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Name : leuS (M062_21070) Accession : YP_008134621.1 Strain : Pseudomonas aeruginosa RP73 Genome accession: NC_021577 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : - COG ID : - EC number : 6.1.1.4 Position : 4533924 - 4536545 bp Length : 2622 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCACGAGCAATATCAGCCACTCGAGATCGAAACCCAGGCCCAGAACTACTGGAAAGAACACCAGTCCTTCCTCGTCAG GGAGCTACCCGACAAGGAGAAGTTCTACTGCCTGTCGATGTTCCCGTATCCGAGCGGCAAGTTGCACATGGGCCACGTGC GCAACTACACCATCGGCGACGTGATCAGCCGCTACCACCGCATGCAGGGCCGCAACGTGCTGCAGCCGATGGGCTGGGAC GCGTTCGGCATGCCGGCGGAAAACGCCGCGATGAAGAACAACGTCGCCCCGGCGGCCTGGACCTACGACAACATCGCCTA CATGAAGTCGCAGCTGGACAGCCTCGGCCTGGCGATCGACTGGAGCCGCGAGGTCACCACCTGCAAGCCGGACTACTACC GCTGGGAGCAGTGGCTGTTCACCCGCCTGTTCGAAAAAGGGGTGATCTACCGCAAGAACGGCACGGTCAATTGGGATCCG GTCGACCAGACCGTACTCGCCAACGAGCAGGTGATCGACGGGCGCGGCTGGCGCTCCGGCGCGCTGATCGAGAAGCGCGA GATCCCGATGTACTACTTCAAGATCACCGCCTACGCCGAGGAACTGCTGGAGAGCCTCGACAACCTGCCTGGCTGGCCGG AGCAGGTGAAGACCATGCAGCGCAACTGGATCGGCAAGTCGCGCGGGATGGAGATCGGCTTCCCCTACGACCAGGCCTCC ATCGGCCACGCCGGCCAACTGAAGGTGTTCACCACCCGTCCGGACACCCTGATGGGCGCCACCTACGTCGCCGTCGCCGC CGAACACCCGCTGGCCACCCAGGCAGCGCAGAACGACCCGCAGTTGCAGGCGTTCATCGACGAATGCAAGCGCGGCGGCG TCGCCGAGGCCGACATCGCCACCCAGGAGAAGAAAGGCATGGCCACTTCCCTGTTCGTCGAACACCCGCTGACCGGCGAC AAGCTGCCGGTATGGGTCGCCAACTACGTGCTGATGAACTACGGCGAAGGCGCGGTGATGGCGGTGCCCGGCCATGACGA GCGCGACTTCGAGTTCGCCAACAAGTACGGCCTGCCGATCCGCCAGGTGATCGCCAAGGTCGAGGGCGACAACGACTTCG AGTCCAGCGTCTGGAAGGAGTGGTACGGCGCCAAGGACGAGTCCGTGCTCACCGTCAACTCCGGCAAGTACGACAACCTC GGCTACCAGGCCGCCTTCGACGCCATCGGCGCCGACCTCGAGGCCAAGGGCCTGGGCCAGGCGCGCACCCAGTTCCGCCT GCGCGACTGGGGCATCAGCCGCCAGCGCTACTGGGGCTGCCCGATCCCGATCATCCACTGCGAGGCTTGCGGCGACGTCC CGGTGCCGGCCGACCAGTTGCCGGTGGTGCTGCCGGAAGACGTGGTACCGGACGGCTCCGGTTCGCCGCTGGCGAAGATG CCGGAATTCTACGAATGCAACTGCCCGAAATGCGGCCAGCCGGCCAAGCGCGAAACCGACACCATGGACACCTTCGTCGA GTCGTCCTGGTATTTCGCCCGCTACGCCTGCCCGCAGTTCGAAGGCGGCATGCTGGACAGGAAGGCGGCCGACTACTGGC