Gene Information

Name : lysS (M621_20655)
Accession : YP_008160892.1
Strain : Serratia plymuthica S13
Genome accession: NC_021659
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 4354286 - 4355803 bp
Length : 1518 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTGAGCAACAACCACAGGGCGCCGATCAGGCGTTGGAACTCAATAACGAGTTGCAGTCACGCCGTGAGAAACTGGC
CGGGCTGCGCGAGAACGGCATTGCGTTCCCGAATGATTTCCGTCGCGACACCACGTCCGACAAGCTGCACGCTGCATACG
GCGATAAAGATAACGAAGAGCTGGAAGCGCTGGGCGTAGAAGTTACCGTTGCAGGCCGCATGATGACCCGTCGTATCATG
GGTAAAGCGTCATTCGTGACGTTGCAGGACGTCGGCGGCCGTATCCAGCTTTACGTCGCGCGCGACGATCTGGCGGAAGG
CGTTTATAACGAGCAGTTCAAGAAGTGGGATCTGGGCGATATCCTTGGCGCTCGCGGCAAGCTGTTCAAAACCAAGACCG
GCGAGCTGTCTATCCACTGTACCGAACTGCGTCTGCTGACCAAGGCTCTGCGCCCGTTGCCGGACAAGTTCCACGGCCTG
GCCGACCAGGAAACCCGCTACCGCCAGCGTTATCTGGACCTGATCGCCAACGATGAGTCGCGCAACACCTTCAAGGTGCG
CTCTCAGGTGATGGCGGGGATCCGTAACTTCATGGTGGAACGCGGCTTCATGGAAGTCGAAACCCCAATGATGCAGGTGA
TCCCTGGCGGCGCTTCTGCGCGTCCATTCGTGACTCACCACAATGCGCTGGACATCGATATGTACCTGCGTATTGCCCCG
GAGCTGTACCTGAAGCGTCTGGTGGTTGGGGGCTTCGAGCGGGTGTTCGAAATCAACCGTAACTTCCGTAACGAAGGCGT
TTCTCCGCGTCATAACCCAGAGTTCACCATGATGGAACTCTATATGGCTTACGCGGATTACAAAGACCTCATCGAGCTGA
CAGAGTCGCTGTTCCGCACCCTGACTCAGGACGTGCTGGGCAAAACTCAGGTGCAGTACGGTGACGAAGTGTTCGATTTC
GGCAAGCCGTTTGAAAAACTGACCATGACCGAGGCGATCAAAAAATACCGTCCTGAAACCGATCTGGCCGATCTGGCTGA
CATGGGCAAGGCGGTGGCTATCGCTGAATCCATCGGTATCAAGATTGAGAAGAGCTGGGGTCTGGGCCGTGTAGTCACCG
AGATCTTCGAAGAAGTGGCGGAAAGCCACCTGATTCAGCCGACCTTCATTACCGAATACCCGGCGGAAGTGTCCCCGCTG
GCGCGCCGTAATGATGAGAACCCAGAAATCACTGACCGTTTCGAGTTCTTCATTGGCGGGCGTGAAATCGGTAACGGCTT
CTCCGAGCTGAACGACGCGGAAGACCAGGCGCAGCGCTTTGCTGACCAAGTGAATGCGAAAGACGCAGGCGATGACGAAG
CAATGTTCTACGACGAAGACTACGTCACCGCGCTGGAGCACGGCCTGCCGCCGACGGCTGGCTTGGGTATCGGTATCGAT
CGCATGGTTATGCTGTTCACCAACAGCCACACCATCCGCGATGTGATTCTGTTCCCGGCAATGCGCCCGCAGAAATAA

Protein sequence :
MSEQQPQGADQALELNNELQSRREKLAGLRENGIAFPNDFRRDTTSDKLHAAYGDKDNEELEALGVEVTVAGRMMTRRIM
GKASFVTLQDVGGRIQLYVARDDLAEGVYNEQFKKWDLGDILGARGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
ADQETRYRQRYLDLIANDESRNTFKVRSQVMAGIRNFMVERGFMEVETPMMQVIPGGASARPFVTHHNALDIDMYLRIAP
ELYLKRLVVGGFERVFEINRNFRNEGVSPRHNPEFTMMELYMAYADYKDLIELTESLFRTLTQDVLGKTQVQYGDEVFDF
GKPFEKLTMTEAIKKYRPETDLADLADMGKAVAIAESIGIKIEKSWGLGRVVTEIFEEVAESHLIQPTFITEYPAEVSPL
ARRNDENPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFADQVNAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGID
RMVMLFTNSHTIRDVILFPAMRPQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-170 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_008160892.1 lysyl-tRNA synthetase VFG1668 Protein 3e-170 69