Gene Information

Name : cadA2 (PCA10_45750)
Accession : YP_008104912.1
Strain : Pseudomonas resinovorans NBRC 106553
Genome accession: NC_021499
Putative virulence/resistance : Resistance
Product : cadmium-transporting P-type ATPase CadA2
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5050263 - 5052464 bp
Length : 2202 bp
Strand : +
Note : -

DNA sequence :
ATGAGCCACCATTGCTGCCACGACCATGACCACGCCCCCCGCTCCGCCACGCCGGACCTGGCGGCCATCGCTGCCAGCGC
CGAGCCGCGCTGGAGCAGCCTGCGCATCGACGCCATGGACTGCCCCACCGAGGAGCGCCTGATCCGCGATGCCCTGGGCA
AGGTCCCGGCCATCGAGGCGCTGGAATTCAACCTGATGCAGCGCCTGCTGCGGGTGCGCCACCGCTTCGACGACGCCGAG
CCCCTGCAGCGGCTGATCGAAAGCCTCGGCATGCAGGCGGTGCCGCTGGCCGAAGGCGCCGCCGCCACGGCCCCCGCCCA
GGCGCAGAAGCCCTGGTGGCCGCTGGCCCTGGCCGGTGTCGCCGCCCTGGCGGCGGAAGCCTGCGAATGGTTCGATCTCA
CGCCCGAGTGGGTGATCGCCGCCCTGGCCATACTGGCCATCCTCGGCGCCGGCCTGCCCACCTACAAGAAGGGCTGGATC
GCCCTGAAGAACCGCAACCTGAACATCAACGCGCTGATGAGCATCGCCGTGACCGGCGCCCTGCTGATCGGCCAGTGGCC
GGAAGCGGCCATGGTCAGCGTGCTGTTCGCCATCGCCGAACTGATCGAGGCCCGCTCCCTGGAGCGGGCGCGCGACGCCA
TTCGCGGCCTGCTGCAACTGGCCCCGGAGCAGGCCACGGTGTTCGAAGACGGCCAATGGCGCGAACGCCCCGCCCGCGAG
GTACAGCCCGGCGCGCGGCTGCGAGTGCGCCCCGGTGAGCGCATCGCCCTGGATGGCGAAGTCCTCGGCGGCCGTTCCAG
CGTCAACCAGGCGCCCATCACCGGAGAGAGCCTGCCGGTGGAGAAGGACCTGGGCGACCCGCTGTTCGCCGGCACCATCA
ATGGCGAGGGCGAACTGGAATACCGCGCCACCCGTGCCACCGACGACAGCACCCTGGCGCGCATCATCCACGCCGTGGAA
GCCGCCCAGGGCTCGCGGGCACCGACCCAGCGCTTCGTCGACCAGTTCTCGCGCATTTACACCCCGGTGGTGATTCTCAT
CGCGGTGTTCACCGCGCTGCTGCCGCCCCTGCTGCTGGGCGGCGCCTGGCTCGACTGGCTGTACCGCGCCCTGGTGCTGC
TGGTAATCGCCTGCCCCTGCGCCCTGGTGATTTCCACCCCCGTGACCATCGTCAGCGGCCTGGCCGCGGCGGCGCGAGGC
GGCATCCTGATCAAGGGCGGGGTGTTCCTCGAACTCGGCCGCAAGCTGGCCTGGATCGCCCTGGACAAGACCGGCACCCT
GACCGAAGGCCGCCCTCGGCAGACCGACCTGGAGTTGCTGCAACCGTCCGCAGGCAAAGCGCGCGCCCTGGCCGCCAGCC
TGGCGGCACGTTCCGACCACCCGGTGTCCCAGGCGGTGGCCCGCGCCGCGGAAGCCGACGGCATCGCCCTTTATGCCGTG
GACGGCCTGGCCGCCCTGCCCGGCCGGGGCGTCACCGGGTTGATCGAAGGCCGCGTCTATCACCTGGGCAATCACCGCCT
GATCGAGGAACTCGGCCTCTGCTCGGCGCAACTGGAAGCCCGCCTGGACGCCCTGGAGGCCCAGGGCAAGACGGTGGTGG
CGCTGTGCAGCGAACAGGCCGTGCTGGCCCTGTTCGCCGTGGCCGATACCCTGCGCGACAGCAGCCGCGAAGCCATAGCC
CAACTGCATGCCCTGGGGGTGAAGACGCTGATGCTCTCCGGCGACAACCAGCACACGGTGCAGGCCATCGCCAATCAGGT
GGGCGTGGATGACGCGCGCGGCAACCTGCTGCCCGAAGACAAGCTGGCGGAGATCGGCCTGCGCCAGGCCGGTGGCGTGC
CGGTGGGCATGGTCGGCGACGGCATCAACGACGCGCCGGCCCTGGCCCGCGCCGACATCGGCTTCGCCATGGGCGCCGCC
GGTACCGACACCGCTATCGAAACCGCCGGCGTGGCGCTGATGGACGACGACCTGCGCAAGCTGCCGCAGTTCATCCGCCT
GTCCCACCGCACCCATCGCGTGCTGATGCAGAACATCAGCCTGGCGCTGGGCATCAAGGCGGTCTTCCTGGTGCTGACGC
TGATGGGTGAAGGCACCCTGTGGATGGCGGTGTTCGCCGACATGGGCGCCAGCCTGCTGGTGGTGTTCAACGGGATGCGG
CTGCTTTCTCCCCTCTCCCTCCGGGAGAGGGGCCGGGGGTGA

