Gene Information

Name : M062_15940 (M062_15940)
Accession : YP_008133611.1
Strain : Pseudomonas aeruginosa RP73
Genome accession: NC_021577
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 3423348 - 3424112 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; Derived by automated computational analysis using gene prediction method:

DNA sequence :
ATGACCCAGGCGTTCACTGTCGTCATTCCCGCCCGCTACGCCTCCACTCGTCTGCCCGGCAAGCCATTGCAGGATATCGC
CGGCCAGCCAATGATCCAGCGCGTCTGGAACCAGGCCCGCAAGAGCGCCGCCAGCCGCGTGGTCGTCGCCACCGACGACG
AACGCATCCTGGCGGCGTGCCAGGGGTTCGGCGCCGAGGCGCTGCTGACACGTGCCGAGCACAACTCCGGCACCGATCGC
CTGGAGGAAGTCGCTTCCCGGCTCGGCCTGGCCAGCGATGCCATCGTGGTCAACGTCCAGGGCGACGAGCCGCTGATCCC
CCCGGCGCTCATCGACCAGGTGGCGGCCAACCTGGCGGCGCACCCGGAGGCCGCCATCGCTACCCTGGCCGAGCCGATCC
ATGAGGTCTCCGCGCTGTTCAATCCGAACGTGGTCAAGGTCGCCACCGACATCGACGGCCTGGCCCTGACTTTCAGTCGT
GCGCCCTTGCCCTGGGCTCGCGACGCCTTCGCCCGCGATCGCGACAGCCTGCCGGAGGGCGTGCCCTATCGTCGCCACAT
CGGCATCTACGCCTATCGCGTGGGTTTCCTTGCCGATTTCGTCGCCTGGGGACCGTGCTGGCTGGAGAACGCCGAAAGCC
TCGAGCAATTGCGCGCGCTCTGGCACGGGGTGCGAATCCATGTGGCCGATGCCCGCGAAACCATGCTTCCGGGCGTGGAT
ACGCCGGAAGACCTCGAACGCGTTCGCCGCGTGCTGGGGGGCTGA

Protein sequence :
MTQAFTVVIPARYASTRLPGKPLQDIAGQPMIQRVWNQARKSAASRVVVATDDERILAACQGFGAEALLTRAEHNSGTDR
LEEVASRLGLASDAIVVNVQGDEPLIPPALIDQVAANLAAHPEAAIATLAEPIHEVSALFNPNVVKVATDIDGLALTFSR
APLPWARDAFARDRDSLPEGVPYRRHIGIYAYRVGFLADFVAWGPCWLENAESLEQLRALWHGVRIHVADARETMLPGVD
TPEDLERVRRVLGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-36 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-36 44
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-36 44