Gene Information

Name : H650_16555 (H650_16555)
Accession : YP_008109078.1
Strain : Enterobacter sp. R4-368
Genome accession: NC_021500
Putative virulence/resistance : Unknown
Product : phosphomethylpyrimidine synthase ThiC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3283698 - 3285590 bp
Length : 1893 bp
Strand : -
Note : catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGTCTGCAAAACTTACACGCCGTGAACAACGCGCCCAGGCGCAACACTTCATCGACACACTGGAAGGCACCGCTTTCCC
CAACTCGCGCCGCATCTACATCACCGGTTCGCAACCCGATATCCGCATTCCGATGCGCGAAATCCAGCTGAGCCCGACGC
TTACCGGCGGCACAAAAGAACACCCACAGTTTGAAGAGAATGAAGCGGTGCCGGTGTACGACACCTCGGGCCCGTATGGC
GATCCGGATATTGCGATTGATGTCCAGCAAGGGCTGGCGAAACTGCGCGCACCGTGGATTGCCGCCCGTGATGACAGCGA
AACACTGGAACAGCGCAGCTCTGTCTATACCAACGAACGGCTGGCCGATGATGGCCTCGACGAATTGCGTTTTAGCGGTT
TACTGACGCCGCGCCGCGCGAAACCCGGCCAGCGCGTCACGCAACTGCACTATGCGCGCAAAGGCATCGTCACGCCGGAA
ATGGAGTTTATCGCCATTCGCGAAAACATGGGCCGCGAGCGCATTCGCAGCGAAGTGTTGCGTAAGCAGCATCCGGGCGA
AGGTTTTGGCGCACGCCTACCGGAAAACATCACCCCGGAATTTGTGCGCGATGAAGTCGCCGCCGGGCGGGCGATTATCC
CGGCCAATATTAACCACCCGGAATCGGAGCCAATGATCATTGGCCGCAACTTCCTGGTGAAGGTGAACGCCAATATCGGT
AATTCGGCGGTGACTTCCTCGATCGAAGAAGAGGTGGAAAAGCTGGTCTGGTCGACGCGCTGGGGCGCGGACACGGTCAT
GGATTTATCCACCGGGCGTTATATCCACGAAACCCGCGAATGGATCCTGCGTAACAGCCCGGTGCCGATCGGTACAGTGC
CGATCTACCAGGCGCTGGAGAAGGTTAACGGGATCGCCGAAGATCTTACCTGGGAAGCATTTCGCGACACCCTGCTGGAA
CAGGCGGAGCAAGGGGTGGACTATTTCACCATCCACGCGGGCGTGCTGCTGCGCTATGTGCCCATGACCGCGCAGCGCCT
GACCGGCATTGTCTCGCGCGGTGGCTCAATTATGGCGAAATGGTGCCTCTCCCATCATCAGGAAAACTTCCTCTACACCC
ATTTTCGCGAGATCTGCGAAATCTGCGCCGCTTATGACGTTTCGCTATCGCTGGGCGATGGCTTGCGCCCAGGCTCCATT
CAGGACGCCAACGACGAAGCGCAATTTGCCGAGCTGCATACGCTTGGCGAACTGACGAAAATTGCCTGGGAGTATGACGT
TCAGGTGATGATTGAAGGCCCGGGGCATGTACCAATGCAGATGATCCGCCGCAATATGACCGAAGAACTGGAGCACTGCC
ACGAAGCGCCATTCTATACGCTGGGGCCGCTAACCACCGATATCGCGCCGGGCTATGACCATTTCACCTCTGGTATTGGC
GCGGCGATGATTGGCTGGTTTGGCTGCGCGATGCTCTGTTATGTCACGCCCAAAGAGCACCTCGGCTTACCCAATAAAGA
GGACGTTAAACAGGGGCTGATTACCTACAAAATCGCCGCTCACGCCGCTGACCTGGCCAAAGGCCACCCTGGCGCGCAGA
TCCGCGACAACGCCATGTCGAAAGCGCGTTTTGAGTTCCGCTGGGAGGATCAATTCAACCTTGCGCTCGACCCGTTTACC
GCGCGCGCCTACCACGATGAAACGCTGCCGCAGGAATCCGGCAAAGTGGCGCACTTCTGCTCTATGTGCGGGCCGAAATT
CTGTTCGATGAAAATCTCGCAAGAGGTGCGTGACTACGCGGCAACCCAGGCGATTGAAGTCGGTATGGTGGATAAATCCA
GCGACTTCCGCGCACGCGGCGGTGAGATCTACCTGAAGAGGGAGGAAGCCTGA

Protein sequence :
MSAKLTRREQRAQAQHFIDTLEGTAFPNSRRIYITGSQPDIRIPMREIQLSPTLTGGTKEHPQFEENEAVPVYDTSGPYG
DPDIAIDVQQGLAKLRAPWIAARDDSETLEQRSSVYTNERLADDGLDELRFSGLLTPRRAKPGQRVTQLHYARKGIVTPE
MEFIAIRENMGRERIRSEVLRKQHPGEGFGARLPENITPEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANIG
NSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLE
QAEQGVDYFTIHAGVLLRYVPMTAQRLTGIVSRGGSIMAKWCLSHHQENFLYTHFREICEICAAYDVSLSLGDGLRPGSI
QDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGIG
AAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFT
ARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQAIEVGMVDKSSDFRARGGEIYLKREEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 71
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69