Gene Information

Name : cadA (LP6_2048)
Accession : YP_008063744.1
Strain : Legionella pneumophila Thunder Bay
Genome accession: NC_021350
Putative virulence/resistance : Resistance
Product : cadmium translocating P-type ATPase CadA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2313999 - 2316149 bp
Length : 2151 bp
Strand : -
Note : -

DNA sequence :
ATGCGGAAAAACCAAATGACAGTACCTTTAAATGAAACCAAATTTTTTGTTGCAGGACTTGATTGTCCAGCGGAAGAGCA
ACTAATCAGAAAGCAGTTACAGGATATTCCTGAAGTGGAGCAGTTGGATTTTAATTTTATTGCTGAAGAAGTTACTATTC
ATCACCGGTTGGCTTCAAGTGAAGAATTGCAAAAACGCATTGAGGCGTTGGGAATGAGTGTTCGAACGCTGGAAAGCACT
TTACCTATACCACAAAGAAAACAATTATCGTTGGATTTTTCCTGGAAAATTATTGGACTAGCAGGTTTTCTTGCCCTATT
TTCTGAGCTGGCAGCTTATTTTTTGGCTACGGAACAATCCATTTGGACTATTCTTCCAGCTTTGTTGGCTATTGGTCTTA
GTGGGCCTTCTACCTTTAAAAAAGGGTGGCTTGCCTTAGGGACTAAAACAATGAATATCAATAGCTTGATGTTCATTGCG
ATAGCAGGGGCTGTTCTTATTGGAGAGTGGCCTGAAGCGGCAATGGTGACTGTTTTATTTGCATTGGCCGAACGTATCGA
GCGCTACTCCTTAGATAAAGCACGTCTTGCGATTCGAAGCTTAATGCAAATTGCCCCTGAGGTGGCTTCAGTGAAACAGG
ACGATGGTCAATGGCAAACCTTGGCCATTGAAAAAGTGGTGCCTGGTGCTATTTTTAGAGTAAAACCTGGAGAGCGTATT
CCCCTGGATGGCGTGGTTATTTCAGGTCAGAGCACGGTCAATCAAGCGCCGATTACTGGTGAATCAATGCCAATAACAAA
AAAAGTGGGTGATTTGGTTTTTGCAGGAACATTAAATGAGCACGGCGCGTTTGAAGTGCAGGTCAGTAAAGTGTCAGGCG
ATACATTGCTTGCTAAAATTGGTAAAGCGATAGAGCAAGCGCAAGCGGATCGAGCTCCAACACAACGATTTGTTGATCAG
TTTTCTAAATATTATACTCCAATTATGGTATTGATGGCTTTTTTTGTTGCATTAATTCCACCTTTAGCATTTGGTTATCC
TTTTTATGATTCTCTTTATAAGTCACTGACTTTATTAGTTATTGCTTGCCCTTGCGCTTTAGTGATTTCAACACCCGTGA
CTGTTGTAAGTGGCCTTGCAGCGGCAGCAAAACAAGGGCTTCTTATTAAAGGAGGAAGCTACTTAGAGGTTGGTCATCGA
CTGAGGTTAATTGCTTTAGATAAGACAGGTACTTTAACGGAAGGAAAGCCAGTTGTAACTGACTTCATAGCTTGGGATGA
AAATCGAACTAAGGAGAGTTTGTTATTGTTAGCTGCAAGCCTTGATAGTCACTCAGAGCATCCAGTCGCTAATGCCTTAG
TACAGTACTGGCAACAGGAACAACCTCAAAACGCTTTACTTGAAATTGAGCAATTTTCAGCACTTCCTGGACGAGGAGTA
AAGGGATTAGTGGGTCAAGAACTCTATTTTGTAGGCAATCATCAGTTAGCTGAAGACAATCAGGTATGCAATCATTTTGT
CGAACAAGAGCTGAAGCGCTTGGAGGAAGAAGGTAAAACGACCGTAATATTAAGTAATGCTACGACTGTTTTGGCTATTT
TTGCAGTAGCTGATACTTTACGTGTTACAAGCCAACAGGCGATTGCACAACTACATGAACGGGGTATAAAAACCGCGATG
TTAACGGGAGACAATGCGGTAACGGCTCAGGCTATTGCTAAAAAAGTAGGTATTGATGAAGTAAATGCAAATATATTACC
TGCGGAAAAACTGCAAGCGATTAATGGTCTTTTAGATCACTATAATAGCGTTGGGATGGTAGGAGATGGAATTAATGATG
CCCCTGCATTGGCAAAAGCTACCGTGAGTTTTGCGATGGGGAAAGGAACAGATACTGCCTTAGAAACTGCAGACGTTGCC
CTAATGAACGACAATCTAGCAAGACTCCCCTTTTATATTGATTTAAGTCGTAAGACAGCACGTACTCTTTATCAAAACAT
CAGTTTATCTATTGCGATTAAAGGCATTTTCTTTATTTTGGCTCTTGTAGGGTATGCAACGTTATGGATGGCAGTTTTTG
CAGACATGGGAGCGAGTTTAATCGTAGTGGCTAATGGATTGCGATTGTTGTATATGTCCCCAGATGATTAA

Protein sequence :
MRKNQMTVPLNETKFFVAGLDCPAEEQLIRKQLQDIPEVEQLDFNFIAEEVTIHHRLASSEELQKRIEALGMSVRTLEST
LPIPQRKQLSLDFSWKIIGLAGFLALFSELAAYFLATEQSIWTILPALLAIGLSGPSTFKKGWLALGTKTMNINSLMFIA
IAGAVLIGEWPEAAMVTVLFALAERIERYSLDKARLAIRSLMQIAPEVASVKQDDGQWQTLAIEKVVPGAIFRVKPGERI
PLDGVVISGQSTVNQAPITGESMPITKKVGDLVFAGTLNEHGAFEVQVSKVSGDTLLAKIGKAIEQAQADRAPTQRFVDQ
FSKYYTPIMVLMAFFVALIPPLAFGYPFYDSLYKSLTLLVIACPCALVISTPVTVVSGLAAAAKQGLLIKGGSYLEVGHR
LRLIALDKTGTLTEGKPVVTDFIAWDENRTKESLLLLAASLDSHSEHPVANALVQYWQQEQPQNALLEIEQFSALPGRGV
KGLVGQELYFVGNHQLAEDNQVCNHFVEQELKRLEEEGKTTVILSNATTVLAIFAVADTLRVTSQQAIAQLHERGIKTAM
LTGDNAVTAQAIAKKVGIDEVNANILPAEKLQAINGLLDHYNSVGMVGDGINDAPALAKATVSFAMGKGTDTALETADVA
LMNDNLARLPFYIDLSRKTARTLYQNISLSIAIKGIFFILALVGYATLWMAVFADMGASLIVVANGLRLLYMSPDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 7e-159 52
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-123 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 6e-122 41
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 6e-122 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_008063744.1 cadmium translocating P-type ATPase CadA BAC0298 Protein 3e-157 52