Gene Information

Name : M062_26220 (M062_26220)
Accession : YP_008135622.1
Strain : Pseudomonas aeruginosa RP73
Genome accession: NC_021577
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5652565 - 5654448 bp
Length : 1884 bp
Strand : -
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Hom

DNA sequence :
ATGAGCGCAACGCAGAAGAACAACATCACCCGCCTTGAGCAGCTCGACCGCCAGTCGACGCAGCCTTTCCCGAACTCGCG
CAAGGTCTACCTGACCGGCTCGCGCCCGGACATCCGCGTCCCGGTGCGGGAAATCTCCCTCGCCGACACCCCCACCGCCT
TCGGCGGCGAAAAGAACCCGCCGGTGTTCGTCTACGACACCTCCGGCCCGTATACCGACCCTGAGGTCCGCATCGACCTG
CGCAAGGGCCTGCCTGACGTGCGTTCGCGCTGGATCGACGAGCGCGGCGACACCGAGATCCTCCCCGGCCTGACCTCCGA
GTTCGGCCAGGCCCGCCTGGCCGACGCCAGCCTCGACGCCCTGCGCTTCGCCCACGTGCGCACGCCGCGCCGGGCCAAGC
CGGGCGCCAACGTCTCGCAGATGCACTACGCGAAGAAAGGCATCATCACCCCGGAGATGGAATACATCGCCATCCGCGAG
AACATGAAGCTGCAGGAAGCCCGGGCCGCCGGCCTGCTCGACCAGCAGCACCCGGGGCACAGCTTCGGCGCCAACATCCC
GAAGGAAATCACCCCCGAGTTCGTCCGCGAGGAAGTCGCCCGCGGCCGCGCGATCATTCCGGCGAACATCAACCACACCG
AGCTTGAGCCGATGATCATCGGCCGCAACTTCCTGGTGAAGATCAACGGCAACATCGGCAACAGCGCGCTGGGCTCCTCG
ATCGAGGAAGAGGTGGAGAAGCTCACCTGGGGCATCCGCTGGGGCGCCGACACGGTGATGGACCTGTCCACCGGCAAGCA
CATCCATGAAACCCGCGAGTGGATCCTGCGCAACAGCCCGGTACCGATCGGCACCGTACCGATCTACCAGGCGCTGGAGA
AGGTCAACGGCGTCGCCGAGGACCTGACCTGGGAAATCTTCCGCGACACCCTGATCGAACAGGCCGAGCAGGGCGTCGAC
TACTTCACCATCCACGCCGGCGTGCTGCTGCGCTATGTGCCGCTGACCGCCAAGCGGGTCACCGGCATCGTTTCCCGCGG
CGGCTCGATCATGGCCAAGTGGTGCCTGGCGCACCACCAGGAGAACTTCCTCTACACGCATTTCGAAGAGATCTGCGAAA
TCATGAAGGCCTACGACGTCAGCTTCTCGCTGGGCGATGGCCTGCGTCCGGGCTCGGTGGCCGACGCCAACGACGCCGCC
CAGTTCGGCGAGCTGGAAACCCTCGGCGAGCTGACCAAGATCGCCTGGAAGCACGACGTGCAGGTGATGATCGAAGGTCC
CGGCCACGTGCCGATGCAATTGATCAAGGAAAACATGGACAAGCAGCTGGAGTGCTGTGACGAGGCGCCGTTCTACACCC
TCGGCCCGCTGACCACCGACATCGCCCCCGGCTACGACCACATCACCTCCGGCATCGGCGCGGCGATGATCGGCTGGTTC
GGCTGCGCCATGCTCTGCTACGTCACGCCCAAGGAGCACCTGGGTCTGCCGAACAAGGATGATGTGAAGACCGGGATCAT
CACCTACAAGATCGCCGCCCATGCCGCCGACCTCGCCAAGGGCCACCCGGGCGCGCAGATCCGCGACAACGCGCTATCCA
AGGCGCGCTTCGAGTTCCGTTGGGAGGACCAGTTCAACCTTGGCCTGGACCCGGACACCGCGCGGGCGTTCCATGACGAG
ACCCTGCCGAAGGACTCGGCCAAGGTCGCGCACTTCTGCTCCATGTGCGGACCGAAGTTCTGCTCGATGAAGATCACCCA
GGAAGTCCGCGACTACGCCAAGGAGAACGGCCTGTCCGACGAGAGCAAGGCCATCGAGGCTGGCTTCCAGGAGCAGGCGG
CGCGCTTCAAGGACGAAGGATCGGTGATCTACAGGCAGGTGTAG

Protein sequence :
MSATQKNNITRLEQLDRQSTQPFPNSRKVYLTGSRPDIRVPVREISLADTPTAFGGEKNPPVFVYDTSGPYTDPEVRIDL
RKGLPDVRSRWIDERGDTEILPGLTSEFGQARLADASLDALRFAHVRTPRRAKPGANVSQMHYAKKGIITPEMEYIAIRE
NMKLQEARAAGLLDQQHPGHSFGANIPKEITPEFVREEVARGRAIIPANINHTELEPMIIGRNFLVKINGNIGNSALGSS
IEEEVEKLTWGIRWGADTVMDLSTGKHIHETREWILRNSPVPIGTVPIYQALEKVNGVAEDLTWEIFRDTLIEQAEQGVD
YFTIHAGVLLRYVPLTAKRVTGIVSRGGSIMAKWCLAHHQENFLYTHFEEICEIMKAYDVSFSLGDGLRPGSVADANDAA
QFGELETLGELTKIAWKHDVQVMIEGPGHVPMQLIKENMDKQLECCDEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWF
GCAMLCYVTPKEHLGLPNKDDVKTGIITYKIAAHAADLAKGHPGAQIRDNALSKARFEFRWEDQFNLGLDPDTARAFHDE
TLPKDSAKVAHFCSMCGPKFCSMKITQEVRDYAKENGLSDESKAIEAGFQEQAARFKDEGSVIYRQV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 78
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 78
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 74