Gene Information

Name : K756_03780 (K756_03780)
Accession : YP_008123529.1
Strain : Haemophilus parasuis ZJ0906
Genome accession: NC_021521
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 719890 - 721809 bp
Length : 1920 bp
Strand : +
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGCGTTTATTCATTGCAGAAAAGCCAAGTTTAGGGCGTGCGATTGCTGATGTATTGCCGAAACCCCATACCCGTGGGGA
CGGCTTTATTCAGTGTGGCGAAGACAATGTGGTTACTTGGTGTATCGGTCACTTGTTAGAACAAGCTGAACCTGATGCTT
ATGATGAACGTTTCAAAATGTGGCGAATGGAACATTTGCCGATTATCCCTGAACAGTGGAAGCTGATCCCCAAAAAAGAG
ACACTCAAGCAGTTTAAGGTGGTAGAGCGTTTAATTAAACAAGCGGATATTTTAGTCAATGCAGGCGACCCAGATCGTGA
AGGACAACTGTTGGTGGACGAAGTTTTTGGCTACTTAAATTTATCCCCTGAGCGGAAATCCCAAATTCAGCGGTGTTTGA
TTAGCGATCTCAACCCTAATGCTGTCAAAAAAGCGATTGAAAAATTGCAATTTAATCGAGATTTCGTACCGCTTGCTACA
TCGGCTTTAGCTCGTGCAAGGGCAGACTGGCTATATGGGATCAATATGACCAGAGCCTATACGCTACAAGGGCGTTGGGC
AGGTTATAAAGGCGTGCTTTCCGTTGGACGTGTACAAACGCCAGTGTTGGGCTTGATTGTCCGACGTGATCTTGAGATCG
AAAATTTTATCCCAAAAGATTATTTTGAAGTGTTGGCAAATGTGGTTGTCTCTGAAACCCAAGAGCTTTTTCAAGCACAA
TGGCAACCAAGTAAAGCCTGCGAAGATTATCAAGATGAAGATGGACGAGTACTTTCTCGCCCACTTGCTGAGAATGTGGT
AAAACGTATCGCCGATCAAGCCGCTTGCGTTACCGAATATCAAGATAAAATGGAAAGTGAAGCAGCACCACTCCCTTATT
CACTCTCAGCCTTGCAAATTGATGCGGCTCGCCGTTTTGGCTTATCTGCCCAAGATGTGCTTGATGTTTGCCAACGGCTG
TATGAAACCCATAAATTGATTACTTACCCTCGTTCCGACAACCGTTATTTGCCGAATGAACATTTTGCCGACCGCCTAAA
AGTGATGGCGGCAATTGCTTATCATCTGCCTGAGTATGCTCAAAAGCCCGATGCTGTTGATCCGAATAAGAAAAACCGTT
GCTGGAATGACAGTAAGGTAGAAGCCCACCACGCTATTATCCCAACGGCACGTCAAGGGCAAGTTCACTTAACCCAAAAT
GAACAGCGGATTTATCAGCTTATTGCTCGACAATATTTAATGCAGTTTTGCCCTGACGCAGAATATCGTAAAGGAAAAAT
TGTGTTAAATATCGCAGGGGGGACTTTTGTTGCGCAAGCCAGAAACCTTGTTGTTGCAGGTTGGAAGTCCTTGTTAGGCA
AAGAAGATAATGATGAAATCGTTGAACCTTTGCTACCTGTGGTTAAAAAAGATCAGCAGTTATGGTGTGAAAGCGGTGAG
ATCGTCAGCAAAAAAACACAGCCCCCACGCCATTTTACTGATGCGACCTTGTTATCCGCAATGACGGGCATTGCTCGCTT
TGTACAGGATAAACAGCTCAAAAAAGTGTTGAGGGAAACCGACGGCTTGGGTACAGAAGCCACCCGAGCTGGTATTATTG
AATTATTATTCAAACGTGGCTTTTTAATCAAAAAAGGCAGAAACATTCATAGTACAGAAGCAGGACGAACCTTAATTAGT
GCCTTGCCAGATGTTGCAACACAGCCTGATATGACAGCTCACTGGGAAATGCAACTAACAGACATCAGCAAAAAACAAGC
CAGTTATCAACAATTTATGGCAGATTTAAACCAACGATTGCCGAGTTTATTACGTTCTCCAAATCAGCAGATTTTGCAAA
ATTTGGCGAAAATAACACCGCTTACAATGGGTTCTAAATCACGTTATGCCCGTAAATCTACGCAAAATGTTGAAAAATAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHTRGDGFIQCGEDNVVTWCIGHLLEQAEPDAYDERFKMWRMEHLPIIPEQWKLIPKKE
TLKQFKVVERLIKQADILVNAGDPDREGQLLVDEVFGYLNLSPERKSQIQRCLISDLNPNAVKKAIEKLQFNRDFVPLAT
SALARARADWLYGINMTRAYTLQGRWAGYKGVLSVGRVQTPVLGLIVRRDLEIENFIPKDYFEVLANVVVSETQELFQAQ
WQPSKACEDYQDEDGRVLSRPLAENVVKRIADQAACVTEYQDKMESEAAPLPYSLSALQIDAARRFGLSAQDVLDVCQRL
YETHKLITYPRSDNRYLPNEHFADRLKVMAAIAYHLPEYAQKPDAVDPNKKNRCWNDSKVEAHHAIIPTARQGQVHLTQN
EQRIYQLIARQYLMQFCPDAEYRKGKIVLNIAGGTFVAQARNLVVAGWKSLLGKEDNDEIVEPLLPVVKKDQQLWCESGE
IVSKKTQPPRHFTDATLLSAMTGIARFVQDKQLKKVLRETDGLGTEATRAGIIELLFKRGFLIKKGRNIHSTEAGRTLIS
ALPDVATQPDMTAHWEMQLTDISKKQASYQQFMADLNQRLPSLLRSPNQQILQNLAKITPLTMGSKSRYARKSTQNVEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 4e-109 42
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 4e-109 42
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 3e-109 42
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-108 42
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 4e-104 41
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-105 41