Gene Information

Name : hlgA (CA347_2499)
Accession : YP_008129295.1
Strain : Staphylococcus aureus CA-347
Genome accession: NC_021554
Putative virulence/resistance : Virulence
Product : gamma-hemolysin component A
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2530211 - 2531140 bp
Length : 930 bp
Strand : +
Note : -

DNA sequence :
ATGATTAAAAATAAAATATTAACAGCAACTTTAGCAGTTGGTTTAATCGCCCCTTTAGCCAATCCATTTATAGAAATTTC
TAAAGCAGAAAATAAGATAGAAGATATCGGCCAAGGTGCAGAAATCATCAAAAGAACACAAGACATTACTAGCAAACGAT
TAGCTATAACTCAAAACATTCAATTTGATTTTGTAAAAGATAAAAAATATAACAAAGATGCCCTAGTTGTTAAGATGCAA
GGCTTCATCAGCTCTAGAACAACATATTCAGACTTAAAAAAATATCCATATATTAAAAGAATGATATGGCCATTTCAATA
TAATATCAGTTTGAAAACGAAAGACTCTAATGTTGATTTAATCAATTATCTTCCTAAAAATAAAATTGATTCAGCAGATG
TTAGTCAGAAATTAGGCTATAATATCGGTGGAAACTTCCAATCAGCGCCATCAATCGGAGGCAGTGGCTCATTCAACTAC
TCTAAAACAATTAGTTATAATCAAAAAAACTATGTTACTGAAGTAGAAAGTCAGAACTCTAAAGGTGTTAAATGGGGAGT
GAAAGCAAATTCATTCGTTACACCGAATGGTCAAGTATCTGCATATGATCAATACTTATTTGCACAAGACCCAACTGGTC
CAGCAGCAAGAGACTATTTCGTCCCAGATAATCAACTACCTCCTTTAATTCAAAGTGGCTTTAATCCATCATTTATTACA
ACATTGTCACACGAAAAAGGTAAAGGTGATAAAAGCGAGTTTGAAATCACTTACGGCAGAAACATGGATGCTACATATGC
ATACGTGACAAGACATCGTTTAGCCGTTGATAGAAAACATGATGCTTTTAAAAACCGAAACGTTACAGTTAAATATGAAG
TGAACTGGAAAACACATGAAGTAAAAATTAAAAGCATCACACCTAAGTAA

Protein sequence :
MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQ
GFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNY
SKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPPLIQSGFNPSFIT
TLSHEKGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 5e-106 71
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 5e-106 71
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 5e-106 71
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 5e-106 71
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 5e-106 71
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 5e-106 71
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 4e-106 71
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 4e-95 67
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 4e-95 67
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 3e-98 67

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hlgA YP_008129295.1 gamma-hemolysin component A VFG1273 Protein 1e-141 99
hlgA YP_008129295.1 gamma-hemolysin component A VFG1274 Protein 3e-90 69
hlgA YP_008129295.1 gamma-hemolysin component A VFG1277 Protein 2e-95 67