Gene Information

Name : dhbE (BaLi_c39170)
Accession : YP_008079966.1
Strain : Bacillus licheniformis 9945A
Genome accession: NC_021362
Putative virulence/resistance : Virulence
Product : siderophore bacillibactin biosynthesis protein DhbE
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.7.58
Position : 3906275 - 3907897 bp
Length : 1623 bp
Strand : -
Note : 2,3-dihydroxybenzoate-AMP ligase

DNA sequence : 
ATGTTGAAAGGGTGCCCAACATGGCCGAAGGAGTTTGCGGATAAATATCGGAAGGAGGGATGCTGGCGAGGCGAAACATT
TGGGGGAATGCTGAGGGAACGGGCCGAAAAACATGGCAGCCGCATTGCCCTTACATACGGAGATACCCATTTAAGCTATC
AAGAGTTAGACAAGAGAGCCGACTCTTTGGCCGGCGGTCTTTTAAAGCTTGGGATCAAAAAAAATGACCGCGTCGTTGTC
CAGCTGCCGAATGTCATCGAGTTTTTTGAAGTTTGCTTTGCACTCTTCCGAATCGGAGCTCTGCCTGTCTTTGCGCTTCC
ATCGCACAGACATAGCGAGATCACGTATTTTTGCGAGTTTTCTGAAGCTGCTGCTTATGTGATTCCCGATCATCACGCAA
GGTTTGACTACCGCAAGCTGGCGAGACAGGTAAAGGGAAAGCTGCGGGGGCTTCGTCATGTCATTGTCGCCGGAGAATCG
GAGGAGTTTGAAGCGCTGTCGGGCCTTTATGATCAGCCTGCACCTCCGCAGAACGTCCATTCAGAAGATGTCGCTTTTCT
TCAGTTGTCAGGGGGAAGCACAGGTCTTTCTAAGCTGATCCCGAGGACGCATGATGATTATATATACAGCTTGAGGGTCA
GCGCAGAGATTTGCAGGCTTGATCACAACAGCGTGTATCTTGCCGCTCTTCCAATTGCTCACAATTATCCGCTTAGTTCG
CCGGGAGTGCTCGGTACACTCTATGCGGGAGGCCGAGTCGTTCTTGCGTCAGGAGGCAGCCCGGATGAAACCTTTCCTCT
GATCGAAAAGGAGAGGGTTACGATCACAGGTCTCGTACCGCCGCTTGCGCTAATCTGGCTTGACGCTGCTCCGGCGCGCC
GGGACGACTTGTCAAGTCTCCAGGTCCTTCAAGTCGGCGGAGCGAAATTCAGTGCCGAAGCCGCCAGACGCGTCACATCG
GTGTTTGGCTGCAAACTGCAGCAGGTTTATGGCATGGCAGAAGGTCTGGTCAACTATACCAGACTTGATGATCCTGAAGA
CACGATCGTTCACACACAAGGCAGACCGATGTCTCCGTTTGACGAAATTAAAATTGTGGATAAAGAAGGACGCGAACTTG
GACCCGGACAGACCGGGGAGCTTCTGACAAGAGGTCCTTATACGATCCGCGGCTATTACAAAGCTGAGGAACATAATGCC
AAAGCGTTCACAGAAGACGGGTTTTACCGTACGGGCGACTTGGTCAAAGTCAATTCATCAGGCTATTTGATTGTTGAAGG
ACGAGCCAAAGACCAGATCAACAGAGGCGGGGAGAAGGTTGCCGCGGAAGAAGTGGAAAACCACCTGCTCGCACATCCCG
CCGTACTCGATGCGGCGGTTGTCTCGATGCCGGATCAATTTCTCGGCGAAAGAACGTGTGCGTATGTTATTCCACGCGGC
GCTGCACCTGCTCAGGCTGAATTGCAATCGTTTTTGAGAGAAAGGGGCCTTGCAGCCTACAAAATACCCGACCGGGTGGA
AATGGTTGAAGCATTCCCGCAGACAGGCGTAGGAAAAGTCAGCAAAAAAGAACTGCGTACAGCGATTGCTGAAAAAATGT
CTGCAGCTAAGAATATCACGTGA

Protein sequence : 
MLKGCPTWPKEFADKYRKEGCWRGETFGGMLRERAEKHGSRIALTYGDTHLSYQELDKRADSLAGGLLKLGIKKNDRVVV
QLPNVIEFFEVCFALFRIGALPVFALPSHRHSEITYFCEFSEAAAYVIPDHHARFDYRKLARQVKGKLRGLRHVIVAGES
EEFEALSGLYDQPAPPQNVHSEDVAFLQLSGGSTGLSKLIPRTHDDYIYSLRVSAEICRLDHNSVYLAALPIAHNYPLSS
PGVLGTLYAGGRVVLASGGSPDETFPLIEKERVTITGLVPPLALIWLDAAPARRDDLSSLQVLQVGGAKFSAEAARRVTS
VFGCKLQQVYGMAEGLVNYTRLDDPEDTIVHTQGRPMSPFDEIKIVDKEGRELGPGQTGELLTRGPYTIRGYYKAEEHNA
KAFTEDGFYRTGDLVKVNSSGYLIVEGRAKDQINRGGEKVAAEEVENHLLAHPAVLDAAVVSMPDQFLGERTCAYVIPRG
AAPAQAELQSFLRERGLAAYKIPDRVEMVEAFPQTGVGKVSKKELRTAIAEKMSAAKNIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-116 49
ybtE CAA21394.1 - Virulence HPI Protein 2e-116 49
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 5e-116 49
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 1e-116 49
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 6e-116 49
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-116 49
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-116 49
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 2e-116 49
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-116 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhbE YP_008079966.1 siderophore bacillibactin biosynthesis protein DhbE VFG0168 Protein 2e-145 56
dhbE YP_008079966.1 siderophore bacillibactin biosynthesis protein DhbE VFG0932 Protein 6e-115 49
dhbE YP_008079966.1 siderophore bacillibactin biosynthesis protein DhbE VFG1817 Protein 9e-111 46