Gene Information

Name : mecR1 (CA347_40)
Accession : YP_008126924.1
Strain : Staphylococcus aureus CA-347
Genome accession: NC_021554
Putative virulence/resistance : Resistance
Product : methicillin resistance mecR1 protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 46228 - 47883 bp
Length : 1656 bp
Strand : +
Note : -

DNA sequence : 
ATGTCACATAAGATTTGGTTATTAGTGCTCGTCTCCACGTTAATTCCATTAATACCATTTTACAAAATATCGAATTTTAC
ATTTTCAAAAGATATGATGAATCGAAATGTATCTGACACGACTTCTTCGGTTAGTCATATGTTAGATGGTCAACAATCAT
CTGTTACGAAAGACTTAGCAATTAATGTTAATCAGTTTGAGACCTCAAATATAACGTATATGATTCTTTTGATATGGGTA
TTTGGTAGTTTGTTGTGCTTATTTTATATGATTAAGGCATTCCGACAAATTGATGTTATTAAAAGTTCGTCATTGGAATC
GTCATATCTTAATGAACGACTTAAAGTATGTCAAAGTAAGATGCAGTTCTACAAAAAGCATATAACAATTAGTTATAGTT
CAAACATTGATAATCCGATGGTATTTGGTTTAGTGAAATCCCAAATTGTACTACCAACTGTCGTAGTCGAAACCATGAAT
GACAAAGAAATTGAATATATTATTCTACATGAACTATCACATGTGAAAAGTCATGACTTAATATTCAACCAGCTTTATGT
TGTTTTTAAAATGATATTCTGGTTTAATCCTGCACTATATATAAGTAAAACAATGATGGACAATGACTGTGAAAAAGTAT
GTGATAGAAACGTTTTAAAAATTTTGAATCGCCATGAACATATACGTTATGGTGAATCGATATTAAAATGCTCTATTTTA
AAATCTCAGCACATAAATAATGTGGCAGCACAATATTTACTAGGTTTTAATTCAAATATTAAAGAACGTGTTAAGTATAT
TGCACTTTATGATTCAATGCCTAAACCTAATCGAAACAAGCGTATTGTTGCGTATATTGTATGTAGTATATCGCTTTTAA
TACAAGCACCGTTACTATCTGCACATGTTCAACAAGACAAATATGAAACAAATGTATCATATAAAAAATTAAATCAACTA
GCTCCGTATTTCAAAGGATTTGATGGAAGTTTTGTGCTTTATAATGAACGGGAGCAAGCTTATTCTATTTATAATGAACC
AGAAAGTAAACAACGATATTCACCTAATTCTACTTACAAAATTTATTTAGCGTTAATGGCATTCGACCAAAATTTACTCT
CATTAAATCATACTGAACAACAATGGGATAAACATCAATATCCATTTAAAGAATGGAACCAAGATCAAAATTTAAATTCT
TCAATGAAATATTCAGTAAATTGGTATTACGAAAATTTAAACAAACATTTAAGACAAGATGAGGTTAAATCTTATTTAGA
TCTAATTGAATATGGTAATGAAGAAATATCAGGGAATGAAAATTATTGGAATGAATCTTCATTAAAAATTTCTGCAATAG
AACAGGTTAATTTGTTGAAAAATATGAAACAACATAACATGCATTTTGATAATAAGGCTATTGAAAAAGTTGAAAATAGT
ATGACTTTGAAACAAAAAGATACTTATAAATATGTAGGTAAAACTGGAACAGGAATCGTGAATCACAAAGAAGCAAATGG
ATGGTTCGTAGGTTATGTTGAAACGAAAGATAATACGTATTATTTTGCTACACATTTAAAAGGCGAAGACAATGCGAATG
GCGAAAAAGCACAACAAATTTCTGAGCGTATTTTAAAAGAAATGGAGTTAATATAA

Protein sequence : 
MSHKIWLLVLVSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFETSNITYMILLIWV
FGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKKHITISYSSNIDNPMVFGLVKSQIVLPTVVVETMN
DKEIEYIILHELSHVKSHDLIFNQLYVVFKMIFWFNPALYISKTMMDNDCEKVCDRNVLKILNRHEHIRYGESILKCSIL
KSQHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISLLIQAPLLSAHVQQDKYETNVSYKKLNQL
APYFKGFDGSFVLYNEREQAYSIYNEPESKQRYSPNSTYKIYLALMAFDQNLLSLNHTEQQWDKHQYPFKEWNQDQNLNS
SMKYSVNWYYENLNKHLRQDEVKSYLDLIEYGNEEISGNENYWNESSLKISAIEQVNLLKNMKQHNMHFDNKAIEKVENS
MTLKQKDTYKYVGKTGTGIVNHKEANGWFVGYVETKDNTYYFATHLKGEDNANGEKAQQISERILKEMELI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mecR1 NP_373279.1 methicillin resistance protein Not tested Type-II SCCmec Protein 0.0 100
mecR1 YP_190061.1 methicillin-resistance regulatory protein MecR1 Not tested Type-II SCCmec Protein 0.0 100
mecR1 BAA82219.2 sensor transducer protein MecR1 Not tested Type-II SCCmec Protein 0.0 100
mecR1 YP_039516.1 methicillin resistance protein MecR1 Not tested Type-II SCCmec Protein 0.0 100
mecR1 NP_370566.1 methicillin resistance protein Not tested Type-II SCCmec Protein 0.0 100
mecR1 BAC57479.1 signaltransducer protein MecR1 Not tested Type-IIIinv SCCmec Protein 0.0 99
mecR1 YP_005754042.1 methicillin resistance protein MecR1 Not tested Type-XI SCCmec Protein 4e-129 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mecR1 YP_008126924.1 methicillin resistance mecR1 protein NC_002745.1122813.p0 Protein 0.0 100
mecR1 YP_008126924.1 methicillin resistance mecR1 protein NC_002952.2861159.p0 Protein 0.0 100
mecR1 YP_008126924.1 methicillin resistance mecR1 protein NC_002758.1120002.p0 Protein 0.0 100
mecR1 YP_008126924.1 methicillin resistance mecR1 protein NC_009782.5560215.p0 Protein 0.0 100
mecR1 YP_008126924.1 methicillin resistance mecR1 protein HE993884.1.gene10.p0 Protein 4e-123 48
mecR1 YP_008126924.1 methicillin resistance mecR1 protein FR823292.1.gene4.p01 Protein 2e-129 45