Gene Information

Name : ureB (M062_25685)
Accession : YP_008135517.1
Strain : Pseudomonas aeruginosa RP73
Genome accession: NC_021577
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 5535255 - 5535560 bp
Length : 306 bp
Strand : +
Note : ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzym

DNA sequence :
ATGATCCCCGGTGAATACGACATCCAGCCCGGCGATATCGAACTCAACGCCGGCCGCCGCACCCTCGCCCTGAGCGTGGC
GAACACCGGCGACCGGCCGATCCAGGTCGGCTCGCACTACCACTTCTTCGAGGTCAACGACGCCCTCGCCTTCGACCGTC
CGGCCACCCGTGGCATGCGCCTGAACATCGCCGCCGGCACCGCGGTGCGCTTCGAACCGGGGCAGAGCCGCGAGGTGGAG
CTGGTGGAAATCGGCGGCGGACGGCGGGTATACGGCTTTGCCGGGCGGGTGATGGGGGACCTCTAG

Protein sequence :
MIPGEYDIQPGDIELNAGRRTLALSVANTGDRPIQVGSHYHFFEVNDALAFDRPATRGMRLNIAAGTAVRFEPGQSREVE
LVEIGGGRRVYGFAGRVMGDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureB NP_286679.1 urease subunit beta Virulence TAI Protein 5e-28 71
ureB NP_287087.1 urease subunit beta Not tested TAI Protein 5e-28 71
ureB YP_003784326.1 urease subunit beta Not tested PiCp 7 Protein 5e-24 57
ureB YP_005682175.1 Urease beta subunit Not tested PiCp 7 Protein 3e-24 57
ureB YP_005684267.1 Urease beta subunit Not tested PiCp 7 Protein 3e-24 57
ureB YP_005686359.1 Urease beta subunit Not tested PiCp 7 Protein 3e-24 57