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Name : clpB (TPANIC_0071) Accession : YP_008090945.1 Strain : Treponema pallidum Nichols Genome accession: NC_021490 Putative virulence/resistance : Virulence Product : S14 family endopeptidase ClpB Function : - COG functional category : - COG ID : - EC number : 3.4.21.92 Position : 75914 - 78550 bp Length : 2637 bp Strand : - Note : - DNA sequence : ATGAACACAGACAGGTACACAGTCAAAGCAAGCGAAGCGCTCAATGACGCCATATCTCTGGCAGAAGCGGAGAACCACGG TCAAGTTGAGGAGGAACATCTACTCCACGCCCTACTTTCCCAGAAAGACGGGATTATCTCTCCGCTCATTGAAAAAATTG GGGCAAAACCGGACTTCCTGTACGATGAATTACTCCAATGCCTGCGCCGCAAACCACGTGTTACCGGTCCTGCCGCCCAA ACGCGCTGTGCACCAACGCTGAGCAAAGCCTGTGCACGTGCAGAACGCCTCGCGCTCAAGAACCAAGATGAATATGTCTC CTGCGAACATCTCCTGCTTGCCATAAGTGAGACAGATAGCAACACTGCACGTCTCCTTCACAGTCAGGGCATTACCAGTA AAACTATCAGTGCCGCCCTCAAAGATATACGCGGCAGCAAGCGCGTTACGAGCCAGGATCCAGAATCAACATTCCAGTGC TTGGAGAAATACTGCCGAGATCTTACTACCCTCGCCCGAGAAGAAAAAATAGATCCGGTTATTGGACGTGATGAAGAGAT CCGGCGCGTTATGCAGGTACTCTCACGTCGTACAAAAAATAACCCAGTGCTTATTGGAGAACCCGGCGTAGGGAAAACCG CTATTGTCGAGGGACTTGCACGCCGTATCGTTTCAGGAGACGTACCAGAAAGCCTCAAGGGAAAGCGTTTGCTTTCCCTT GACCTCGGCGCATTGGTTGCCGGTGCAAAGTTCCGCGGGGAATTTGAAGAACGACTAAAAGCGGTAATTGAAGCGGTACA GAAAAGCGACGGTGGCGTTATTTTATTCATTGATGAACTACACACGCTCGTAGGCGCCGGCGCAAGTGAGGGATCTATGG ATGCGTCGAACCTTCTGAAACCTGCGCTTGCGCGCGGTGAATTGCGTTCAATCGGCGCAACCACGCTCAACGAATATCGC AAATATATCGAAAAGGACGCAGCGCTCGAACGCCGCTTTCAGCAAGTGTACTGCGTACAGCCTACGGTGGAGGACACCAT TGCTATCCTGCGCGGTTTGCAAGAAAAGTACGAAGTGCATCACGGGGTACGTATCAAAGATGAAGCGCTTGTTGCAGCAA CCGTTTTGTCTGACCGTTACATCACCAACCGCTTTTTACCAGATAAGGCGATTGATCTGGTGGATGAAGCAGCAAGCCGC CTGAAAATGGAAATTGAAAGTCAGCCTGTTGAGCTAGACCAGGTGGAGCGCAAGATATTACAGCTGAATATCGAAAAGGC CTCTCTCCTTAAAGAAAGTGATCCGGCTTCAAAGGAACGTTTGGAAAAGTTAGAAAAAGAGCTCGCAGGCTTCCTAGAGC GCCGTGCTGCAATGCAGGTCCAATGGCAAAATGAGAAAGGGAGGATAGAAGAGTCACGCCGCTACAAAGAGGAGCTTGAG CGTCTCCGCATTGAGGAAACCATGTTTTCACGTGAAGGGGACCTGAACAAGGCTGCAGAACTTCGGTATGGCAAAATTCC AGAACTTGAAAAAAAAATCATGCTTCTTACTGCAGAAGTAGAGAAAAAATCCGGTCTAGAAGGACAGCTCTTGCGCGAGG AAGTGTGTGAAGAGGACATTGCGAAAATTATTTCTATGTGGACCGGAATTCCGGTATCCAAAATGATGGCAAGCGAGCAA