Gene Information

Name : sirA (M621_09275)
Accession : YP_008158671.1
Strain : Serratia plymuthica S13
Genome accession: NC_021659
Putative virulence/resistance : Virulence
Product : response regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1945710 - 1946366 bp
Length : 657 bp
Strand : +
Note : in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate v

DNA sequence : 
TTGATTAGCGTTCTTCTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTTGAAGATATCAAAGGTAT
AAAAGTTGTCGGGGAGGCCCAGTGCGGTGAAGACGCCGTGAAATGGTGCCGTGGCAATGCTGTAGATATCGTTCTTATGG
ATATGAATATGCCGGGCATTGGCGGGCTGGAAGCTACGCGCAAGATTGTACGTTATGCGCCCGACGTTAAAGTCATCATG
TTGACTATTCATACTGAAAACCCATTGCCTGCCAAGGTGATGCAGGCAGGTGCTGCAGGCTACCTGAGTAAGGGGGCTGC
GCCGCAGGATGTGGTTAACGCTATCCGGTCGGTGCAGGCAGGCCAGCGCTACATCGCATCGGACATTGCCCAGCAGATGG
CATTGAGCCAACTGGAGCCGCAGACGGAAACCCCGTTCAGTTGCCTGTCTGAACGTGAACTGCAGATTATGCTGATGATC
ACCAAAGGCAAAAAGGTGAATGAGATCTCGGAACAACTGAACCTCAGTCCTAAAACGGTGAACAGCTACCGTTATCGTAT
GTTCAGTAAACTGAATATCAGCGGTGACGTCGAATTGACACACCTGGCTATCCGACACGGATTGTTCAATGCGGAGACGT
TGTTAAGCAGTGAGTGA

Protein sequence : 
MISVLLVDDHELVRAGIRRILEDIKGIKVVGEAQCGEDAVKWCRGNAVDIVLMDMNMPGIGGLEATRKIVRYAPDVKVIM
LTIHTENPLPAKVMQAGAAGYLSKGAAPQDVVNAIRSVQAGQRYIASDIAQQMALSQLEPQTETPFSCLSERELQIMLMI
TKGKKVNEISEQLNLSPKTVNSYRYRMFSKLNISGDVELTHLAIRHGLFNAETLLSSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00302 YP_008207767.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR25 Protein 1e-48 49
BJAB0868_00306 YP_008211632.1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Not tested AbaR26 Protein 1e-48 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sirA YP_008158671.1 response regulator VFG1889 Protein 2e-55 49