Gene Information

Name : ermA2 (SABB_05250)
Accession : YP_008168808.1
Strain : Staphylococcus aureus Bmb9393
Genome accession: NC_021670
Putative virulence/resistance : Resistance
Product : rRNA adenine N-6-methyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1838612 - 1839343 bp
Length : 732 bp
Strand : +
Note : identified by sequence similarity; putative

DNA sequence :
ATGAACCAGAAAAACCCTAAAGACACGCAAAATTTTATTACTTCTAAAAAGCATGTAAAAGAAATATTGAATCACACGAA
TATCAGTAAACAAGACAACGTAATAGAAATCGGATCAGGAAAAGGACATTTTACCAAAGAGCTAGTCAAAATGAGTCGAT
CAGTTACTGCTATAGAAATTGATGGAGGCTTATGTCAAGTGACTAAAGAAGCGGTAAACCCCTCTGAGAATATAAAAGTG
ATTCAAACGGATATTCTAAAATTTTCCTTCCCAAAACATATAAACTATAAGATATATGGTAATATTCCTTATAACATCAG
TACGGATATTGTCAAAAGAATTACCTTTGAAAGTCAGGCTAAATATAGCTATCTTATCGTTGAGAAGGGATTTGCGAAAA
GATTGCAAAATCTGCAACGAGCTTTGGGTTTACTATTAATGGTGGAGATGGATATAAAAATGCTCAAAAAAGTACCACCA
CTAAATTTTCATCCTAAGCCAAGTGTAGACTCTGTATTGATTGTTCTTGAACGACATCAACCATTGATTTCAAAGAAGGA
CTACAAAAAGTATCGATCTTTTGTTTATAAGTGGGTAAACCGTGAATATCGTGTTCTTTTCACTAAAAACCAATTCCGAC
AGGCTTTGAAGCATGCAAATGTCACTAATATTAATAAACTATCGAAGGAACAATTTCTTTCTATTTTCAATAGTTACAAA
TTGTTTCACTAA

Protein sequence :
MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHFTKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKV
IQTDILKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPP
LNFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYK
LFH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ermA NP_370576.1 rRNA methylase Not tested Type-II SCCmec Protein 5e-103 99
ermA NP_373288.1 rRNA methylase Not tested Type-II SCCmec Protein 5e-103 99
ermA-3 YP_190052.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 5e-103 99
unnamed BAB47663.1 rRNA adenine N-6-methyltransferase Not tested Type-III SCCmec Protein 8e-103 99
unnamed BAC53825.1 rRNA adenine N-6-methyltransferase Not tested SRImec-III and SCCmec-III region Protein 8e-103 99
ermA BAC57474.1 rRNA methylase Not tested Type-IIIinv SCCmec Protein 4e-103 99
ermA BAA82205.1 rRNA adenine N-6-methyltransferase Not tested Type-II SCCmec Protein 4e-103 99
ermA1 YP_039522.1 rRNA adenine N-6-methyltransferase 1 Not tested Type-II SCCmec Protein 5e-103 99
ermC NP_273130.1 rRNA adenine N-6-methyltransferase Not tested IHT-A Protein 6e-56 57

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_009782.5559229.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002758.1120012.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002952.2859614.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002745.1122822.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002745.1124324.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002745.1125313.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_009782.5559087.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002758.1121630.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002952.2859615.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002745.1123579.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_002745.1124852.p0 Protein 2e-103 99
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase AJ313523.1.orf0.gene Protein 5e-83 80
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase M64090.gene.p01 Protein 5e-60 62
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase M15332.gene.p01 Protein 5e-58 59
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase V01278.gene.p01 Protein 4e-57 58
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_010686.6295746.p0 Protein 3e-56 57
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_010685.6295744.p0 Protein 3e-56 57
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_007209.3523503.p0 Protein 3e-56 56
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase NC_007792.3912746.p0 Protein 1e-55 56
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase AM903082.gene3.p01 Protein 6e-48 52
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase AM410044.gene14.p01 Protein 6e-48 52
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase AM180355.1.gene2254. Protein 5e-47 51
ermA2 YP_008168808.1 rRNA adenine N-6-methyltransferase AM180355.1.gene2259. Protein 5e-47 51