Gene Information

Name : H650_23415 (H650_23415)
Accession : YP_008110409.1
Strain : Enterobacter sp. R4-368
Genome accession: NC_021500
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.38
Position : 4755027 - 4755773 bp
Length : 747 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; Derived by automated computational analysis using gene prediction method:

DNA sequence : 
ATGAGTTTCGTTGTTATCATTCCCGCGCGTTATGCTTCCACTCGCTTGCCCGGCAAACCTTTAGTCGACATTAACGGTAA
GCCCATGGTGGTGCATGTGCTGGAGCGCGCCCGTGAATCCGGCGCTGAGCGTATTATCGTGGCGACGGACAACGAAGAGG
TGATGCATGCGGTCCAGGCGGTTGGCGGTGAAGTCTGTATGACTCGCGCCGATCATCAGTCCGGCACTGAACGCCTTGCC
GAAGTCGTGGAAAAATGCGGTTTCAGCGACGATACCGTCATCGTCAATGTGCAGGGTGATGAACCCATGATCCCTCCGGC
GATTATTCGCCAGGTGGCAGAAAATCTTGCCGCGCGTGATGTTGGAATGGCAACGCTGGCGGTACCGATTCACAGCGCGG
AAGAGGCGTTCAACCCGAACGCGGTGAAAGTGGTGATGGACGCCGAGGGTTACGCGCTCTACTTCTCCCGCGCCACGATC
CCCTGGGATCGCGACCGTTTCGCACAATCTCGCGAGACGATTGGCGATACCTTCCTGCGCCATATCGGCATTTATGGCTA
TCGCGCCGGTTTTATCCGCCGTTATGTCAGCTGGCAAACCAGCCCGCTTGAGCAGATAGAGATGCTGGAGCAACTGCGTG
TGCTCTGGTACGGCGAGAAAATCCACGTTGCCGTTGCCAGTGTGGTGCCGGGCACCGGTGTGGATACCCCGGAAGATCTG
GCGCGCGTCCGTCAGGAGCTGCGTTAA

Protein sequence : 
MSFVVIIPARYASTRLPGKPLVDINGKPMVVHVLERARESGAERIIVATDNEEVMHAVQAVGGEVCMTRADHQSGTERLA
EVVEKCGFSDDTVIVNVQGDEPMIPPAIIRQVAENLAARDVGMATLAVPIHSAEEAFNPNAVKVVMDAEGYALYFSRATI
PWDRDRFAQSRETIGDTFLRHIGIYGYRAGFIRRYVSWQTSPLEQIEMLEQLRVLWYGEKIHVAVASVVPGTGVDTPEDL
ARVRQELR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-38 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-38 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 8e-39 45