Gene Information

Name : H650_01040 (H650_01040)
Accession : YP_008106063.1
Strain : Enterobacter sp. R4-368
Genome accession: NC_021500
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 85508 - 87028 bp
Length : 1521 bp
Strand : +
Note : catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGAAATATGTCCACCCTGGCCTTGATGGCGCGAAAGTCTCTTTTAAACAGCGTTATGGCAACTATATTGGCGGTGAATT
TGTTGACCCGGTGGAAGGGCGTTGGTTTACCAACACCTCGCCGGTCACCGGACAGGTGATTGCCGAATTCCCGCGCTCAG
ACGCGGCGGATATTGAGAAGGCTCTGGACGCAGCGCATGCTGCCGCCGACGCCTGGGGAAAAACCAGCGTGCAGGATCGC
GCCAATGTGCTGCTGGCCATTGCCGATCGCATCGAAGCCAACCTGGAAATGCTGGCATTAACAGAAACCTGGGATAACGG
AAAACCGATCCGCGAAACCATGGGCGCGGATTTGCCGCTGGCTGTTGATCACTTCCGTTATTTCGCCGGTTGTATCCGCG
CGCAGGAAGGGACAGCGGCAGAGATCGACAGCAATACGGTTGCTTACCACATCTATGAACCGCTGGGCGTGGTCGGGCAG
ATCATTCCGTGGAACTTCCCGCTGCTGATGGCGGCGTGGAAACTGGCGCCGGCGCTGGCGGCGGGTAACTGCGTGGTACT
GAAACCGGCTGAACAGACGCCGCTTGGCATCTGCGTGTTGATGGAACTGATTGGCGATCTGCTACCCAAAGGTGTGCTGA
ATGTGGTGCACGGCTTCGGCACTGAAGCCGGTGAACCGCTGGCGCGCAGCAAACGCATCGAAAAAATCGCCTTTACCGGC
TCCACGCCGATTGGCCGCCACATCCTTTCGTGCGCGGCGGAAAACATCATCCCCAGCACCGTCGAGCTCGGCGGGAAATC
ACCGAATATTTACTTCGAAGATGTGATGAATGGTGATGAAGGCTTTATTGATAAAGCGGTGGAAGGCGTGGTGCTCGGCT
TCTTCAACCAGGGCGAAGTCTGCACCTGCCCGTCGCGCGTGCTGGTGCAGGAATCGATCTACCCGCAGTTTGTCGAAAAA
GTCATCGCCCGCATGGAGAACATCCGCAAAGGCGACCCGTTTGACACCGACACCATGATTGGTGCGCAGGCGTCACAAGA
GCAGTACGACAAGATCCTCTCTTACATCTCGATTGCCCGCGACGAAGGCGGCGAAATCATTACCGGCGGCGCTCACGTGG
AACACGGCGACGGGCTGCAAAACGGTTTCTATATCCAGCCGACATTGATTAAAGGCCATAACGGGATGCGTTGCTTCCAG
GAAGAGATTTTTGGGCCGGTGCTGGGCATTACCACCTTTAAAGATGAAGCCGAAGCGCTGCGTATCGCCAACGACACCGA
GTTTGGCCTCGGCGCCGGGGTGTGGACGCTGGATATCAATCGCGCATGGCGCATGGGGCGCGGCATTAAAGCGGGTCGCG
TATGGACAAACTGTTACCACCTCTACCCGGCACATGCGGCGTTTGGCGGTTACAAAAACTCGGGCGTCGGGCGTGAAACC
CACAAACTGGCGCTGAGCCACTATCAGCAGATCAAAAACCTGCTGGTGAGTTACAGCGGTTCGCCGCTGGGGCTGTATTA
A

Protein sequence :
MKYVHPGLDGAKVSFKQRYGNYIGGEFVDPVEGRWFTNTSPVTGQVIAEFPRSDAADIEKALDAAHAAADAWGKTSVQDR
ANVLLAIADRIEANLEMLALTETWDNGKPIRETMGADLPLAVDHFRYFAGCIRAQEGTAAEIDSNTVAYHIYEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLGICVLMELIGDLLPKGVLNVVHGFGTEAGEPLARSKRIEKIAFTG
STPIGRHILSCAAENIIPSTVELGGKSPNIYFEDVMNGDEGFIDKAVEGVVLGFFNQGEVCTCPSRVLVQESIYPQFVEK
VIARMENIRKGDPFDTDTMIGAQASQEQYDKILSYISIARDEGGEIITGGAHVEHGDGLQNGFYIQPTLIKGHNGMRCFQ
EEIFGPVLGITTFKDEAEALRIANDTEFGLGAGVWTLDINRAWRMGRGIKAGRVWTNCYHLYPAHAAFGGYKNSGVGRET
HKLALSHYQQIKNLLVSYSGSPLGLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-145 67
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-152 66
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-152 66
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-152 66
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-151 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
H650_01040 YP_008106063.1 aldehyde dehydrogenase VFG0082 Protein 5e-146 67