Gene Information

Name : LP6_2045 (LP6_2045)
Accession : YP_008063741.1
Strain : Legionella pneumophila Thunder Bay
Genome accession: NC_021350
Putative virulence/resistance : Resistance
Product : Cd2+/Zn2+-exporting ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.5
Position : 2311087 - 2312994 bp
Length : 1908 bp
Strand : -
Note : -

DNA sequence :
ATGGGCTGCTCGACATGCTCTTCACATAAGGAGCCAATGCCAAAGTTGTGGCATAATCCCAAAGTCATTACAGCAACTAT
AGCTGGTTTATTATTAACTATTGGTTTTGTAGGCTCATATTTGGCATTACCAATGATTATCGCTAATGGGTTTTACATAG
GCGCAGTATTAATTGGCGGATATTATTTCGCACGCGAAGCAATAGACGAATTTATCAAAGAATATGAAATCGGTATTGAA
TTCTTGATGTCTCTTGCAGCCATTGTTGCAGGTATCATGGGGCAATGGGCGGAAGCAGCAACATTGGTATTTTTGTATTC
TATTTCTGAAGCTGCGGAAGGTTATTCCGGTGAAAGAGCGCGGCATGCTATCCGAGCATTGATGGATCTTGCCCCAAAAA
CAGCATTAATCCGGCGAAATAATACTGAATTTCGAATACCCATAGAAGAAATTCATATTGGAGATGAATTCATTGTTCTT
CCTGGTGAAAGTCTTGCTACAGATGGAGAAGTCATTTCAGGACATTCTAGTGTTAATCAAGCACCTATTACGGGTGAGTC
AATTCCAGTAGAAAAAACTATAGGGAGTAAAGTTTTTTCTGCAACTATAAACGGTGAAGGAACTCTTACTGTTCGTGCAA
CCAAAAAATTTGCTGATAATACATTATCTCGTATCATATTTCTTGTTGAAAAAGCACAAGACAAAAAGGGGCGTAGTCAA
CGTTTTATAGAACGTTTTGGCAACCTATATAGTCCATTTATCCTTTTGGCGGGAATACTCATAGCTACTTTACCACCTCT
ATTTGGGCAACCTTGGCAAGAGTGGGTGATTCGTGCCACAGTATTTATTGTTGCTGCAGCGCCATGTGCCCTAGTGATTT
CTATACCCATTACACTTGTAGCTGCTCTTGGCACAGCAAGTCGAAATGGAATATTACTAAAAGGTGGATTATATTTGGAG
CAACTAGTGAAGATAAAAGTTATTGCACTAGATAAAACAGGAACATTAACACAAGGTAAACCGAAGGTTACTGATATCAT
TCCATTGAATAACCATACTCGGAACCAAATTTTAAATGCAGCAGCAACTCTTGAATCGCGCTCCCAGCATCCCATGGCCC
AAGCCATTTTGCAACAAGCCAATGAAGAAAATATTCAATATAATCCTGTTGAACAGTTTAAGTCATTAACTGGTTCAGGT
GTACTTGGTTTTATCAATGGGAAAAAATTCTACATAGGCAATCCAAAATTATTTATTGATATGGGCCTATTGATAGAAAC
ATTAACGCAGGAAATAAATAAATTACAGGCCTCTGGAAAGACAGTAGTATTATTAGGAACTGATAAGGAAATCCTCGGTT
TAATTGCAATTGCTGATCCTCTAAGACCAACAGCAAGGCAGATGGTGTCTAACTTAAAATTGATGGGTATTGAACGTGTG
GTTATGCTCACAGGAGATAATTTGATAACTGCCTCTTCAATTGGTGAACAGGCGGGTGTTGATGAAGTATTTTCTGATTT
ATCACCAGAAGATAAGACACGAAAAATTGAAGAGTTAGAAAGACGTTATGGTAAGGTAATGATGGTTGGTGATGGAGTAA
ATGATGCTCCAGCACTCGCAGCAGCTCATGTAGGAGTTGCTATGGGTGCTGTCGGAACCGATGTTGCATTAGAAACTGCG
GATGTAGCCTTAATGGGTGATAATTTATTAAAATTACCTTATCTTATCGCATTTAGTCGTCGAACTTGGAATATAATTTT
ACAAAATTTGGGACTTTCTATAATTGTAATTAGCTCTCTTGTTGTCGGGGCAGTAACAGGTTATTTTACGTTGCCGATAG
CAGTTTTAGCTCATGAAATCAGTGAGCTTATTGTTATTGCAAGTGGTCTTCGTATGTTAAAATCTTAA

Protein sequence :
MGCSTCSSHKEPMPKLWHNPKVITATIAGLLLTIGFVGSYLALPMIIANGFYIGAVLIGGYYFAREAIDEFIKEYEIGIE
FLMSLAAIVAGIMGQWAEAATLVFLYSISEAAEGYSGERARHAIRALMDLAPKTALIRRNNTEFRIPIEEIHIGDEFIVL
PGESLATDGEVISGHSSVNQAPITGESIPVEKTIGSKVFSATINGEGTLTVRATKKFADNTLSRIIFLVEKAQDKKGRSQ
RFIERFGNLYSPFILLAGILIATLPPLFGQPWQEWVIRATVFIVAAAPCALVISIPITLVAALGTASRNGILLKGGLYLE
QLVKIKVIALDKTGTLTQGKPKVTDIIPLNNHTRNQILNAAATLESRSQHPMAQAILQQANEENIQYNPVEQFKSLTGSG
VLGFINGKKFYIGNPKLFIDMGLLIETLTQEINKLQASGKTVVLLGTDKEILGLIAIADPLRPTARQMVSNLKLMGIERV
VMLTGDNLITASSIGEQAGVDEVFSDLSPEDKTRKIEELERRYGKVMMVGDGVNDAPALAAAHVGVAMGAVGTDVALETA
DVALMGDNLLKLPYLIAFSRRTWNIILQNLGLSIIVISSLVVGAVTGYFTLPIAVLAHEISELIVIASGLRMLKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 1e-121 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 5e-120 45
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 5e-120 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
LP6_2045 YP_008063741.1 Cd2+/Zn2+-exporting ATPase BAC0298 Protein 9e-94 44
LP6_2045 YP_008063741.1 Cd2+/Zn2+-exporting ATPase BAC0092 Protein 1e-100 43
LP6_2045 YP_008063741.1 Cd2+/Zn2+-exporting ATPase BAC0100 Protein 1e-87 43
LP6_2045 YP_008063741.1 Cd2+/Zn2+-exporting ATPase BAC0124 Protein 1e-86 41