Gene Information

Name : tpx (M621_13480)
Accession : YP_008159493.1
Strain : Serratia plymuthica S13
Genome accession: NC_021659
Putative virulence/resistance : Virulence
Product : lipid hydroperoxide peroxidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2826903 - 2827406 bp
Length : 504 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; Derived by automated computational analysis using gene prediction method: Protein Homolog

DNA sequence :
ATGACTCAGACAGTACATTTCCAAGGCAACCCGGTCAGCGTTGCAGGCCATCTGCCACAGTCAGGCGAACAAGCCAAAGC
GTTCTCGCTGGTTGCCAAAGACCTGTCAGACGTAGCGCTAAGCAGCTTCGCGGGTAAACGCAAAGTCCTGAACATTTTCC
CAAGTATTGATACCGGCGTTTGCGCTGCCTCGGTACGTAAATTCAACCAACTGGCCAGCGGTCTGGATAATACCGTGGTG
CTGTGCATCTCCTCCGATTTGCCGTTCGCCCAGTCACGCTTCTGCGGCGCGGAAGGTCTGAGCAACGTAGTGACGCTGTC
TACCCTGCGTGGTTCAGAATTCAAACAGGCTTACGGCGTCGAAATCGCAGAAGGCCCGTTGGCGGGTCTGACTGCGCGTG
CGGTCGTGGTGCTGGATGGCCAGGACAATGTGCTGTACAGCGAGCTGGTGAATGAGATCACCAACGAGCCGGATTACGAT
GCTGCGCTGGCTGCACTGAAGTGA

Protein sequence :
MTQTVHFQGNPVSVAGHLPQSGEQAKAFSLVAKDLSDVALSSFAGKRKVLNIFPSIDTGVCAASVRKFNQLASGLDNTVV
LCISSDLPFAQSRFCGAEGLSNVVTLSTLRGSEFKQAYGVEIAEGPLAGLTARAVVVLDGQDNVLYSELVNEITNEPDYD
AALAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 8e-35 49
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-34 49
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 5e-35 49
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-34 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_008159493.1 lipid hydroperoxide peroxidase VFG0087 Protein 2e-35 49