Gene Information

Name : M621_08795 (M621_08795)
Accession : YP_008158577.1
Strain : Serratia plymuthica S13
Genome accession: NC_021659
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 1848939 - 1849688 bp
Length : 750 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; Derived by automated computational analysis using gene prediction method:

DNA sequence :
ATGAGTTTTATCGCTATTATTCCAGCCCGTTACGCATCAACCCGTTTGCCGGGCAAGCCGTTGGCCGATATTCACGGTAA
GCCAATGGTGGTGCACGTAATGGAACGTGCACGTGAGTCCGGCGCCAGCCGCGTTATCGTAGCGACCGATCACCCCGAAG
TGGCCAAAGCGGTCAAAGCCGCCGGTGGCGAAGTGTGCATGACCAGCCCGCATCACCATTCCGGTACCGAACGCCTGGCG
GAAGTGATCGAGCATTATGGTTTTGCCGATGACGAAATCATCGTTAACGTGCAGGGTGACGAACCGATGATCCCGCCGGT
GATCGTACGCCAGGTGGCAGAAAACCTGGCAGCCAGCCAGGCCGGCATGGCCACTCTCGCGGTACCGATCGCCAGCGCGG
AAGAAGCCTTTAACCCTAATGCCGTCAAAGTAGTGATGGATGCACAGGGTTATGCGCTCTATTTTTCACGCGCGACTATT
CCCTGGGATCGGGAACGTTTTGCTCAATCCAAAGAAAGTATCGGCGACAGCCTGCTGCGCCACATCGGCATTTACGCCTA
TCGTGCCGGTTTTGTGCGCCGTTATGTCAGCTGGGCGCCAAGCCAACTGGAGCAAATTGAGCTGCTGGAGCAACTGCGGG
TGCTGTGGTACGGTGAAAAAATCCATGTGGGGGTTGCTAAAGCCATTCCAACCGTGGGTGTTGATACGCCGGAAGATCTG
CAGCGCGTGCGCGACAGCATCAAGGGCTAA

Protein sequence :
MSFIAIIPARYASTRLPGKPLADIHGKPMVVHVMERARESGASRVIVATDHPEVAKAVKAAGGEVCMTSPHHHSGTERLA
EVIEHYGFADDEIIVNVQGDEPMIPPVIVRQVAENLAASQAGMATLAVPIASAEEAFNPNAVKVVMDAQGYALYFSRATI
PWDRERFAQSKESIGDSLLRHIGIYAYRAGFVRRYVSWAPSQLEQIELLEQLRVLWYGEKIHVGVAKAIPTVGVDTPEDL
QRVRDSIKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-27 46
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-27 46
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-28 46