70 47
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-69 47
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-69 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 3e-69 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 4e-67 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-65 45
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-71 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 3e-66 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-67 44
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-63 44
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-63 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 3e-64 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-70 43
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-54 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 3e-54 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-54 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 3e-54 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 6e-65 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-65 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-65 42
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-53 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_008171076.1 flagellum-specific ATP synthase VFG2331 Protein 1e-105 62
fliI YP_008171076.1 flagellum-specific ATP synthase VFG1254 Protein 4e-112 61
fliI YP_008171076.1 flagellum-specific ATP synthase VFG2499 Protein 2e-113 59
fliI YP_008171076.1 flagellum-specific ATP synthase VFG0515 Protein 7e-74 50
fliI YP_008171076.1 flagellum-specific ATP synthase VFG0048 Protein 2e-80 48
fliI YP_008171076.1 flagellum-specific ATP synthase VFG0192 Protein 4e-76 47
fliI YP_008171076.1 flagellum-specific ATP synthase VFG0812 Protein 2e-70 47
fliI YP_008171076.1 flagellum-specific ATP synthase VFG0730 Protein 3e-70 47
fliI YP_008171076.1 flagellum-specific ATP synthase VFG0390 Protein 1e-75 46
fliI YP_008171076.1 flagellum-specific ATP synthase VFG2144 Protein 4e-79 45
fliI YP_008171076.1 flagellum-specific ATP synthase VFG0555 Protein 1e-54 43
fliI YP_008171076.1 flagellum-specific ATP synthase VFG2459 Protein 7e-60 42
fliI YP_008171076.1 flagellum-specific ATP synthase VFG1008 Protein 2e-56 41