Gene Information

Name : mecR1 (SABB_03471)
Accession : YP_008167231.1
Strain : Staphylococcus aureus Bmb9393
Genome accession: NC_021670
Putative virulence/resistance : Resistance
Product : methicillin resistance mecR1 protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 71069 - 72808 bp
Length : 1740 bp
Strand : +
Note : identified by sequence similarity; putative

DNA sequence : 
ATGTTAAGTATAATCAGTTCATTGCTCACGATATGTGTAATTTTTTTAGTGAGAATGCTCTATATAAAATATACTCAAAA
TATTATGTCACATAAGATTTGGTTATTAGTGCTCGTCTCCACGTTAATTCCATTAATACCATTTTACAAAATATCGAATT
TTACATTTTCAAAAGATATGATGAATCGAAATGTATCTGACACGACTTCTTCGGTTAGTCATATGTTAGATGGTCAACAA
TCATCTGTTACGAAAGACTTAGCAATTAATGTTAATCAGTTTGAGACCTCAAATATAACGTATATGATTCTTTTGATATG
GGTATTTGGTAGTTTGTTGTGCTTATTTTATATGATTAAGGCATTCCGACAAATTGATGTTATTAAAAGTTCGTCATTGG
AATCGTCATATCTTAATGAACGACTTAAAGTATGTCAAAGTAAGATGCAGTTCTACAAAAAGCATATAACAATTAGTTAT
AGTTCAAACATTGATAATCCGATGGTATTTGGTTTAGTGAAATCCCAAATTGTACTACCAACTGTCGTAGTCGAAACCAT
GAATGACAAAGAAATTGAATATATTATTCTACATGAACTATCACATGTGAAAAGTCATGACTTAATATTCAACCAGCTTT
ATGTTGTTTTTAAAATGATATTCTGGTTTAATCCTGCACTATATATAAGTAAAACAATGATGGACAATGACTGTGAAAAA
GTATGTGATAGAAACGTTTTAAAAATTTTGAATCGCCATGAACATATACGTTATGGTGAATCGATATTAAAATGCTCTAT
TTTAAAATCTCAGCACATAAATAATGTGGCAGCACAATATTTACTAGGTTTTAATTCAAATATTAAAGAACGTGTTAAGT
ATATTGCACTTTATGATTCAATGCCTAAACCTAATCGAAACAAGCGTATTGTTGCGTATATTGTATGTAGTATATCGCTT
TTAATACAAGCACCGTTACTATCTGCACATGTTCAACAAGACAAATATGAAACAAATGTATCATATAAAAAATTAAATCA
ACTAGCTCCGTATTTCAAAGGATTTGATGGAAGTTTTGTGCTTTATAATGAACGGGAGCAAGCTTATTCTATTTATAATG
AACCAGAAAGTAAACAACGATATTCACCTAATTCTACTTACAAAATTTATTTAGCGTTAATGGCATTCGACCAAAATTTA
CTCTCATTAAATCATACTGAACAACAATGGGATAAACATCAATATCCATTTAAAGAATGGAACCAAGATCAAAATTTAAA
TTCTTCAATGAAATATTCAGTAAATTGGTATTACGAAAATTTAAACAAACATTTAAGACAAGATGAGGTTAAATCTTATT
TAGATCTAATTGAATATGGTAATGAAGAAATATCAGGGAATGAAAATTATTGGAATGAATCTTCATTAAAAATTTCTGCA
ATAGAACAGGTTAATTTGTTGAAAAATATGAAACAACATAACATGCATTTTGATAATAAGGCTATTGAAAAAGTTGAAAA
TAGTATGACTTTGAAACAAAAAGATACTTATAAATATGTAGGTAAAACTGGAACAGGAATCGTGAATCACAAAGAAGCAA
ATGGATGGTTCGTAGGTTATGTTGAAACGAAAGATAATACGTATTATTTTGCTACACATTTAAAAGGCGAAGACAATGCG
AATGGCGAAAAAGCACAACAAATTTCTGAGCGTATTTTAAAAGAAATGGAGTTAATATAA

Protein sequence : 
MLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVLVSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQ
SSVTKDLAINVNQFETSNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKKHITISY
SSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQLYVVFKMIFWFNPALYISKTMMDNDCEK
VCDRNVLKILNRHEHIRYGESILKCSILKSQHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISL
LIQAPLLSAHVQQDKYETNVSYKKLNQLAPYFKGFDGSFVLYNEREQAYSIYNEPESKQRYSPNSTYKIYLALMAFDQNL
LSLNHTEQQWDKHQYPFKEWNQDQNLNSSMKYSVNWYYENLNKHLRQDEVKSYLDLIEYGNEEISGNENYWNESSLKISA
IEQVNLLKNMKQHNMHFDNKAIEKVENSMTLKQKDTYKYVGKTGTGIVNHKEANGWFVGYVETKDNTYYFATHLKGEDNA
NGEKAQQISERILKEMELI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mecR1 YP_039516.1 methicillin resistance protein MecR1 Not tested Type-II SCCmec Protein 0.0 100
mecR1 NP_370566.1 methicillin resistance protein Not tested Type-II SCCmec Protein 0.0 100
mecR1 NP_373279.1 methicillin resistance protein Not tested Type-II SCCmec Protein 0.0 100
mecR1 YP_190061.1 methicillin-resistance regulatory protein MecR1 Not tested Type-II SCCmec Protein 0.0 100
mecR1 BAA82219.2 sensor transducer protein MecR1 Not tested Type-II SCCmec Protein 0.0 100
mecR1 BAC57479.1 signaltransducer protein MecR1 Not tested Type-IIIinv SCCmec Protein 0.0 99
mecR1 YP_005754042.1 methicillin resistance protein MecR1 Not tested Type-XI SCCmec Protein 3e-134 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mecR1 YP_008167231.1 methicillin resistance mecR1 protein NC_002758.1120002.p0 Protein 0.0 100
mecR1 YP_008167231.1 methicillin resistance mecR1 protein NC_009782.5560215.p0 Protein 0.0 100
mecR1 YP_008167231.1 methicillin resistance mecR1 protein NC_002745.1122813.p0 Protein 0.0 100
mecR1 YP_008167231.1 methicillin resistance mecR1 protein NC_002952.2861159.p0 Protein 0.0 100
mecR1 YP_008167231.1 methicillin resistance mecR1 protein HE993884.1.gene10.p0 Protein 2e-125 48
mecR1 YP_008167231.1 methicillin resistance mecR1 protein FR823292.1.gene4.p01 Protein 2e-134 45