TGCCGGTCGACCAGTACATCGGCGGCATCGAGCACGCCATCCTGCACCTGCTCTATGCGCGCTTCTTCCACAAGCTGATG CGCGACGAAGGCCTGGTCGGCAGCGACGAACCGTTCAAGAACCTGCTGACCCAGGGCATGGTGGTCGCCGATACCTACTA CCGGACCACCGCCAACGGCGGCAAGGACTGGTTCAACCCGGCCGACGTCGAGGTCGAGCGTGACGCCAAGGCCAAGGTCG TCGGCGCGCGCCTGAAGAGCGACGGCCAGCCGGTCGAGATCGGCGGCACCGAGAAGATGTCGAAGTCGAAGAACAACGGC GTCGACCCGCAATCGATGATCGACCAGTACGGTGCCGATACCTGCCGCCTGTTCATGATGTTCGCCTCGCCGCCGGACAT GAGCCTGGAGTGGTCGGACGCCGGCGTCGAGGGCGCCAACCGCTTCCTCCGCCGCGTCTGGCGCCTGGCTCACGCCCACG TCAGCGCCGGCCTCCCCGGCGCGCTGGACGTCGCCGCCCTGAGCGACGCGCAGAAGCAGGTCCGCCGCGCCATCCACCTG GCGATCAGGCAGGCCAGCCAGGATGTCGGCCAGCACCACAAGTTCAACACCGCCATCGCCGCGGTGATGACCCTGATGAA CGTGCTGGAGAAGGCGCCGAACCAGGACGCCCAGGACCGCGCCCTGATCCAGGAAGGCCTGGAAACCGTGGTCCTGCTGC TGGCGCCCATCACTCCGCACATCTGCCACGTGCTCTGGGGCCAGCTCGGCCATGCCGAAGCGGTGATCGATGCGCGCTGG CCGAGCGTCGACGAGAGCGCACTGGTGCAGGACACCCTGCAACTGGTGGTGCAGGTCAACGGCAAGCTGCGCGGACACAT CGACGTGGCCGCCAGCGCCAGCCGCGAGGATGTCGAGGCCGCCGCGCGCGCCAACGAGAACGTGCTGCGTTTCACCGAAG GCCTGAGCATCCGCAAGGTCATCGTGGTACCGGGCAAACTGGTCAACATCGTCGCCAACTGA Protein sequence : MHEQYQPLEIETQAQNYWKEHQSFLVRELPDKEKFYCLSMFPYPSGKLHMGHVRNYTIGDVISRYHRMQGRNVLQPMGWD AFGMPAENAAMKNNVAPAAWTYDNIAYMKSQLDSLGLAIDWSREVTTCKPDYYRWEQWLFTRLFEKGVIYRKNGTVNWDP VDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITAYAEELLESLDNLPGWPEQVKTMQRNWIGKSRGMEIGFPYDQAS IGHAGQLKVFTTRPDTLMGATYVAVAAEHPLATQAAQNDPQLQAFIDECKRGGVAEADIATQEKKGMATSLFVEHPLTGD KLPVWVANYVLMNYGEGAVMAVPGHDERDFEFANKYGLPIRQVIAKVEGDNDFESSVWKEWYGAKDESVLTVNSGKYDNL GYQAAFDAIGADLEAKGLGQARTQFRLRDWGISRQRYWGCPIPIIHCEACGDVPVPADQLPVVLPEDVVPDGSGSPLAKM PEFYECNCPKCGQPAKRETDTMDTFVESSWYFARYACPQFEGGMLDRKAADYWLPVDQYIGGIEHAILHLLYARFFHKLM RDEGLVGSDEPFKNLLTQGMVVADTYYRTTANGGKDWFNPADVEVERDAKAKVVGARLKSDGQPVEIGGTEKMSKSKNNG VDPQSMIDQYGADTCRLFMMFASPPDMSLEWSDAGVEGANRFLRRVWRLAHAHVSAGLPGALDVAALSDAQKQVRRAIHL AIRQASQDVGQHHKFNTAIAAVMTLMNVLEKAPNQDAQDRALIQEGLETVVLLLAPITPHICHVLWGQLGHAEAVIDARW PSVDESALVQDTLQLVVQVNGKLRGHIDVAASASREDVEAAARANENVLRFTEGLSIRKVIVVPGKLVNIVAN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 5e-139 | 41 |
