Gene Information

Name : M062_21745 (M062_21745)
Accession : YP_008134756.1
Strain : Pseudomonas aeruginosa RP73
Genome accession: NC_021577
Putative virulence/resistance : Virulence
Product : betaine-aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : 1.2.1.8
Position : 4676521 - 4677981 bp
Length : 1461 bp
Strand : +
Note : catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGATCAAACACTGGATCAATGGCCGCGAGGTCGAAAGCAAGGACGTCTTCGAGAACTACAACCCGGCCACCGGCGAGCT
GATCGGCGAGGTTGCCAGCGGCGGCGCGGCGGAAATCGACGCGGCGGTGGCGGCGGCCCGGGAAGCCTTCCCGAAATGGG
CCAATACCCCGGCCAAGGAGCGCGCGCGCCTGATGCGCCGGCTCGGCGAGCTGATCGACCGGAACGTGCCGCACCTGGCG
GAACTGGAGACCCTCGACACCGGCCTGCCGATCCACCAGACGAAGAACGTGCTGATCCCGCGCGCCTCGCACAACTTCGA
GTTCTTCGCCGAAGTCTGCACGCGGATGAACGGGCACAGCTATCCGGTCGACGACCAGATGCTCAACTACACCCTGTACC
AGCCGGTCGGCGTCTGCGGCCTGGTCTCGCCGTGGAACGTACCGTTCATGACCGCCACCTGGAAGACCGCGCCGTGCCTG
GCGCTGGGCAACACGGCGGTGCTGAAGATGTCCGAGCTGTCGCCGCTGACCGCCAACGAGCTGGGCCGCCTGGTGCACGA
GGCGGGCATTCCGCCGGGGGTGTTCAACGTGGTCCAGGGCTACGGCGCCAGCGCCGGCGACGCGCTGGTTCGCCACCGCG
ACGTGCGCGCGGTGTCCTTCACCGGCGGCACCGCCACCGGGCGACGGATCATGGAGGCGGCCGGGATCAAGAAATACTCG
ATGGAACTGGGCGGCAAGTCGCCGGTGCTGGTCTTCGAAGACGCCGACCTCGAGCGGGCGCTGGACGCCGCTCTGTTCAC
CATCTTCTCGCTGAACGGCGAGCGCTGCACCGCCGGCAGTCGCATCTTCGTCCAGGAAAGCGTCTACCCGCAGTTCGTCG
CCGAGTTCGCCGCACGCGCCAGGCGCCTGATCGTCGGCGATCCGCAGGACCCGAAGACCCAGGTCGGCTCGATGATCACC
CAGGCCCACTACGACAAGGTCACCGGCTACATCCGCATCGGCCTCGAGGAAGGCGCCACCCTGGTGGCCGGCGGCCTGGA
GCGTCCGGCCGGCCTGCCGGCGCACCTGAGCAAGGGGCAGTTCATCCAGCCCACGGTGTTCGCCGACGTGGACAACCGCA
TGCGCATCGCCCAGGAGGAGATCTTCGGCCCGGTGGTCTGCCTGATCCCGTTCAAGGACGAAGCCGAGGCGCTGCGCCTG
GCCAACGACGTGGAATACGGCCTGGCCTCCTACATCTGGACCCAGGACATCGGCAAGGCCCATCGCCTGGCACGCGGCAT
CGAGGCCGGGATGGTCTTCATCAACAGCCAGAACGTGCGTGACCTGCGCCAGCCGTTCGGCGGGGTGAAGGCCTCGGGCA
CCGGACGCGAAGGCGGGGAATACAGCTTCGAGGTATTCGCCGAGATCAAGAACGTGTGTATATCCATGGGCAGCCATCAT
ATCCCCCGCTGGGGCGTGTAG

Protein sequence :
MIKHWINGREVESKDVFENYNPATGELIGEVASGGAAEIDAAVAAAREAFPKWANTPAKERARLMRRLGELIDRNVPHLA
ELETLDTGLPIHQTKNVLIPRASHNFEFFAEVCTRMNGHSYPVDDQMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCL
ALGNTAVLKMSELSPLTANELGRLVHEAGIPPGVFNVVQGYGASAGDALVRHRDVRAVSFTGGTATGRRIMEAAGIKKYS
MELGGKSPVLVFEDADLERALDAALFTIFSLNGERCTAGSRIFVQESVYPQFVAEFAARARRLIVGDPQDPKTQVGSMIT
QAHYDKVTGYIRIGLEEGATLVAGGLERPAGLPAHLSKGQFIQPTVFADVDNRMRIAQEEIFGPVVCLIPFKDEAEALRL
ANDVEYGLASYIWTQDIGKAHRLARGIEAGMVFINSQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEIKNVCISMGSHH
IPRWGV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 0.0 79
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-69 42
orf17 AAO17183.1 Orf17 Not tested tcd island Protein 3e-63 41
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-65 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 6e-66 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 6e-66 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 6e-66 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
M062_21745 YP_008134756.1 betaine-aldehyde dehydrogenase VFG0082 Protein 5e-66 41