Gene Information

Name : guaA (SCE1572_22185)
Accession : YP_008150845.1
Strain : Sorangium cellulosum So0157-2
Genome accession: NC_021658
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 6274043 - 6275617 bp
Length : 1575 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGCTAGCGGCAGCCATGCTCTCACCCCGTCGGGACTTCGTCGTCATCCTCGATTTCGGCTCTCAGTACACGCAGCTCAT
CGCCCGGCGTGTGCGCGAGTCGGGCGTCTACTGCGAGATCCACCGCTTCGACGTGCCGATCGCCGAGCTGCGCCGGCTCG
CCCCGCGCGCGCTCATCCTCTCCGGCGGCCCCGCCAGCGTGTACGGAGACAACGCGCCGCACTGCTCCCGCGAGGTGCTG
GAGCTCGGCGTCCCGACGCTGGGCATCTGCTACGGCCTCCAGCTCATGGCGCACCACCTCGGCGGCAAGGTCGAGCGCGC
GCACACGGGGGGCGAGTACGGCCCCGCCACGGTGCGGATCGATCGCCCGACCGGCATCTTCTCCCGCTTCGTCGAGGGCG
ACTCCATCGACGTCTGGATGAGCCACGGCGATCGCCTCGCGGCGATGCCGGAGGGGTTCGTCGCGCTCGGCACCACGCCC
GGCAGCCCGCTCTGCGCCGTCGCCCGCGAGCGCGACAAGCTCTACGGCCTCCAGTTCCACCCCGAGGTCGTCCACACCCC
GCGCGGCAAGGAGATCCTCCAGGCGTTCCTCTTCGACGTCGCCGGCCTCTCCCCGACGTGGACGCCCGCGTCGTTCGTGG
AGGAGGCGATCGCGGCGGTCCGCGAGAAGGCCGGCCCGCACGACCGCGTCATCCTGGGCCTCTCCGGCGGCGTCGACTCC
TCGGTCGCCGCGGTCCTCTGCCAGCGCGCCCTCGGCGACCGGCTGACGTGCATCTTCGTCGACAACGGCCTCCTGCGCGA
GGGCGAGGCCGAGGCCGTCGAGCGGACGTTCCGCGGCCACTTCCACATGAACCTCGACGCCGTCGACGCGTCGGCGCGCT
TCCTCGAGGGGCTGCGCGGCGTCGTGGATCCCGAGCAGAAGCGCAAGGTGATCGGCCGGCTCTTCATCGAGGTGTTCGAG
GAGGAGGCGAAGCGCGTCGAGGGCGCGAAGTGGCTCGTCCAGGGCACGCTCTACCCCGACGTGATCGAGAGCGTCTCGTT
CAAGGGGCCGAGCGCCGTCATCAAGAGCCACCACAACGTCGGCGGCCTGCCCGAGCGGATGAACCTCGGCCTCATCGAGC
CGCTGCGGGAGCTCTTCAAGGACGAGGTGCGCGCCGCCGGCGAGGCGCTCGGCATGCCGCGGGAGATCCTCTACCGCCAG
CCGTTCCCCGGCCCGGGGCTCGCGGTGCGGTGCCTCGGCGAGGTGACGCCGGAGAAGCTCCGCGTGCTCAGGGCGGCCGA
CACGATCTTCGACCAGGAGATCCGCGCCGCCGGGCTCTACGAGTCGCTCTGGCAGAGCTTCTGCGTGCTCCTCCCGGTCC
GCTCGGTGGGCGTGATGGGCGACGAGCGCACCTACGACGAGGCGATCGCGCTCCGCGCGGTGCACTCGACCGACGGCATG
ACCGCCGACTGGGCGCGGCTGCCCTACGACCTCATCGCGCGGGTGAGCTCGCGCATCATCAACGAGGTGCGCGGCGTGAA
CCGCGTGGTGCTCGACGTGTCGTCGAAGCCCCCCTCGACCATCGAGTGGGAGTGA

Protein sequence :
MLAAAMLSPRRDFVVILDFGSQYTQLIARRVRESGVYCEIHRFDVPIAELRRLAPRALILSGGPASVYGDNAPHCSREVL
ELGVPTLGICYGLQLMAHHLGGKVERAHTGGEYGPATVRIDRPTGIFSRFVEGDSIDVWMSHGDRLAAMPEGFVALGTTP
GSPLCAVARERDKLYGLQFHPEVVHTPRGKEILQAFLFDVAGLSPTWTPASFVEEAIAAVREKAGPHDRVILGLSGGVDS
SVAAVLCQRALGDRLTCIFVDNGLLREGEAEAVERTFRGHFHMNLDAVDASARFLEGLRGVVDPEQKRKVIGRLFIEVFE
EEAKRVEGAKWLVQGTLYPDVIESVSFKGPSAVIKSHHNVGGLPERMNLGLIEPLRELFKDEVRAAGEALGMPREILYRQ
PFPGPGLAVRCLGEVTPEKLRVLRAADTIFDQEIRAAGLYESLWQSFCVLLPVRSVGVMGDERTYDEAIALRAVHSTDGM
TADWARLPYDLIARVSSRIINEVRGVNRVVLDVSSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-127 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-128 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-128 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-128 50