Gene Information

Name : entE (SCE1572_23325)
Accession : YP_008151070.1
Strain : Sorangium cellulosum So0157-2
Genome accession: NC_021658
Putative virulence/resistance : Virulence
Product : enterobactin synthase subunit E
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 6579900 - 6581486 bp
Length : 1587 bp
Strand : +
Note : bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate;

DNA sequence : 
GTGGCCGAGCTCTACCGGCGCGAAGGCTACTGGCGCGGCGAGACGTTCGGGGACCTGCTCCGCGAGCGGGCCGCGCAGCA
CCCGCACCGGATCGCCCTCGTCGGCGACGATCGCCGGCTGAGCTACGGCGAGCTCGATCGGCGCGCCGACCGCCTCGCCG
CGGGCCTCCTGCGCCTCGGGATCCAGCCGCGGGATCGCGTGGTGGTCCAGCTCCCGAACATCGTGGAGTTCTTCGAGGTG
TGCTTTGCGTTGTTCCGCCTCGGCGCCCTCCCCGTCCTCGCCCTGCCCGCCCACCGGCGCGCCGAGATCACGTATTTCTG
CGAGCACACGGGGGCGGTCGCCTACGTCGTCGCCGACCGGGACGGCGGGTTCGACTACCGGGAGCTGGCGAGTCAGGTCC
GGCGGGACGTGAAGACCTTGAAGCACGTCCTCGTGGCCGGCCAGCCCGGCGAGCACACCGCGCTCGAGGGCGTGCACGCC
GATCCCGTGGAGCTGCCGAGCCCCGCGGCGGGCGACGTGGCCTTCTTCCAGCTGTCCGGCGGGAGCACCGGAGTGCCCAA
GCTGATCCCGCGGACGCACGACGATTATCTCTACAGCGTGCGTGCCAGCGCGGAGATCTGCGCCCTCGACGCGGGCAGCG
TGTACCTGGCCGTCCTGCCCGTCGCGCACAACTTCACCCTGAGCTCGCCGGGGAGCCTCGGCGCGCTCTGCGCCGGCGGC
CGCGTGGTGCTCAGCCGCCGTCCCAGCCCGGACGAGGCGTTCCCCTGGATCGAGCGGGAGAAGGTCACGATCACCGCGCT
CGTGCCGCCGCTCGCCGCGCTGTGGCTGGAGTCGGCCCGGACGGCGCGGCACGACCTGTCGAGCTTGAAGGTGCTCCAGG
TGGGCGGCGCCAAGCTCGCCGCGGAGGTGGCGCGCCGGGTGCGGCCGACGCTGGGCTGCGCCCTGCAACAGGTGTTCGGG
ATGGCCGAGGGGCTGGTCAACTATACCCGCCTCGACGATCCCGAGGAGATCACGACTGAGACCCAGGGCCGGCCCATCTC
GCCCCACGACGAGGTCCGCGTCGTGGACGACGAGGACCGCGACGTCGACGACGGGCTGGTCGGTCACCTGCTCACGCGCG
GGCCTTACACCATCCGCGGCTATTACAAGGCCGACGCGCACAACGCGAAGGCGTTCACGCGCGACGGCTTCTACCGCACG
GGCGATCTCGTGCGGCGCACGCCGTCGGGCTACCTGGTCGTCGAGGGCCGCGCAAAGGACCAGATCAACCGCGGCGGCGA
GAAGATCGCGGCCGAGGAGGTCGAGAACCACGTCCTCGCCCACCCGGCGGTGCGCGACGCGGCGCTCGTGGCCATGCCGG
ACGAGCGGCTCGGCGAGCGGTCGTGCGCGTTCCTCGTGCCCCGCGGGCAGCCGCCGGCCGCGCGCGAGATCAACGCCTTC
CTGCGCGAGCGCGGGGTCGCTCTGTACAAGGTGCCCGATCGCATCGAGTGGCTCGAGGCGCTCCCGACGACGAGCGTCGG
CAAGGTGGACAAGAAGGCGCTCCGCAAGTGGATCGCCGATCGGCTCGCGCAGGGCGCCGAGCGCTGA

Protein sequence : 
MAELYRREGYWRGETFGDLLRERAAQHPHRIALVGDDRRLSYGELDRRADRLAAGLLRLGIQPRDRVVVQLPNIVEFFEV
CFALFRLGALPVLALPAHRRAEITYFCEHTGAVAYVVADRDGGFDYRELASQVRRDVKTLKHVLVAGQPGEHTALEGVHA
DPVELPSPAAGDVAFFQLSGGSTGVPKLIPRTHDDYLYSVRASAEICALDAGSVYLAVLPVAHNFTLSSPGSLGALCAGG
RVVLSRRPSPDEAFPWIEREKVTITALVPPLAALWLESARTARHDLSSLKVLQVGGAKLAAEVARRVRPTLGCALQQVFG
MAEGLVNYTRLDDPEEITTETQGRPISPHDEVRVVDDEDRDVDDGLVGHLLTRGPYTIRGYYKADAHNAKAFTRDGFYRT
GDLVRRTPSGYLVVEGRAKDQINRGGEKIAAEEVENHVLAHPAVRDAALVAMPDERLGERSCAFLVPRGQPPAAREINAF
LRERGVALYKVPDRIEWLEALPTTSVGKVDKKALRKWIADRLAQGAER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-99 50
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-99 50
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-100 50
ybtE CAA21394.1 - Virulence HPI Protein 7e-100 50
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 5e-100 50
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 8e-100 50
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-100 50
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 7e-100 50
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-100 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
entE YP_008151070.1 enterobactin synthase subunit E VFG0168 Protein 6e-126 57
entE YP_008151070.1 enterobactin synthase subunit E VFG0932 Protein 2e-110 50
entE YP_008151070.1 enterobactin synthase subunit E VFG1817 Protein 1e-102 50