Gene Information

Name : leuS (H650_22055)
Accession : YP_008110149.1
Strain : Enterobacter sp. R4-368
Genome accession: NC_021500
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.4
Position : 4467476 - 4470058 bp
Length : 2583 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATACCGCCCGGAAGATATAGAATCCAAAGTACAGCGCCACTGGGAAGAGAAGCGCACATTTGAAGTCAC
TGAAGACGAGAGCAAAGAGAAATACTATTGCTTGTCGATGCTCCCCTATCCTTCTGGCCGACTACACATGGGCCACGTCC
GTAACTACACCATCGGCGATGTGATCTCCCGTTATCAGCGCATGCTGGGTAAAAACGTGCTGCAGCCGATTGGCTGGGAT
GCGTTTGGTCTGCCGGCTGAAGGCGCGGCGGTAAAAAATAACACCGCACCGGCACCGTGGACTTACGACAACATCGCGTA
CATGAAAAACCAGCTCAAAATGCTGGGTTTCGGCTATGACTGGAGCCGCGAGCTGGCGACCTGCACCCCGGAATATTACC
GTTGGGAACAGAAGTTCTTCACCGAGCTGTACAAAAAAGGTCTCGTCTATAAGAAAACCTCCGCGGTGAACTGGTGCCCG
AACGATCAGACCGTGCTGGCGAACGAACAAGTTATCGACGGCTGCTGCTGGCGCTGCGATACCAAAGTTGAACGCAAAGA
GATCCCGCAGTGGTTTATTAAAATCACCGCTTATGCTGACGAGCTGCTGAATGACCTGGATAATCTGGATCATTGGCCGG
ATACGGTGAAAACCATGCAGCGCAACTGGATTGGCCGTTCTGAAGGCGTGGAGATCACGTTCGACGTGCAGAACAGCGAC
CAGAAACTGACGGTCTACACCACGCGCCCGGACACGTTTATCGGCGCAACTTATCTGGCCGTTGCGGCAGGCCATCCGCT
GGCGCAGCAAGCCGCCGCGAGCAAACCGGAGCTGGCGTCCTTTATCGACGAATGCCGTAACACCAAAGTTGCGGAAGCCG
ATATGGCGACGATGGAGAAAAAAGGCGTTGATACCGGCCTGAAAGCCATTCACCCGCTGACCGGGGAAGCGATTCCGGTA
TGGGCGGCAAACTTTGTGCTGATGGAATACGGCACCGGTGCGGTGATGGCCGTTCCGGGTCACGATCAGCGCGACTACGA
ATTTGCCACGAAATACAATCTGCCGATCAAGGCGGTCATTCTCAACGCTGACGGCAGCGCGCCGGATCTGAGCGAACAAG
CGATGACCGATAAAGGCGTGCTGTTTAACTCTGGCGAATTCGACGGTCTCGACTTTAACGCTGCTTTTAACGCCATTGCC
GACAAACTGGCGGCCAAAGGCGTGGGCGAGCGCAAAGTGAATTTCCGTCTGCGCGACTGGGGCGTTTCCCGTCAGCGTTA
CTGGGGCGCGCCCATCCCGATGGTGACGCTGGAAGATGGCACCGTTATTCCAACGCCGGAAGATCAACTGCCGGTTATCC
TGCCGGAAGATGTTGTCATGGACGGTATCACCAGCCCGATTAAAGCCGATCCTGAGTGGGCGAAAACCACCGTCAACGGC
CAACCGGCGCTGCGCGAAACCGATACCTTCGACACCTTTATGGAGTCTTCCTGGTACTATGCGCGTTACACCTGCCCGCA
GCACAACGAAGGCATGCTGGACCCGAAAGCGGCAAATTACTGGCTGCCGGTAGATATTTATATTGGCGGCATCGAACACG
CCATCATGCACCTGCTCTACTTCCGCTTCTTCCACAAACTGATGCGCGACGCGGGCATGGTGAACTCCGATGAGCCTGCG
AAACAGCTGCTGTGCCAGGGCATGGTACTGGCCGATGCGTTCTATTACGTGGGTGAAAACGGCGAGCGTAACTGGGTTTC
GCCGAAAGATGCCATTGTTGAACGTGACGAAAAAGGGCGCATTGTCAAAGCGACCGATCCGGCAGGCCACGAGCTGGTTT
ATACCGGCATGAGCAAAATGTCCAAGTCGAAAAACAACGGTATCGACCCGCAGGAAATGGTTGAGCGTTACGGCGCGGAC
ACCGTGCGTCTGTTCATGATGTTTGCATCGCCAGCCGATATGACACTGGAGTGGCAGGAATCCGGCGTAGAAGGCGCGAA
CCGCTTCCTGAAACGCGTCTGGAAACTGGTTTATGAACATACCGCTCGGGGTGCTGTTGCCGCACTGGATCTGGCTGCGC
TGAGTGAAGACCAGCAAGCCCTGCGTCGCGACGTGCATAAAACTATCGCGAAAGTTTCCGATGATATTGGTCGTCGTCAG
ACTTTCAACACCGCTATCGCGGCGATTATGGAGCTGATGAACAAACTGGCGAAAGCGCCGCAGGAGAGCGAGCAGGATCG
CGCCTTAATGCAGGAAGCCCTGCTGGCGGTGGTACGTATGCTTAACCCGTTCACCCCACACGCCAGCTTCACGCTGTGGC
AGGAACTGGGCGGCGAAGGCGACATCGACAACGCACCGTGGCCGGTAGCTGATGAGAAAGCGATGGTTGAAAACACCACG
CTGGTTGTCGTCCAGGTCAATGGTAAAGTGCGTGGTAAAATTACTGTTGCCGTTGACGCGACGGAAGAACAGGTGCGTGA
ACGCGCAGGCCAGGAACATCTGGTAGCAAAATATCTTGATGGCGTGACCGTGCGTAAAGTGATTTACGTACCGGGTAAAC
TGCTTAATCTGGTCGTTGGCTAA

Protein sequence :
MQEQYRPEDIESKVQRHWEEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDNLDHWPDTVKTMQRNWIGRSEGVEITFDVQNSD
QKLTVYTTRPDTFIGATYLAVAAGHPLAQQAAASKPELASFIDECRNTKVAEADMATMEKKGVDTGLKAIHPLTGEAIPV
WAANFVLMEYGTGAVMAVPGHDQRDYEFATKYNLPIKAVILNADGSAPDLSEQAMTDKGVLFNSGEFDGLDFNAAFNAIA
DKLAAKGVGERKVNFRLRDWGVSRQRYWGAPIPMVTLEDGTVIPTPEDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
QPALRETDTFDTFMESSWYYARYTCPQHNEGMLDPKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPA
KQLLCQGMVLADAFYYVGENGERNWVSPKDAIVERDEKGRIVKATDPAGHELVYTGMSKMSKSKNNGIDPQEMVERYGAD
TVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTARGAVAALDLAALSEDQQALRRDVHKTIAKVSDDIGRRQ
TFNTAIAAIMELMNKLAKAPQESEQDRALMQEALLAVVRMLNPFTPHASFTLWQELGGEGDIDNAPWPVADEKAMVENTT
LVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-144 41