Gene Information

Name : guaA (M621_19120)
Accession : YP_008160594.1
Strain : Serratia plymuthica S13
Genome accession: NC_021659
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 4027486 - 4029063 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGACAAATAATATCCATAAGCATCGCATCCTTATTCTGGATTTTGGTTCGCAATACACTCAACTGGTAGCACGCCGCGT
GCGCGAAATCGGCGTTTACTGCGAGCTGTGGGCCTGGGACGTTAGCGAAGAGCAAATCCGCGAATTCAATCCAAGCGGCA
TCATCCTTTCCGGCGGCCCGGAGAGCACCACCGAACATAACAGCCCGCGTGCGCCAGAATACGTGTTCACCGCCGGTGTA
CCGGTACTGGGCGTATGCTACGGTATGCAGACCATGGCGATGCAGCTGGGCGGCCATGTGCAGGGTTCCAACGAGCGTGA
GTTCGGCTATGCGCAGGTGGAAGTGACCACCGACAGCGCGCTGGTGCGCGGCATCGAAGACGCCCTCAGCGTTGCCGGCA
AACCGCTGCTGGACGTGTGGATGAGCCACGGCGACAAAGTGACCGCCATCCCTTCCGACTTCGTGACCGTCGCCAGCACC
GATACCTGCCCGTTCGCCATTATGGCCAACGAAGAAAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CCGTCAGGGCCAGCGCATGCTGGAGCGTTTCGTGCTGGATATCTGCCAGTGTGAAGCCCTGTGGACGCCTGCGACCATCA
TCGAAGATGCGGTTGAGCGTATCCGCGAGCAAGTGGGCGAAGATCACGTGATCCTCGGCCTTTCCGGCGGCGTGGATTCT
TCCGTTACCGCCATGCTGCTGCACCGCGCCATCGGCAAACGCCTGACCTGCGTGTTTGTGGACAACGGCCTGCTGCGCCT
GAACGAAGCCGACCAGGTGCTGGAGATGTTCGGCGACCACTTCGGCCTGAACATCGTGCACGTCGCGGCGGAAAACCGCT
TCTTGGACGCACTGGCCGGCGTTGACGAGCCGGAAGCCAAGCGCAAGATCATCGGCCGCGTATTCGTTGAAGTGTTCGAC
GAAGAAGCCTGCAAGCAAGACGAAGTGAAATGGCTGGCGCAAGGCACCATCTACCCGGACGTGATCGAGTCCGCCGCTTC
CGCCACCGGCAAAGCGCACGTGATCAAGTCGCACCACAACGTGGGTGGCCTGCCGAAAGAGATGAAGCTGGGCCTGGTAG
AGCCGCTGAAAGAGCTGTTCAAAGACGAAGTGCGCAAAATCGGCCTGGAGCTGGGCCTGCCGTACGACATGCTGTACCGC
CACCCGTTCCCGGGGCCAGGTCTGGGCGTGCGCGTGCTGGGCGAAGTGAAGAAAGAGTACTGTGATCTGCTGCGCCGTGC
CGACGCCATCTTCATCGAAGAGCTGCATAAAGCCGATCTGTACAACAAGGTCAGCCAGGCATTCACCGTATTCCTGCCGG
TGCGTTCGGTCGGCGTGATGGGCGACGGCCGTAAATACGACTGGGTTGTTTCACTGCGCGCAGTGGAAACCATCGACTTT
ATGACCGCGCATTGGGCGCACCTGCCGTACGACTTCCTCGGCCGCGTCTCCAACCGCATCATCAACGAAGTGGACGGCAT
TTCCCGCGTAGTTTATGACATCAGCGGCAAGCCACCGGCTACCATTGAGTGGGAGTGA

Protein sequence :
MTNNIHKHRILILDFGSQYTQLVARRVREIGVYCELWAWDVSEEQIREFNPSGIILSGGPESTTEHNSPRAPEYVFTAGV
PVLGVCYGMQTMAMQLGGHVQGSNEREFGYAQVEVTTDSALVRGIEDALSVAGKPLLDVWMSHGDKVTAIPSDFVTVAST
DTCPFAIMANEEKRFYGVQFHPEVTHTRQGQRMLERFVLDICQCEALWTPATIIEDAVERIREQVGEDHVILGLSGGVDS
SVTAMLLHRAIGKRLTCVFVDNGLLRLNEADQVLEMFGDHFGLNIVHVAAENRFLDALAGVDEPEAKRKIIGRVFVEVFD
EEACKQDEVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVDGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-127 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-127 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-127 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-111 48