Protein sequence :
MSHHCCHDHDHAPRSATPDLAAIAASAEPRWSSLRIDAMDCPTEERLIRDALGKVPAIEALEFNLMQRLLRVRHRFDDAE
PLQRLIESLGMQAVPLAEGAAATAPAQAQKPWWPLALAGVAALAAEACEWFDLTPEWVIAALAILAILGAGLPTYKKGWI
ALKNRNLNINALMSIAVTGALLIGQWPEAAMVSVLFAIAELIEARSLERARDAIRGLLQLAPEQATVFEDGQWRERPARE
VQPGARLRVRPGERIALDGEVLGGRSSVNQAPITGESLPVEKDLGDPLFAGTINGEGELEYRATRATDDSTLARIIHAVE
AAQGSRAPTQRFVDQFSRIYTPVVILIAVFTALLPPLLLGGAWLDWLYRALVLLVIACPCALVISTPVTIVSGLAAAARG
GILIKGGVFLELGRKLAWIALDKTGTLTEGRPRQTDLELLQPSAGKARALAASLAARSDHPVSQAVARAAEADGIALYAV
DGLAALPGRGVTGLIEGRVYHLGNHRLIEELGLCSAQLEARLDALEAQGKTVVALCSEQAVLALFAVADTLRDSSREAIA
QLHALGVKTLMLSGDNQHTVQAIANQVGVDDARGNLLPEDKLAEIGLRQAGGVPVGMVGDGINDAPALARADIGFAMGAA
GTDTAIETAGVALMDDDLRKLPQFIRLSHRTHRVLMQNISLALGIKAVFLVLTLMGEGTLWMAVFADMGASLLVVFNGMR
LLSPLSLRERGRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 9e-176 66
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-106 47
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-106 47
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-105 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA2 YP_008104912.1 cadmium-transporting P-type ATPase CadA2 BAC0298 Protein 2e-173 67
cadA2 YP_008104912.1 cadmium-transporting P-type ATPase CadA2 BAC0461 Protein 3e-78 43
cadA2 YP_008104912.1 cadmium-transporting P-type ATPase CadA2 BAC0092 Protein 3e-70 41
cadA2 YP_008104912.1 cadmium-transporting P-type ATPase CadA2 BAC0100 Protein 1e-53 41
cadA2 YP_008104912.1 cadmium-transporting P-type ATPase CadA2 BAC0124 Protein 6e-64 41