Gene Information

Name : guaA (M062_19925)
Accession : YP_008134394.1
Strain : Pseudomonas aeruginosa RP73
Genome accession: NC_021577
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 4284332 - 4285909 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.

DNA sequence :
ATGTCCCAAGACATTCACGCCCACCGTATCCTGATCCTCGATTTCGGCTCCCAGTACACCCAACTGATCGCCCGCCGCGT
GCGCGAGATCGGCGTGTATTGCGAAATCCATCCCTTCGACATGAGCAACGAGGCGATCATCGCCTTCGCGCCGCGCGGCA
TCATCCTCGCCGGTGGCCCCGAGTCGGTACACGAAGCCGACAGCCCGCGCGCGCCGCAGGCGGTGTTCGACCTGAAGGTG
CCGCTGTTCGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAGATGGGCGGCAAGGTGCAGGGCTCCGACCTGCGCGA
GTTCGGCTACGCCCGCGTCGACGTGGTCGGCAAGGCGCGCCTGCTGGACGGCATCGAGGACCACGTGGACGACGACGGCG
TGCTCGGCCTCGACGTGTGGATGAGCCACGGCGACAAGGTCACCGAGATGCCGGCCGGCTTCCACATCCTGGCCAGCACC
CCGAGCTGCCCGATCGCCGCCATGGCCGACGATGCCCGCGCCTACTACGGCGTGCAATTCCACCCGGAAGTCACCCACAC
CAAGCAGGGCCTGCGCATTCTCTCGCGCTTCGTCCTCGACATCTGCGGTTGCGCCGCGCTGTGGACCCCCTCGAACATCG
TCGACGACGCCATCGCCACCGTGCGCGCCCAGGTCGGTTCCTCCAAGGTCCTGCTAGGCCTCTCCGGCGGCGTGGACTCC
TCGGTGGTCGCCGCGCTGCTGCACAAGGCCATCGGCGACCAACTGACCTGCGTGTTCGTCGACAACGGCCTGCTGCGCCT
GCACGAAGGCGACCAGGTGATGGCCATGTTCGCCGAGAACATGGGCGTGAAGGTGATCCGCGCCAACGCCGAGGACAAGT
TCCTCGGCCGCCTGGCCGGCGTCGCCGACCCGGAAGAGAAGCGCAAGATCATCGGCCGCACCTTCATCGAAGTTTTCGAC
GAAGAAGCCACCAAGCTGCAGGACGTGAAGTTCCTCGCCCAGGGCACCATCTACCCCGACGTGATCGAGTCGGCCGGCGC
CAAGACCGGCAAGGCCCACGTGATCAAGTCGCACCACAACGTCGGCGGCCTGCCGGAGGACATGCAGTTCGAACTGGTCG
AGCCGCTGCGCGAACTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAGCTGGGCCTGCCCTACGACATGGTCTACCGC
CACCCGTTCCCCGGCCCGGGCCTGGGCGTGCGCATCCTCGGCGAGGTGAAGAAGGAGTACGCCGACCTGCTGCGCCAGGC
CGACCACATCTTCATCGAGGAACTGCGCGCCTTCGACTGGTACCACAAGACCAGCCAGGCGTTCGTGGTGTTCCAGCCAG
TGAAATCGGTCGGCGTGGTCGGCGACGGCCGTCGCTACGCCTGGGTCGTCGCCCTGCGCGCGGTGGAGACCATCGACTTC
ATGACCGCGCGCTGGGCGCACCTGCCCTACGAACTGCTGGAGAAGGTCTCGAACCGCATCATCAACGAGATTGCCGGTAT
CTCCCGGGTCACCTACGACGTGTCGAGCAAGCCGCCGGCGACTATCGAGTGGGAGTGA

Protein sequence :
MSQDIHAHRILILDFGSQYTQLIARRVREIGVYCEIHPFDMSNEAIIAFAPRGIILAGGPESVHEADSPRAPQAVFDLKV
PLFGICYGMQTMAEQMGGKVQGSDLREFGYARVDVVGKARLLDGIEDHVDDDGVLGLDVWMSHGDKVTEMPAGFHILAST
PSCPIAAMADDARAYYGVQFHPEVTHTKQGLRILSRFVLDICGCAALWTPSNIVDDAIATVRAQVGSSKVLLGLSGGVDS
SVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMAMFAENMGVKVIRANAEDKFLGRLAGVADPEEKRKIIGRTFIEVFD
EEATKLQDVKFLAQGTIYPDVIESAGAKTGKAHVIKSHHNVGGLPEDMQFELVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADLLRQADHIFIEELRAFDWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDF
MTARWAHLPYELLEKVSNRIINEIAGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-122 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-122 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-122 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-108 49