CAGAAATATCTGCAGCTTGAGTCAGTACTCATGCAACGTGTGGTAGGGCAGGACGAAGCAGTGCGGGTAATTTCCGACGC GATTCGTCGTAATAAGGCAGGACTTTCTGATACGCGCCGTCCTCTTGGCAGTTTCTTATGTGTCGGTCCCACGGGGGTAG GAAAGACAGAACTTGCACGTACGTTAGCTGATTTTCTTTTCAACGATGAGCGTGCACTGACGCGTATCGATATGAGTGAA TACATGGAAAAACACGCGATCAGCCGACTCATTGGCGCGCCCCCGGGGTATGTGGGCTATGACGAGGGGGGACAATTGAC AGAAGCGGTACGACGTAGACCCTACAGCGTACTTCTTTTTGATGAAGTAGAGAAAGCGCACCAGGATGTGTTTAATATAT TCCTGCAAATACTCGACGATGGGCGCTTGACTGACGGCCAAGGAAGGGTGGTGGATTTCCGCAACACGATCATCATCATG ACCAGCAATATCGGATCAGAGCATATTCTTTCTGCACGCGAGTCGCGCACACACACGTCGGACTTGCCTGTACCCGAGAC ACAATCTACAGAAGAACAAACTCTACCAGAGCAGATACGGGGATTACTGCACACATACTTTCGCCCAGAATTCTTAAACC GGATTGACGAAGTGTTAATTTTTAAGCGTCTCACACGGAAACATATTCGCCTCATCACAGACATCCAACTGCAGATGGTA GTGGAGCGTTTGGAAAGTCGACATATAAAACTTCGTGTGCGTGACGCGGCGAAAGCCTATCTTGCGGAGCGCGGATACGA CGACACTTTCGGAGCACGACCACTGAAGCGTGCAATCCAAACGGAATTGGAAAATGCCCTAGCGCGTGAGATTCTCAGTG GCCGATTCAGAGGCGGCTCAACTATCGTGGTGGATATGTGTAAAGATGCTCTGTGTTTCACTGAACAAACATCCTGA Protein sequence : MNTDRYTVKASEALNDAISLAEAENHGQVEEEHLLHALLSQKDGIISPLIEKIGAKPDFLYDELLQCLRRKPRVTGPAAQ TRCAPTLSKACARAERLALKNQDEYVSCEHLLLAISETDSNTARLLHSQGITSKTISAALKDIRGSKRVTSQDPESTFQC LEKYCRDLTTLAREEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSGDVPESLKGKRLLSL DLGALVAGAKFRGEFEERLKAVIEAVQKSDGGVILFIDELHTLVGAGASEGSMDASNLLKPALARGELRSIGATTLNEYR KYIEKDAALERRFQQVYCVQPTVEDTIAILRGLQEKYEVHHGVRIKDEALVAATVLSDRYITNRFLPDKAIDLVDEAASR LKMEIESQPVELDQVERKILQLNIEKASLLKESDPASKERLEKLEKELAGFLERRAAMQVQWQNEKGRIEESRRYKEELE RLRIEETMFSREGDLNKAAELRYGKIPELEKKIMLLTAEVEKKSGLEGQLLREEVCEEDIAKIISMWTGIPVSKMMASEQ QKYLQLESVLMQRVVGQDEAVRVISDAIRRNKAGLSDTRRPLGSFLCVGPTGVGKTELARTLADFLFNDERALTRIDMSE YMEKHAISRLIGAPPGYVGYDEGGQLTEAVRRRPYSVLLFDEVEKAHQDVFNIFLQILDDGRLTDGQGRVVDFRNTIIIM TSNIGSEHILSARESRTHTSDLPVPETQSTEEQTLPEQIRGLLHTYFRPEFLNRIDEVLIFKRLTRKHIRLITDIQLQMV VERLESRHIKLRVRDAAKAYLAERGYDDTFGARPLKRAIQTELENALAREILSGRFRGGSTIVVDMCKDALCFTEQTS |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 4e-106 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_008090945.1 | S14 family endopeptidase ClpB | VFG2084 | Protein | 8e-103 | 43 |
| clpB | YP_008090945.1 | S14 family endopeptidase ClpB | VFG2076 | Protein | 7e-112 | 41 |
