Gene Information

Name : H650_19710 (H650_19710)
Accession : YP_008109693.1
Strain : Enterobacter sp. R4-368
Genome accession: NC_021500
Putative virulence/resistance : Virulence
Product : lysine decarboxylase CadA
Function : -
COG functional category : -
COG ID : -
EC number : 4.1.1.18
Position : 3981876 - 3984014 bp
Length : 2139 bp
Strand : +
Note : constitutive; catalyzes the formation of cadaverine from lysine; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
GTGAATATTATTGCCATCATGGGACCACATGGCGTTTTCTATAAAGATGAGCCAATTAAGGAGCTTGAGCAGGCATTACA
GGCCCAGGGCTTTCAACTTATCTGGCCGCAAAACAGCACCGACTTACTGAAATTTATCGAACACAACCCGCGCATCTGCG
GCGTTATCTTTGACTGGGATGAGTACTCCCTCGATCTGTGCAGCGAAATCAATCAGCTTAACGAATATCTCCCGCTGTAC
GCCTTTATCAATACCCACTCGACGATGGACGTCAGCATCCAGGATATGCGCATGGCGCTATGGTTTTTCGAGTATGCGCT
GGGTGTGTCCGAGGATATTGCTACGCGTATCGGCCAGTACACCCGCGAGTATCTCGAAACCATCACGCCGCCGTTTACCC
GCGCGCTGTTTACCTACGTTAAAGAAGGCAAATATACCTTTTGTACGCCGGGGCATATGGCGGGCACGGCTTATCAGAAA
AGCCCGGTTGGCTGCCTGTTTTACGATTTTTTCGGTGGCAATACGTTAAAAGCAGATGTCTCTATTTCGGTCACGGAGCT
GGGCTCGTTACTGGATCACACAGGCCCGCATCTGGAAGCCGAAGAGTATATCGCCCGCACCTTTGGCGCGGAGCAGAGCT
ACATGGTGACCAACGGCACCTCGACCTCGAATAAAATCGTCGGCATGTATGCCGCACCGGCCGGCAGCACATTGTTGATT
GATCGTAACTGCCATAAGTCACTGGCACATCTGCTGATGATGAGCGACGTTACGCCGCTATGGCTGAAACCCGGGCGCAA
TGCGCTGGGGATTCTGGGCGGGATCCCTCGTCGTGAATTTACCCATGCCAGCATCGAACAGAAGGTGGCAAAAACGGCGG
GCGCACGCTGGCCGGTACATGCGGTGATCACCAACTCCACTTATGACGGACTGTTGTATAACACCGACTGGATCAAAAAG
ACGCTTGATGTGCCGTCGATCCACTTCGATTCTGCCTGGGTTCCTTATACCAATTTTCACCCGATCTACGCCGGGAAAAG
CGGCATGAGTGGCGAGCGGGTGCCAGGAAAAGTGTTCTTTGAAACCCAGTCGACGCACAAAATGCTGGCGGCATTTTCAC
AGGCATCGCTGATTCATATTAAAGGTGAATATGATGAAGACACCTTTAACGAAGCATTTATGATGCACACCACCACCTCG
CCGAGTTACCCGCTGGTGGCCTCCATCGAAACGGCGGCTGCGATGCTGCGCGGTAATCCCGGCAAACGTCTGATTAACCG
TTCCGTCGAGCGCGCGCTGCATTTCCGTAAAGAAGTTCAGCGGCTGAAAGATGAAGCCGATGGCTGGTTCTTTGATATCT
GGCAGCCAGAAGAGATTGAAGAGGCGGACTGCTGGCCGGTTGCGCCCGGTGAAGCATGGCACGGTTTTCGCGATGCGGAT
GCCGACCATATGTTTCTCGATCCGGTTAAAGTGACCATCCTGACGCCGGGGATGGACGAGCTGGGGAACATGAGTGACGA
GGGGATCCCGGCGGCGCTGGTGGCGAAGTTCCTCGATGAGCGCGGTGTGGTGGTTGAGAAAACCGGGCCATATAACTTGC
TGTTTTTGTTCAGTATTGGCATTGATAAAACCCGCGCGATGGGGTTGCTGCGCGGATTGATGGAGTTTAAACGCGCCTAC
GATCTGAATCTGCGCGTGAAGAATATGCTGCCGGATCTCTACGCCGAAGATCCGGATTTCTACCGCAATATGCGCATTCA
GGATCTGGCTCAGGGGATCCATAAGCTCATCCGCCAGCACGATCTTCCACGTTTAATGCTGCAAGCGTTTGATGTATTAC
CGGAAATGAAACTGACGCCGCACCAGGCCTGGCAGCGGCAAATTCAGGGCGAGGTGGAAACCATTGAGCTTGAGCGACTG
ATAGGACGAATCTCGGCGAATATGATCCTGCCTTATCCGCCAGGCGTGCCGCTGGTGATGCCCGGTGAAATGATCACCGA
AGCGAGCAGAGCCGTGCTGGATTTCCTGCTGATGCTTTGCGCTATTGGCCGCCACTATCCCGGTTTTGAGACGGATATTC
ATGGCGCGAAGCGGGACGAAGAGGGCGTTTATCGGGTACGAGTCCTAAAAAACCGCTGA

Protein sequence :
MNIIAIMGPHGVFYKDEPIKELEQALQAQGFQLIWPQNSTDLLKFIEHNPRICGVIFDWDEYSLDLCSEINQLNEYLPLY
AFINTHSTMDVSIQDMRMALWFFEYALGVSEDIATRIGQYTREYLETITPPFTRALFTYVKEGKYTFCTPGHMAGTAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYMVTNGTSTSNKIVGMYAAPAGSTLLI
DRNCHKSLAHLLMMSDVTPLWLKPGRNALGILGGIPRREFTHASIEQKVAKTAGARWPVHAVITNSTYDGLLYNTDWIKK
TLDVPSIHFDSAWVPYTNFHPIYAGKSGMSGERVPGKVFFETQSTHKMLAAFSQASLIHIKGEYDEDTFNEAFMMHTTTS
PSYPLVASIETAAAMLRGNPGKRLINRSVERALHFRKEVQRLKDEADGWFFDIWQPEEIEEADCWPVAPGEAWHGFRDAD
ADHMFLDPVKVTILTPGMDELGNMSDEGIPAALVAKFLDERGVVVEKTGPYNLLFLFSIGIDKTRAMGLLRGLMEFKRAY
DLNLRVKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRQHDLPRLMLQAFDVLPEMKLTPHQAWQRQIQGEVETIELERL
IGRISANMILPYPPGVPLVMPGEMITEASRAVLDFLLMLCAIGRHYPGFETDIHGAKRDEEGVYRVRVLKNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 70
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
H650_19710 YP_008109693.1 lysine decarboxylase CadA VFG1670 Protein 0.0 61