Gene Information

Name : guaA (H650_08325)
Accession : YP_008107495.1
Strain : Enterobacter sp. R4-368
Genome accession: NC_021500
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1609034 - 1610611 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; Derived by automated computational analysis using gene prediction method: GeneMarkS+.

DNA sequence :
ATGACGGACAACATTCATAAACATCGTATTCTTATCCTCGATTTTGGTTCTCAGTACACCCAACTGGTTGCGCGCCGCGT
GCGTGAACTGGGCGTTTACTGCGAACTGTGGGCGTGGGATGTCACCGAAGCGCAGATCCGCGACTTCAATCCAAGCGGCA
TCATCCTCTCCGGCGGCCCGGAAAGCACCACCGAAGACAACAGCCCGCGCGCACCGCAATATGTGTTCGAAGCTGGTGTG
CCGGTGCTTGGCGTCTGCTACGGCATGCAGACCATGGCGATGCAGCTCGGCGGCCACGTTGAAGGTTCTAACGAGCGTGA
ATTCGGCTACGCGCAGGTTGAAGTGCAGACCGACAGCGCGCTGGTTCGCGGTATTGAAGATTCGCTGACCGCAGAAGGCA
AAGTGCTGCTGGATGTGTGGATGAGCCACGGCGACAAAGTGACGGCGATCCCGTCTGACTTCGTCACCGTAGCCAGCACC
GAAAGCTGCCCGTTCGCCATCATGGCGAACGAAGAAAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTGACCCACAC
CCGCCAGGGGCTGCGTATGCTGGAGCGCTTTGTGCGCGACATCTGTGAATGTGAAGCGCTGTGGACGCCGGCAAAAATTA
TCGATGACGCCGTTGAGCGCATCCGTCAGCAGGTTGGCGATGACAAAGTGATCCTCGGCCTCTCCGGCGGCGTGGATTCT
TCAGTGACCGCGATGCTGCTGCACCGCGCTATCGGCAAAAATCTGACCTGCGTATTCGTTGATAACGGTCTGCTGCGTCT
GAACGAAGCTCAGCAGGTAATGGACATGTTTGGCGACCACTTCGGTCTGAACATTGTTCACGTTGAAGGGGAATCCCGTT
TCCTGGCCGCACTGGCCGGTGAGAACGATCCGGAAGCAAAACGTAAGATCATCGGCCGCGTGTTCGTGGAAGTGTTCGAC
GAAGAAGCACTGAAGCTGGAAGATGTGAAATGGCTGGCGCAGGGCACCATCTACCCGGACGTGATCGAATCCGCTGCTTC
GGCAACCGGTAAAGCGCACGTTATTAAATCTCACCACAACGTGGGCGGCCTGCCGAAAGAGATGAAGATGGGGCTGGTTG
AACCGCTGCGTGAGCTGTTCAAAGACGAAGTGCGTAAAATTGGTCTGGAACTGGGCCTGCCGTACGACATGCTGTACCGC
CATCCGTTCCCGGGGCCGGGCCTCGGTGTTCGCGTGCTGGGCGAAGTGAAGAAAGAGTATTGCGACCTGCTGCGCCGCGC
GGATGCGATCTTTATCGAAGAGCTGCATAAAGCCGATCTCTACAATAAAGTGAGCCAGGCTTTCACCGTGTTCCTGCCGG
TTCGCTCCGTGGGCGTGATGGGTGACGGTCGTAAATACGACTGGGTTGTCTCTCTGCGTGCAGTAGAAACCATCGACTTT
ATGACCGCACACTGGGCGCATCTGCCGTACGATTTCCTCGGCCGCGTCTCCAACCGCATCATCAACGAAGTGAACGGTAT
TTCGCGCGTGGTGTATGACATCAGCGGTAAACCGCCAGCTACGATTGAGTGGGAATAA

Protein sequence :
MTDNIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEDNSPRAPQYVFEAGV
PVLGVCYGMQTMAMQLGGHVEGSNEREFGYAQVEVQTDSALVRGIEDSLTAEGKVLLDVWMSHGDKVTAIPSDFVTVAST
ESCPFAIMANEEKRFYGVQFHPEVTHTRQGLRMLERFVRDICECEALWTPAKIIDDAVERIRQQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAQQVMDMFGDHFGLNIVHVEGESRFLAALAGENDPEAKRKIIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLRELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-128 52
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-128 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-128 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-110 48