Gene Information

Name : tpx (H650_02065)
Accession : YP_008106264.1
Strain : Enterobacter sp. R4-368
Genome accession: NC_021500
Putative virulence/resistance : Virulence
Product : lipid hydroperoxide peroxidase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 290109 - 290615 bp
Length : 507 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence : 
ATGTCACAACTCGTTCATTTTCAGGGCAATCCGGTTCCGGTTGCAGGCGCTATCCCGCAGGCTGGCGCAAAAGCCAGGCC
GTTCACGCTCGTGGCTAAAGACCTGTCCGACGTCGCACTGAGCCAGTTCGCGGGTAAACGTAAAGTGCTGAACATTTTCC
CAAGCATCGATACCGGCGTTTGCGCGGCTTCTGTGCGTAAATTTAACCAGTTAGCAACTGAGATGAACAACACCGTGGTG
CTGTGCATTTCTGCTGACCTGCCGTTTGCCCAGTCCCGTTTTTGCGGTGCTGAAGGTCTGAGCAATGTCATTACCCTTTC
GACGCTGCGCAGTGCTGACTTCCTCGAAAATTACGGTGTTGGCATCTCTGATGGCGCACTGAAAGGCCTTGCGGCGCGTG
CTGTGGTGGTGATTGACGAAAACGACACTGTTGTTTTCAGCCAGCTGGTGAATGAGATCACCAACGAGCCGGATTACACC
GCCGCGCTGGACGTGCTGAAAGGTTAA

Protein sequence : 
MSQLVHFQGNPVPVAGAIPQAGAKARPFTLVAKDLSDVALSQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEMNNTVV
LCISADLPFAQSRFCGAEGLSNVITLSTLRSADFLENYGVGISDGALKGLAARAVVVIDENDTVVFSQLVNEITNEPDYT
AALDVLKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-35 50
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 9e-36 50
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-35 50
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 6e-36 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_008106264.1 lipid hydroperoxide peroxidase VFG0087 Protein 3e-36 50